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Piribedil

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Identification
Molecular formula
C13H17NO
CAS number
3605-01-4
IUPAC name
4,4-diphenyl-1-pyrrolidin-1-yl-but-3-en-2-one
State
State
Piribedil is a solid at room temperature, typically handled in the form of tablets or powder.
Melting point (Celsius)
106.50
Melting point (Kelvin)
379.65
Boiling point (Celsius)
602.80
Boiling point (Kelvin)
875.95
General information
Molecular weight
298.41g/mol
Molar mass
298.4130g/mol
Density
1.0448g/cm3
Appearence

Piribedil typically appears as a white to off-white crystalline solid. It may have a slight odor and is generally supplied in powdered form or as tablets for medicinal use.

Comment on solubility

Solubility of 4,4-diphenyl-1-pyrrolidin-1-yl-but-3-en-2-one

The solubility of 4,4-diphenyl-1-pyrrolidin-1-yl-but-3-en-2-one in various solvents can be quite interesting, especially given its unique molecular structure. This compound, characterized by its dual phenyl rings and pyrrolidine moiety, exhibits specific solubility characteristics:

  • In Organic Solvents: Typically, this compound demonstrates good solubility in nonpolar and slightly polar organic solvents such as chloroform, ethanol, and acetic acid. The hydrophobic character of the phenyl groups contributes significantly to this behavior.
  • In Water: Conversely, solubility in water is very limited. This is primarily due to the hydrophobic nature of the compound, making it less favorable for interaction with polar solvent molecules.
  • Temperature Dependence: It is worth noting that solubility can be influenced by temperature. Increasing the temperature may enhance solubility in organic solvents, allowing for more effective dissolution.

“Like dissolves like” remains a guiding principle in understanding the solubility of this compound. The presence of rigid structures and large nonpolar segments like the phenyl rings leads to the following conclusions:

  • The compound is unlikely to form hydrogen bonds with water, which limits its overall aqueous solubility.
  • Its solubility profile supports its use in organic reactions and formulations, where nonpolar or moderately polar environments are prevalent.

In summary, while 4,4-diphenyl-1-pyrrolidin-1-yl-but-3-en-2-one is soluble in a variety of organic solvents, it exhibits poor solubility in water, adhering to fundamental chemical principles governing solubility.

Interesting facts

Interesting Facts about 4,4-Diphenyl-1-pyrrolidin-1-yl-but-3-en-2-one

4,4-Diphenyl-1-pyrrolidin-1-yl-but-3-en-2-one, commonly known in the scientific community as a compound of interest, exhibits fascinating properties and potential applications. Here are some noteworthy facts about this intriguing molecule:

  • Synthetic Utility: This compound acts as an important synthetic intermediate in various chemical reactions. Its unique structure allows it to participate in diverse reactions, leading to the creation of more complex organic molecules.
  • Pharmaceutical Applications: Many compounds with similar structures have been studied for potential pharmaceutical applications, including their roles as anti-inflammatory and analgesic agents. Researchers are investigating whether this compound could share similar benefits.
  • Research Significance: The structural features of 4,4-diphenyl-1-pyrrolidin-1-yl-but-3-en-2-one make it a valuable subject for studies in medicinal chemistry and material sciences. Its exploration can lead to innovations in drug discovery and development.
  • Mechanistic Insights: The compound’s distinct pyrrolidine ring can provide insights into the mechanisms of several reactions, aiding chemists in better understanding reaction pathways and kinetics.
  • Encouraging Research: Ongoing studies are looking at derivatives of this compound to enhance its efficacy and reduce potential side effects. Innovations in this area could pave the way for novel therapeutic agents.

In conclusion, 4,4-diphenyl-1-pyrrolidin-1-yl-but-3-en-2-one presents ample opportunities for research and application. As the scientific community continues to explore its potential, this compound reinforces the vast possibilities within the realm of chemistry.

Synonyms
BRN 1685264
3-BUTEN-2-ONE, 4,4-DIPHENYL-1-(1-PYRROLIDINYL)-
4,4-Diphenyl-1-(1-pyrrolidinyl)-3-buten-2-one
1976-54-1
DTXSID80173443
5-20-01-00286 (Beilstein Handbook Reference)
DTXCID8095934