Skip to main content

4,5-dichloro-6-nitro-2-(trifluoromethyl)-1H-benzimidazole

ADVERTISEMENT
Identification
Molecular formula
C8H2Cl2F3N3O2
CAS number
374863-56-0
IUPAC name
4,5-dichloro-6-nitro-2-(trifluoromethyl)-1H-benzimidazole
State
State

Solid: At room temperature, this compound exists in a solid crystalline state.

Melting point (Celsius)
190.00
Melting point (Kelvin)
463.00
Boiling point (Celsius)
250.00
Boiling point (Kelvin)
523.00
General information
Molecular weight
319.97g/mol
Molar mass
319.9740g/mol
Density
1.8500g/cm3
Appearence

This compound generally appears as a yellow crystalline powder. Its color is attributable to the nitro group, which often imparts a distinct yellow hue to compounds.

Comment on solubility

Solubility of 4,5-dichloro-6-nitro-2-(trifluoromethyl)-1H-benzimidazole

The solubility of 4,5-dichloro-6-nitro-2-(trifluoromethyl)-1H-benzimidazole is an intriguing characteristic impacted by its unique chemical structure. This compound exhibits specific solubility behaviors influenced by several factors, which include:

  • Polarity: The presence of electron-withdrawing groups such as −Cl and −NO2, as well as the highly electronegative −CF3 group, can affect its overall polarity and interaction with various solvents.
  • Hydrogen bonding: The potential for hydrogen bonding with solvents may also play a significant role in determining solubility, particularly in polar solvents.
  • Solvent choice: Solubility can vary greatly depending on whether one uses polar or non-polar solvents. Generally, this compound may find better solubility in organic solvents compared to aqueous solutions.

As such, general observations regarding its solubility can be summarized as:

  1. It is likely more soluble in organic solvents like dichloromethane or ethanol.
  2. Its solubility in water is expected to be limited due to the bulky and non-polar character of the trifluoromethyl group.
  3. The presence of multiple halogens may introduce additional complexity to solubility assessments.

In summary, while 4,5-dichloro-6-nitro-2-(trifluoromethyl)-1H-benzimidazole presents challenges for solubility testing, understanding the factors at play allows for greater insight into its possible behavior in different environments. The interplay of these components highlights the fascinating nature of chemical solubility.

Interesting facts

Interesting Facts about 4,5-Dichloro-6-nitro-2-(trifluoromethyl)-1H-benzimidazole

The compound 4,5-dichloro-6-nitro-2-(trifluoromethyl)-1H-benzimidazole is a fascinating example of a complex organic molecule with noteworthy properties and applications. Here are some intriguing points to consider:

  • Pharmaceutical Applications: This compound belongs to a category of chemicals known for their potential medicinal properties. It is often explored for its role in developing pharmaceutical agents, particularly as potential antimicrobial or antifungal agents.
  • Structural Significance: The presence of both chlorinated and nitro functional groups in the molecular structure enhances its reactivity and versatility, making it a valuable building block in organic synthesis. The trifluoromethyl group is particularly significant in medicinal chemistry due to its ability to modulate biological activity.
  • Environmental Considerations: Compounds with halogen substituents, such as chlorines and trifluoromethyl groups, raise questions regarding their environmental impact and persistence. Scientists are increasingly interested in conducting studies to better understand the biodegradability and ecotoxicology of such substances.
  • Research Interest: The specificity of its structure has prompted studies into its electronic properties and interaction with biological targets, leading to deeper insights into its behavior in biological systems.
  • Potential in Material Science: Beyond medicinal applications, this compound and its derivatives are also investigated for their potential use in the development of new materials, such as advanced dyes and photonic devices.

As a chemistry student or enthusiast, exploring the intricacies of such compounds offers a window into the interplay of structure, reactivity, and application that defines the field of organic chemistry. The journey of understanding how functional groups affect a molecule's characteristics is both challenging and rewarding.

In the words of renowned chemist Linus Pauling, "The best way to have a good idea is to have a lot of ideas." This sentiment rings true as we delve into the myriad possibilities presented by compounds like 4,5-dichloro-6-nitro-2-(trifluoromethyl)-1H-benzimidazole.

Synonyms
BENZIMIDAZOLE, 4,5-DICHLORO-6-NITRO-2-(TRIFLUOROMETHYL)-
BRN 0930694
6609-42-3
4,5-Dichloro-6-nitro-2-(trifluoromethyl)benzimidazole
DTXSID60216286
DTXCID60138777
TZMZZAAWGRCWAY-UHFFFAOYSA-N