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4,5-dihydrobenzo[a]pyrene-4,5-diol

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Identification
Molecular formula
C20H14O2
CAS number
157140-26-2
IUPAC name
4,5-dihydrobenzo[a]pyrene-4,5-diol
State
State

At room temperature, the compound is in a solid state.

Melting point (Celsius)
300.00
Melting point (Kelvin)
573.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
252.28g/mol
Molar mass
252.2780g/mol
Density
1.3000g/cm3
Appearence

4,5-Dihydrobenzo[a]pyrene-4,5-diol is typically seen as a crystalline solid, often possessing a slight off-white to yellowish hue depending on purity and specific conditions of crystallization.

Comment on solubility

Solubility of 4,5-dihydrobenzo[a]pyrene-4,5-diol

The solubility of 4,5-dihydrobenzo[a]pyrene-4,5-diol in various solvents is influenced by its chemical structure and functional groups. This compound is known for its complex molecular arrangement, which plays a crucial role in how it interacts with different solvents.

In general, the solubility characteristics of this compound can be summarized as follows:

  • Polar solvents: This compound exhibits limited solubility in polar solvents like water due to its hydrophobic regions.
  • Non-polar solvents: Conversely, it shows enhanced solubility in non-polar organic solvents, such as hexane and benzene, where the hydrophobic interactions are more favorable.
  • Temperature dependence: Solubility can also vary with temperature; generally, an increase in temperature improves solubility in non-polar environments.

Due to its low water solubility and higher affinity for organic solvents, 4,5-dihydrobenzo[a]pyrene-4,5-diol demonstrates typical behavior observed in many polycyclic aromatic hydrocarbons (PAHs). Thus, researchers must consider solvent choice carefully when conducting experiments involving this compound.

Interesting facts

Interesting Facts about 4,5-Dihydrobenzo[a]pyrene-4,5-diol

4,5-Dihydrobenzo[a]pyrene-4,5-diol is a fascinating chemical compound with significant relevance in environmental science and health research. Here are some remarkable insights into this compound:

  • Polycyclic Aromatic Hydrocarbon (PAH): This compound belongs to a class of chemicals known as polycyclic aromatic hydrocarbons, which are composed of multiple fused aromatic rings. PAHs are widely recognized for their potential mutagenic and carcinogenic properties.
  • Formation: 4,5-Dihydrobenzo[a]pyrene-4,5-diol is typically generated through the metabolic activation of benzo[a]pyrene, a well-known environmental pollutant found in substances like tobacco smoke and grilled or charred foods.
  • Health Implications: Due to its structure, this compound has drawn attention in cancer research. Studies suggest that it may participate in DNA adduct formation, a critical process in the development of malignancies.
  • Environmental Concerns: As a derivative of one of the most studied PAHs, its persistence in the environment raises concerns. Understanding its degradation pathways can be crucial for developing strategies to mitigate its effects in ecosystems.
  • Analytical Techniques: Researchers often use sophisticated analytical methods such as high-performance liquid chromatography (HPLC) and mass spectrometry to detect and quantify this compound in biological and environmental samples.

In summary, 4,5-dihydrobenzo[a]pyrene-4,5-diol stands as an essential compound within the larger context of PAHs, drawing interest from various scientific disciplines due to its implications for human health and environmental health. Its study not only augments our understanding of cancer mechanisms but also highlights the importance of monitoring and regulating environmental pollutants.

Synonyms
4,5-Dihydro-4,5-dihydroxybenzo(a)pyrene
28622-84-6
4,5-Dihydroxy-4,5-dihydrobenzo(a)pyrene
benzo(a)pyrene-4,5-dihydrodiol
B(a)P-4,5-diol
RefChem:96506
BP-4,5-Dihydrodiol
4,5-dihydrobenzo[a]pyrene-4,5-diol
Benzo(a)pyrene, 4,5-dihydroxy-4,5-dihydro-
BENZO(a)PYRENE, 4,5-DIHYDRO-4,5-DIHYDROXY-
DTXSID40951289
37571-88-3
SCHEMBL3344522
4,5-Dihydro-4,5-dihydroxybenzpyrene
4,5-Dihydrobenzo[pqr]tetraphene-4,5-diol
4,5-Dihydrobenzo[def]chrysene-4,5-diol #