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Allantoin

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Identification
Molecular formula
C4H6N4O3
CAS number
97-59-6
IUPAC name
4,5-dihydroxy-1,3-bis(hydroxymethyl)imidazolidin-2-one
State
State

At room temperature, allantoin is a solid.

Melting point (Celsius)
230.00
Melting point (Kelvin)
503.15
Boiling point (Celsius)
355.00
Boiling point (Kelvin)
628.15
General information
Molecular weight
158.12g/mol
Molar mass
158.1210g/mol
Density
1.4503g/cm3
Appearence

Allantoin appears as a white odorless crystalline powder. It is often used in pharmaceutical and cosmetic preparations.

Comment on solubility

Solubility Characteristics of 4,5-dihydroxy-1,3-bis(hydroxymethyl)imidazolidin-2-one

The solubility of 4,5-dihydroxy-1,3-bis(hydroxymethyl)imidazolidin-2-one is influenced by several factors, primarily its functional groups and polarity. This compound contains multiple hydroxyl (-OH) groups, which typically enhance solubility in polar solvents.

Key points regarding its solubility include:

  • Polar solvents: Due to its extensive hydrogen bonding capabilities, 4,5-dihydroxy-1,3-bis(hydroxymethyl)imidazolidin-2-one is expected to be highly soluble in water, making it suitable for aqueous applications.
  • Non-polar solvents: Conversely, solubility in non-polar solvents is likely to be very low, as the hydrophilic character dominates.
  • Temperature dependency: Like many compounds, its solubility may increase with temperature, allowing for greater interaction with the solvent.
  • Mixtures: In possible mixtures, the presence of other solutes could further modify its solubility behavior.

In conclusion, the solubility of 4,5-dihydroxy-1,3-bis(hydroxymethyl)imidazolidin-2-one can be broadly characterized as high in polar environments and limited in non-polar settings, making it a versatile compound in various chemical processes.

Interesting facts

Interesting Facts about 4,5-Dihydroxy-1,3-bis(hydroxymethyl)imidazolidin-2-one

4,5-Dihydroxy-1,3-bis(hydroxymethyl)imidazolidin-2-one, often referred to in scientific literature as a multifunctional compound, is quite fascinating for several reasons:

  • Biochemical Relevance: This compound plays a significant role in various biochemical processes, particularly in the field of nutrition and metabolism. Its hydroxyl groups enhance its reactivity, making it a good candidate in synthesizing more complex molecules.
  • Applications in Medicine: 4,5-Dihydroxy-1,3-bis(hydroxymethyl)imidazolidin-2-one is of interest in drug formulation. Research indicates that it can potentially be utilized in developing therapeutic agents due to its structural characteristics.
  • Polyol Characteristics: Its structure includes multiple hydroxymethyl groups, which exhibit polyol properties, making this compound a valuable resource for creating hydrophilic polymers.
  • Stability and Reactivity: The diol and amine functionalities present in the structure contribute to its unique stability profile while allowing for various reaction pathways. This reactivity is particularly noteworthy in organic synthesis.
  • Investigational Uses: Scientists are exploring the possibilities of using this compound in glycosylation reactions, which are critical in manufacturing glycoproteins and glycoconjugates essential for cellular communication.

As you can see, 4,5-dihydroxy-1,3-bis(hydroxymethyl)imidazolidin-2-one is a compound with a promising future in both research and practical applications. Its versatility in organic synthesis and potential utility in medicinal chemistry makes it an exciting subject of study in the field of modern chemistry.

