4,5-dichloro-6-methyl-2-(methylsulfonyl)pyrimidine

Identification

Molecular formula

C₆H₅Cl₂N₂O₂S

CAS number

236849-69-7

IUPAC name

4,5-dichloro-6-methyl-2-methylsulfonyl-pyrimidine

State

At room temperature, this compound is in a solid state, presenting as a crystalline powder.

Melting point (Celsius)

166.00

Melting point (Kelvin)

439.15

Boiling point (Celsius)

345.00

Boiling point (Kelvin)

618.15

General information

Molecular weight

241.05g/mol

Molar mass

241.0540g/mol

Density

1.5200g/cm³

Appearence

4,5-dichloro-6-methyl-2-(methylsulfonyl)pyrimidine typically appears as a white to light yellow crystalline powder.

Comment on solubility

Solubility of 4,5-Dichloro-6-methyl-2-methylsulfonyl-pyrimidine

The solubility of 4,5-dichloro-6-methyl-2-methylsulfonyl-pyrimidine can be quite intriguing due to its specific structural characteristics. This compound, featuring both chloro and sulfonyl functional groups, exhibits various solubility behaviors depending on the solvent used. Here are some key points to consider:

Polar Solvents: Compounds containing sulfonyl groups often show good solubility in polar solvents such as water and alcohols. This is due to the ability of these solvents to facilitate hydrogen bonding and dipole interactions.
Non-Polar Solvents: Conversely, the presence of chloro groups may hinder solubility in non-polar solvents like hexane, as the overall hydrophobic character increases.
Temperature Effects: As with many compounds, solubility can increase with temperature; therefore, it may be beneficial to test solubility at varying temperatures.
pH Influence: The ionization state of the compound can also play a pivotal role in solubility—testing at different pH levels can provide insights into how this compound behaves in various environments.

In conclusion, the solubility characteristics of 4,5-dichloro-6-methyl-2-methylsulfonyl-pyrimidine are influenced by its functional groups, solvent properties, and environmental conditions. Understanding these factors will aid in predicting its behavior in practical applications. As always, experimental validation is recommended to assess solubility under specific conditions.

Interesting facts

Interesting Facts about 4,5-Dichloro-6-methyl-2-methylsulfonyl-pyrimidine

4,5-Dichloro-6-methyl-2-methylsulfonyl-pyrimidine is a fascinating compound in the realm of organic chemistry, primarily due to its unique structural features and versatile applications. Here are some notable aspects:

Structure and Reactivity: The compound belongs to the pyrimidine family, which is characterized by a six-membered aromatic ring containing two nitrogen atoms. The presence of chlorine and methylsulfonyl groups significantly influences its reactivity, making it an attractive target for synthetic transformations.
Role in Pharmaceuticals: This compound is known for its potential therapeutic applications. It serves as a precursor in the synthesis of various bioactive molecules, often utilized in drug discovery for its antimicrobial and anti-inflammatory properties.
Chlorine Atoms: The two chlorine atoms attached to the pyrimidine ring enhance the compound's ability to act as a halogenating agent, which is valuable in organic synthesis for creating more complex molecules.
Environmental Impact: Due to its chlorinated components, it is crucial to study the environmental effects of such compounds. Understanding their degradation pathways can help mitigate potential risks associated with their use and release.
Research and Development: Ongoing research on this compound focuses on its interactions with biological systems. Scientists are examining its mechanism of action, stability, and efficacy in various applications.

With its intriguing structural attributes and broad scope of applications, 4,5-dichloro-6-methyl-2-methylsulfonyl-pyrimidine continues to be a subject of interest in organic chemistry and medicinal research. As highlighted by researchers, "The exploration of such compounds paves the way for innovative solutions in drug development."

Synonyms

SCHEMBL7754111

4,5-dichloro-6-methyl-2-methylsulphonyl-pyrimidine