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4,5-dibromo-1H-pyrazole

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Identification
Molecular formula
C3H2Br2N2
CAS number
4214-78-2
IUPAC name
4,5-dibromo-1H-pyrazole
State
State

At room temperature, 4,5-dibromo-1H-pyrazole is in a solid state.

Melting point (Celsius)
160.00
Melting point (Kelvin)
433.20
Boiling point (Celsius)
284.50
Boiling point (Kelvin)
557.70
General information
Molecular weight
240.87g/mol
Molar mass
240.8660g/mol
Density
2.4150g/cm3
Appearence

4,5-Dibromo-1H-pyrazole appears as a crystalline solid. Its color ranges from off-white to pale yellow. The compound is often prepared for purposes ranging from research in organic chemistry to its use in synthesis.

Comment on solubility

Solubility of 4,5-Dibromo-1H-pyrazole

4,5-Dibromo-1H-pyrazole, noted for its unique structure, presents distinct solubility characteristics that are important for its applications. Understanding its solubility helps in predicting its behavior in various environments:

  • Solvent Affinity: This compound generally exhibits solubility in organic solvents, such as ethanol and dimethyl sulfoxide (DMSO), but shows limited solubility in water.
  • Hydrophobic Nature: The presence of bromine substituents contributes to its hydrophobic properties, leading to lower interactions with polar solvents.
  • Concentration Dependency: The solubility is concentration-dependent, meaning that as more solvent is added, solubility may improve to a certain extent until saturation is reached.

It is important to note that the solubility characteristics can be influenced by factors like temperature and the presence of other ions or molecules in solution. Therefore, when working with 4,5-dibromo-1H-pyrazole, experimentation is key to determining the optimal conditions for dissolving this compound effectively.

Interesting facts

Interesting Facts about 4,5-Dibromo-1H-Pyrazole

4,5-Dibromo-1H-pyrazole is a fascinating chemical compound with numerous applications in the fields of chemistry and pharmaceuticals. Here are some intriguing points about this compound:

  • Structure and Stability: The unique 1H-pyrazole ring, incorporated with bromine atoms at the 4 and 5 positions, contributes to its chemical stability and reactivity. This makes it a valuable building block in organic synthesis.
  • Biological Activity: Compounds containing pyrazole moieties, like 4,5-dibromo-1H-pyrazole, are often investigated for their potential as *biologically active agents*. They have been found to exhibit a wide range of biological activities, including anti-inflammatory and antifungal properties.
  • Research Applications: In recent studies, 4,5-dibromo-1H-pyrazole has garnered attention for its potential use in developing new therapeutic drugs, particularly in the areas of cancer treatment and drug resistance.
  • Synthetic Versatility: Its functional groups provide opportunities for further chemical modifications, allowing chemists to tailor the compound for specific applications or to enhance its desired properties.
  • Environmental Impact: As with many halogenated compounds, understanding the environmental impact and degradation pathways of 4,5-dibromo-1H-pyrazole is essential for its safe application in industrial processes.

In conclusion, 4,5-dibromo-1H-pyrazole not only serves as a significant reagent in synthetic chemistry but also opens doors to exciting explorations in medicinal chemistry. As researchers continue to unveil its properties, this compound holds the promise of contributing to advancements in drug development and chemistry.

Synonyms
3,4-Dibromo-1H-pyrazole
660-928-2
5932-18-3
4,5-dibromo-1H-pyrazole
3,4-Dibromopyrazole
PYRAZOLE, 3,4-DIBROMO-
1H-Pyrazole, 3,4-dibromo-
NSC 222393
BRN 0002163
Pyrazole, 3,4(or 4,5)-dibromo-
MFCD00159639
NSC222393
Pyrazole,4-dibromo-
1H-Pyrazole,4-dibromo-
WLN: T5MNJ CE DE
4-23-00-00560 (Beilstein Handbook Reference)
3,4-Dibromo-1H-pyrazole #
pyrazole, 3(5),4-dibromo-
SCHEMBL7755979
SCHEMBL25256160
DTXSID70208056
DFUAIALZXKLUQU-UHFFFAOYSA-N
AKOS005266785
AKOS025394767
AT32872
NSC-222393
PS-11975
DB-314765
CS-0116767
EN300-1917825