Synonyms
4,5-Dihydroxy-1,3-bis(hydroxymethyl)imidazolidin-2-one
DIMETHYLOLDIHYDROXYETHYLENEUREA
N,N'-Dimethylolglyoxal monoureine
Dimethylol dihydroxyethyleneurea
CCRIS 4804
HSDB 4358
NCI-C60322
OKU7IX3H6E
N,N'-Dimethylol-4,5-dihydroxyethyleneurea
EINECS 217-451-6
2-Imidazolidinone, 4,5-dihydroxy-1,3-bis(hydroxymethyl)-
BRN 0881343
4,5-Dihydroxy-1,3-bis(hydroxymethyl)-2-imidazolidinone
UNII-OKU7IX3H6E
2-Imidazolidinone, 1,3-bis(hydroxymethyl)-4,5-dihydroxy-
DTXSID1025140
DIMETHYLOLGLYOXALMONOUREINE
5-25-02-00369 (Beilstein Handbook Reference)
n,n'-dimethyloldihydroxyethyleneurea
DIHYDROXYDIMETHYLOLETHYLENEUREA
DIHYDROXYETHYLENEDIMETHYLOLUREA
DIMETHYLOLDIHYDROXYIMIDAZOLIDINONE
1,3-dimethylol-4,5-dihydroxyimidazolidone
BIS(HYDROXYMETHYL)DIHYDROXYETHYLENEUREA
DIMETHYLOL DIHYDROXYETHYLENEUREA [HSDB]
4,5-dihydroxy-1,3-dimethylol-2-imidazolidinone
1,3-DIMETHYLOL-4,5-DIHYDROXYETHYLENEUREA
4,5-DIHYDROXY-1,3-DIMETHYLOLETHYLENEUREA
4,5-DIHYDROXY-N,N'-DIMETHYLOLETHYLENEUREA
N,N'-Bis(hydroxymethyl)-4,5-dihydroxyethyleneurea
1,3-bis(hydroxymethyl)-4,5-dihydroxy-2-imidazolidinone
1,3-DIMETHYLOL-4,5-DIHYDROXY-2-IMIDAZOLIDINONE
4,5-DIHYDROXY-2-OXO-1,3-DIMETHYLOLIMIDAZOLIDINE
N,N'-DIMETHYLOL-4,5-DIHYDROXY-2-IMIDAZOLIDINONE
1,3-BIS(HYDROXYMETHYL)-4,5-DIHYDROXYIMIDAZOLIDONE
1,3-BIS(HYDROXYMETHYL)-4,5-DIHYDROXY-2-IMIDAZOLIDONE
1,3-DI(HYDROXYMETHYL)-4,5-DIHYDROXY-2-IMIDAZOLIDINONE
AHURAMINE YX
CARBAMOL GL
FINISH KVSI
FIXAPRET CPA
KARBAMOL GL
NEUPERM GFK
FINISH KVS
REACT HE
NEUPERM 6FN
PERMAFURESSHU LKS
SARCOSET 6M
PERMAFRESH LF 2
KNITTEX EVERFIT LE
PERMAFRESH 182
SUMITEX NS 19
AEROTEX 900
DIMETHYLOLGLYGOXALUREA
REACTANT 2035
VALREZ 248
FIXAPRET TX 2386
SUMITEX RESIN NS 19
INTEX 510
DIMETHYLOGLYOXAMONOUREINE
DTXCID905140
N,N'Dimethylolglyoxal monoureine
N,N'Dimethylol4,5dihydroxyethyleneurea
4,5Dihydroxy1,3bis(hydroxymethyl)2imidazolidinone
2Imidazolidinone, 4,5dihydroxy1,3bis(hydroxymethyl)
1,3-bis(hydroxymethyl)-4,5-dihydroxy-2-imidazolinone
(4,5-DIHYDROXY-1,3-BIS(HYDROXYMETHYL)-2-IMIDAZOLIDINONE
1854-26-8
Arkofix
Sumitex NS
Dimethylolglyoxalurea
Dimethyloldihydroxyethylene urea
Dmdheu
Depremol G
Permafresh LF
Permafresh LH
Permafresh LKS
Protocol C
Verapret DKh
Cassurit LR
Firmatex RK
Fixapret CP
Sarcoset GM
Verapret DH
Arkofix NG
Fixapret CPK
Fixapret CPN
Knittex LE
Readpret KPN
Fixapret CPNS
Neuperm GFN
Reapret KPN
Sumitex FSK
Hylite LF
Permafresh 113B
Permafresh 183
Sumitex NS 2
Sumitex NS 1SPE
Fixapret CP 40
Sumitex NS 1 SPE
PROX DW
1,3-DIHYDROXYMETHYL-4,5-DIHYDROXYIMIDAZOL-2-ONE
2-Imidazolidinone, 4,5-dihydroxy-1,3-bis
SCHEMBL213947
ZEYUSQVGRCPBPG-UHFFFAOYSA-N
EINECS 270-150-1
AKOS006275420
NS00019553