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Isorhamnetin

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Identification
Molecular formula
C16H12O6
CAS number
480-19-3
IUPAC name
4,5-dihydroxy-8-methoxy-2-phenyl-chromen-7-one
State
State
Isorhamnetin is typically found as a solid at room temperature. It is stable under normal conditions and can be found in its crystalline or powdery form. The material is generally stable unless exposed to strong acids or bases.
Melting point (Celsius)
299.00
Melting point (Kelvin)
572.00
Boiling point (Celsius)
310.00
Boiling point (Kelvin)
583.00
General information
Molecular weight
316.27g/mol
Molar mass
316.2670g/mol
Density
1.6710g/cm3
Appearence
Isorhamnetin is a yellow crystalline powder. Its vibrant yellow color is typical of many flavonoids, which can also display different hues depending on their specific structure and degree of hydroxylation or methoxylation. The compound is generally odorless and may crystallize in needle-like formations or in a powdery form.
Comment on solubility

Solubility of 4,5-dihydroxy-8-methoxy-2-phenyl-chromen-7-one

The solubility of 4,5-dihydroxy-8-methoxy-2-phenyl-chromen-7-one is influenced by several factors, primarily due to its functional groups and the presence of a chromone structure. Here are some key points about its solubility:

  • Polar vs. Nonpolar solvents: This compound may exhibit better solubility in polar solvents such as ethanol and methanol, due to the presence of hydroxyl groups (-OH) that can form hydrogen bonds.
  • Influence of the methoxy group: The methoxy (-OCH3) group enhances the overall polarity of the molecule, potentially improving its solubility in polar solvents.
  • Stable aromatic structure: Being a phenyl-substituted chromone, its aromatic regions can influence solubility, making it less soluble in nonpolar solvents like hexane or chloroform.
  • pH effects: The solubility can also be affected by pH; under acidic or basic conditions, the ionization of the hydroxyl groups could further alter its solubility profile.

In summary, while the solubility of 4,5-dihydroxy-8-methoxy-2-phenyl-chromen-7-one is favorable in polar solvents due to its functional groups, its behavior can vary significantly based on the solvent used and environmental conditions. Proper selection of solvents is crucial for applications involving this compound.

Interesting facts

Interesting Facts about 4,5-Dihydroxy-8-methoxy-2-phenyl-chromen-7-one

This compound, commonly referred to in scientific literature due to its unique structural characteristics, is a *flavonoid*, which is a class of compounds known for their diverse biological activities. Here are some fascinating aspects:

  • Natural Sources: This compound belongs to a group that is derived from plants. Flavonoids are widely distributed in the plant kingdom, particularly in fruits, vegetables, and herbs, hinting at their potential health benefits.
  • Biological Activities: Research has suggested that flavonoids, including this compound, may exhibit a variety of activities such as:
    • Antioxidant properties, helping to combat oxidative stress.
    • Anti-inflammatory effects, potentially useful in reducing inflammation.
    • Antimicrobial action, making this compound a candidate for investigating its effects against various pathogens.
  • Structural Features: The presence of hydroxyl groups in its structure is noteworthy because they often contribute to the compound's reactivity and interaction with biological systems. The methoxy group further influences its solubility and biological activity.
  • Research Interest: Scientists are increasingly interested in this particular flavonoid for its possible role in pharmacology. It is thought to have potential therapeutic applications in treating various diseases, including certain cancers and neurodegenerative disorders.
  • Synthesis: The synthetic pathways of such compounds often involve intricate chemical reactions, showcasing the beauty of chemical synthesis and organic chemistry. The ability to create such compounds in the lab opens pathways for drug development.

As you dive deeper into the world of flavonoids, it becomes clear that compounds like 4,5-dihydroxy-8-methoxy-2-phenyl-chromen-7-one are not just chemical entities; they represent a confluence of nature, chemistry, and health, making them a rich area of study for chemists and health professionals alike.