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Genistein

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Identification
Molecular formula
C15H10O5
CAS number
446-72-0
IUPAC name
4,5-dihydroxy-3-(4-hydroxyphenyl)-6-methoxy-chromen-7-one
State
State

Genistein is typically a solid at room temperature, appearing as a crystalline material. It maintains this solid state under standard conditions.

Melting point (Celsius)
297.00
Melting point (Kelvin)
570.20
Boiling point (Celsius)
715.10
Boiling point (Kelvin)
988.30
General information
Molecular weight
270.24g/mol
Molar mass
270.2410g/mol
Density
1.5270g/cm3
Appearence

Genistein is a yellow crystalline powder that is soluble in DMSO and ethanol but poorly soluble in water. When in pure form, it typically appears as a bright yellow to yellow-orange crystalline solid.

Comment on solubility

Solubility of 4,5-dihydroxy-3-(4-hydroxyphenyl)-6-methoxy-chromen-7-one

The solubility of 4,5-dihydroxy-3-(4-hydroxyphenyl)-6-methoxy-chromen-7-one is influenced by several factors, primarily due to its complex structure. Here are some key points regarding its solubility:

  • Polarity: The presence of hydroxyl groups (-OH) contributes to increased polarity, which generally enhances solubility in polar solvents such as water.
  • Solvent Interactions: This compound may exhibit variable solubility in organic solvents. Common solvents include:
    • Dimethyl sulfoxide (DMSO)
    • Methanol
    • Ethyl acetate
  • Temperature Effects: Like many organic compounds, its solubility can increase with temperature; therefore, heating the solvent may improve dissolution.
  • pH Sensitivity: The ionization state of the hydroxyl groups may change with pH, potentially affecting solubility in aqueous environments.

In summary, while 4,5-dihydroxy-3-(4-hydroxyphenyl)-6-methoxy-chromen-7-one shows promising solubility characteristics, it is essential to consider the specific conditions of the dissolution process. As noted, factors like polarity, solvent choice, temperature, and pH play critical roles in determining the solubility of this compound.

Interesting facts

Interesting Facts about 4,5-dihydroxy-3-(4-hydroxyphenyl)-6-methoxy-chromen-7-one

This intriguing compound belongs to the flavonoid family and is often recognized for its remarkable biological activities. Flavonoids, known for their *phenolic structures*, play a pivotal role in plant physiology and human health.

Key Features

  • Antioxidant Properties: This compound exhibits strong antioxidant capabilities, helping to combat oxidative stress in living organisms.
  • Anti-inflammatory Effects: Studies have suggested that it may possess anti-inflammatory properties, making it a subject of interest in research regarding chronic inflammation.
  • Neuroprotective Potential: Preliminary studies indicate potential neuroprotective effects, hinting at its role in defending against neurodegenerative diseases.
  • Traditional Uses: Like many flavonoids, it has been traditionally utilized in herbal remedies, emphasizing its long-standing significance in folk medicine.

The *molecular structure* of this compound features several hydroxyl groups, which serve as key sites for biochemical interactions. Researchers are continually exploring the implications of these interactions in terms of developing new therapeutic strategies.

Research and Applications

Ongoing investigation into 4,5-dihydroxy-3-(4-hydroxyphenyl)-6-methoxy-chromen-7-one not only enhances our understanding of flavonoids but also illuminates potential applications in medicine and *nutraceuticals*. As noted by some researchers, *"The rich complexity of flavonoids like this compound opens doors to innovative treatment options in modern pharmacology."*

Through this exploration, scientists aim to harness the natural benefits locked within such compounds, paving the way for breakthroughs in health and wellness.