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4,5-Dihydrothiazol-2-amine

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Identification
Molecular formula
C3H6N2S
CAS number
4967-26-0
IUPAC name
4,5-dihydrothiazol-2-amine
State
State

At room temperature, 4,5-dihydrothiazol-2-amine is typically a solid.

Melting point (Celsius)
92.00
Melting point (Kelvin)
365.15
Boiling point (Celsius)
229.00
Boiling point (Kelvin)
502.15
General information
Molecular weight
102.15g/mol
Molar mass
102.1540g/mol
Density
1.1740g/cm3
Appearence

4,5-Dihydrothiazol-2-amine typically appears as a white to off-white crystalline powder. It is characterized by its stable crystalline structure and can exhibit some level of hygroscopicity, depending on the ambient conditions.

Comment on solubility

Solubility of 4,5-dihydrothiazol-2-amine

4,5-dihydrothiazol-2-amine, possessing the chemical formula C4H6N2S, has intriguing solubility characteristics that can be examined in various solvents.

General Observations:

This compound is known for being:

  • Moderately soluble in water: 4,5-dihydrothiazol-2-amine demonstrates a reasonable degree of solubility, which can be influenced by pH levels.
  • Soluble in polar organic solvents: Often dissolving effectively in solvents like ethanol and methanol.
  • Insoluble in nonpolar solvents: This indicates its hydrophilic nature, as compounds with amine and thiazole groups typically prefer polar environments.

Factors Affecting Solubility:

The solubility of 4,5-dihydrothiazol-2-amine is influenced by several key factors:

  • Temperature: Increased temperatures usually enhance the solubility of solid solutes in liquids.
  • pH: Depending on the acidity or alkalinity of the solution, the protonation state of the amine group can affect solubility.
  • Presence of other ions or molecules: When combined with salts or other solutes, solubility dynamics can change significantly.

Understanding the solubility profile of 4,5-dihydrothiazol-2-amine is crucial for its applications in biological and chemical processes. In summary, the interplay of its unique chemical structure and the surrounding environment dictates its overall solubility, making it a compound of interest in various scientific endeavors.

Interesting facts

Interesting Facts about 4,5-Dihydrothiazol-2-amine

4,5-Dihydrothiazol-2-amine is a fascinating compound that plays a significant role in various chemical and biological applications. Here are some interesting insights into this unique molecule:

  • Structural Features: This compound features a thiazole ring, which is notable for its five-membered heterocyclic structure containing both sulfur and nitrogen. The dihydro configuration highlights the presence of reduced double bonds, which can influence its reactivity.
  • Biological Significance: Compounds containing thiazole rings have been shown to exhibit a wide range of biological activities, including antimicrobial, antifungal, and antiviral properties. The incorporation of an amine group further amplifies its potential interactions in biological systems.
  • Synthetic Versatility: 4,5-Dihydrothiazol-2-amine can be synthesized through various pathways, making it a valuable intermediate in organic synthesis. **Chemists often explore novel synthetic methods to improve yields and reduce environmental impact.**
  • Applications: Due to its structural attributes, this compound is a candidate for the development of pharmaceuticals and agrochemicals. Researchers are particularly interested in its potential as a building block for more complex molecules.
  • Research Exploration: As scientists delve deeper into the chemistry of thiazoles, they continue to uncover new derivatives and modifications that can lead to enhanced functionalities or novel applications. The ongoing study of such compounds exemplifies the dynamic nature of chemical research.

In conclusion, 4,5-dihydrothiazol-2-amine serves as a prime example of how simple compounds can exhibit complex behaviors and hold significant importance in both the scientific community and industry. Its intriguing structure and potential applications make it a worthwhile subject of study for chemists and researchers alike.

Synonyms
2-Amino-2-thiazoline
2-Aminothiazoline
1779-81-3
2-Thiazolamine, 4,5-dihydro-
4,5-Dihydro-1,3-thiazol-2-amine
2-Thiazolidinimine
2-Iminothiazolidine
2-Amino-4,5-dihydrothiazole
2-Thiazoline, 2-amino-
2-Amino-4,5-dihydrothiazoline
USAF PD-57
2-Thiazolin-2-ylamine
4,5-DIHYDRO-2-THIAZOLAMINE
2-Aminothiazoline (VAN)
NSC 3110
NSC 24626
EINECS 217-224-1
2-amino-4,5-dihydro-1,3-thiazole
5JC2YZG56Q
CAMFAZOLINUM
CHEBI:40889
NSC-3110
NSC-24626
2-amino-Delta(2)-thiazoline
DTXSID4061961
Revercan
DTXCID1035658
4,5-dihydrothiazol-2-amine
MFCD00005313
Thiazolidin-(2E)-ylideneamine
2-Amino-.DELTA.2-thiazoline
CHEMBL362148
NSC3110
NSC24626
2-Thiazolamine,5-dihydro-
WLN: T5N CS AUTJ BZ
UNII-5JC2YZG56Q
iminothiazolidine
2-amino-thiazoline
thiazolidin-2-imine
1,3-Thiazolidin-2-imine
SCHEMBL354824
2-Amino-2-thiazoline, 97%
4,5-dihydro-thiazol-2-ylamine
2-Amino-4, 5-dihydrothiazoline
4,5-dihydro-thiazol-2-yl-amine
ALBB-030173
STR00410
BBL000029
BDBM50150920
STK282915
2-imino-2,3,4,5-tetrahydrothiazole
AKOS003268141
AKOS003269613
AC-8411
DB02335
4,5-Dihydro-1,3-thiazol-2-amine #
PD008035
SY017228
DB-044318
CS-0074129
NS00071582
EN300-33927
H11788
A812329
Q27093350
F0001-0648
Z1954804762
InChI=1/C3H6N2S/c4-3-5-1-2-6-3/h1-2H2,(H2,4,5