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Ambroxan

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Identification
Molecular formula
C16H28O
CAS number
6790-58-5
IUPAC name
4,4,7a-trimethyl-6,7-dihydro-5H-benzofuran-2-one
State
State
Ambroxan is typically in a solid state at room temperature, appearing as crystalline flakes with a distinctive musky scent.
Melting point (Celsius)
27.00
Melting point (Kelvin)
300.15
Boiling point (Celsius)
289.00
Boiling point (Kelvin)
562.15
General information
Molecular weight
236.36g/mol
Molar mass
236.3570g/mol
Density
0.9792g/cm3
Appearence
Ambroxan appears as a white crystalline solid with a musky odor. It is a popular ingredient in perfumery due to its versatile scent profile that blends well with both floral and woodsy notes.
Comment on solubility

Solubility of 4,4,7a-trimethyl-6,7-dihydro-5H-benzofuran-2-one

The solubility of 4,4,7a-trimethyl-6,7-dihydro-5H-benzofuran-2-one, a complex organic compound, can be influenced by several factors. Generally, this compound exhibits moderate solubility characteristics in various solvents. Here are some key points regarding its solubility:

  • Polarity: The presence of functional groups within the molecule plays a significant role. If these groups are polar, the compound may demonstrate better solubility in polar solvents like water or alcohol.
  • Non-polar Solvents: Conversely, being a benzofuran derivative, it is likely to be more soluble in non-polar solvents such as hexane or chloroform, which can accommodate its hydrophobic regions.
  • Temperature: Increasing temperature often enhances solubility, allowing for increased interaction between solute and solvent molecules.
  • Concentration: A higher concentration of the compound in a solvent can lead to saturation, where no more solute can be dissolved, thus affecting the overall solubility dynamics.

In summary, understanding the solubility of 4,4,7a-trimethyl-6,7-dihydro-5H-benzofuran-2-one is crucial for its applications. Its solubility profile is not just a characteristic of the compound but a reflection of its molecular structure and the specific conditions in which it is dissolved. As the saying goes, "Like dissolves like." Therefore, selecting the right solvent that aligns with the compound's chemical properties will lead to optimal solubility.

Interesting facts

Interesting Facts about 4,4,7a-Trimethyl-6,7-dihydro-5H-benzofuran-2-one

This intriguing compound, known scientifically as 4,4,7a-trimethyl-6,7-dihydro-5H-benzofuran-2-one, reveals a fascinating interplay between structure and function in organic chemistry. Here are some engaging aspects of this compound:

  • Natural Occurrence: This compound is often found in various natural sources, especially within certain essential oils, where it contributes unique aromas and flavors.
  • Biological Significance: As a member of the benzofuran family, this compound can exhibit interesting biological activities, making it a subject of study in pharmacology for potential therapeutic applications.
  • Synthetic Routes: Chemists have developed several synthesis pathways to create this molecule, showcasing the versatility of organic synthesis in creating complex structures from simpler reagents.
  • Structural Insights: The distinct arrangement of the benzofuran ring system along with the trimethyl groups gives this compound unique stereochemical properties that can influence its reactivity and interactions with other chemical species.
  • Cultural Relevance: Compounds similar to this one are often discussed in the context of aromatherapy and natural products, where they are celebrated for their therapeutic potentials and sensory enhancement.

In summary, 4,4,7a-trimethyl-6,7-dihydro-5H-benzofuran-2-one provides a remarkable case study for understanding the connections between chemical structure, natural origin, and biological utility. Its complexity and significance make it a captivating topic for students and researchers alike.

Synonyms
5,6,7,7a-Tetrahydro-4,4,7a-trimethyl-2(4H)-benzofuranone
BH8469LVA9
FEMA NO. 4020
5,6,7,7a-Tetrahydro-4,4,7a-trimethylbenzofuran-2(4H)-one
Dihydroactinidiolide, (+-)-
(+-)-(2,6,6,-TRIMETHYL-2-HYDROXYCYCLOHEXYLIDENE)ACETIC ACID .GAMMA.-LACTONE [FHFI]
(+-)-(2,6,6,-TRIMETHYL-2-HYDROXYCYCLOHEXYLIDENE)ACETIC ACID GAMMA-LACTONE
15356-74-8
4,4,7a-Trimethyl-5,6,7,7a-tetrahydrobenzofuran-2(4H)-one
(+/-)-dihydroactinidiolide
(2,6,6-Trimethyl-2-hydroxycyclohexylidene)acetic acid lactone
2(4H)-Benzofuranone, 5,6,7,7a-tetrahydro-4,4,7a-trimethyl-
MFCD06409997
( inverted exclamation markA)-Dihydroactinidiolide
Dihydroactinolide
4,4,7a-Trimethyl-5,6,7,7a-tetrahydro-4H-Benzofuran-2-one
4,5,7,7a-Tetrahydro-4,4,7a-trimethyl-2(6H)benzofuranone
Dihydroactindiolide
UNII-BH8469LVA9
EINECS 239-390-4
4,4,7a-trimethyl-6,7-dihydro-5H-benzofuran-2-one
orb1304396
SCHEMBL3503557
CHEMBL2271411
DIHYDROACTINIDIOLIDE [MI]
DTXSID00864588
CHEBI:176780
2-Hydroxy-2,6,6-trimethylcyclohexylideneacetic acid gamma-lactone
BDBM50595063
NSC357087
AKOS015902000
CS-W022041
DIHYDROACTINIDIOLIDE, (+/-)-
FD33930
FS-3501
HY-W041301
DA-48596
DA-52539
FD158201
SY113388
NS00051943
4,4,7a-trimethyl-6,7-dihydro-5H-1-benzouran-2-one
Q27274663
2(4H)-Benzofuranone,6,7,7a-tetrahydro-4,4,7a-trimethyl-
2-Hydroxy-2,6,6-trimethylcyclohexylidene-1-acetic acid lactone
2(4H)-Benzofuranone,6,7,7a-tetrahydro-4,4,7a-trimethyl-, (R)-
2(4H)-Benzofuranone,6,7,7a-tetrahydro-4,4,7a-trimethyl-, (S)-
4,4,7a-Trimethyl-5,6,7,7a-tetrahydro-1-benzofuran-2(4H)-one #
(2,6,6-TRIMETHYL-2-HYDROXYCYCLOHEXYLIDENE)ACETIC ACID .GAMMA.-LACTONE
(+/-)-(2,6,6,-TRIMETHYL-2-HYDROXYCYCLOHEXYLIDENE)ACETIC ACID .GAMMA.-LACTONE [FHFI]
4 pound not4 pound not7a-Trimethyl-5 pound not6 pound not7 pound not7a-tetrahydrobenzofuran-2(4H)-one