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Naringenin

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Identification
Molecular formula
C15H12O5
CAS number
480-41-1
IUPAC name
4,5,8-trihydroxy-2-phenyl-chromen-7-one
State
State

At room temperature, Naringenin is typically found as a solid. It is generally stable under normal conditions and is insoluble in water, but soluble in organic solvents such as ethanol and acetone.

Melting point (Celsius)
250.00
Melting point (Kelvin)
523.00
Boiling point (Celsius)
545.10
Boiling point (Kelvin)
818.20
General information
Molecular weight
272.26g/mol
Molar mass
272.2570g/mol
Density
1.3958g/cm3
Appearence

Naringenin is a colorless crystalline solid. It often appears as a powder and can form needle-like crystals when purified. The compound is typically odourless and exhibits a bitter taste. It is a flavonoid commonly found in citrus fruits.

Comment on solubility

Solubility of 4,5,8-Trihydroxy-2-phenyl-chromen-7-one

The solubility of 4,5,8-trihydroxy-2-phenyl-chromen-7-one, a compound often characterized by its phenolic and chromenone structures, is influenced by several factors. This compound exhibits varying solubility in different solvents:

  • Solvent Polarity: Due to its multiple hydroxyl groups, 4,5,8-trihydroxy-2-phenyl-chromen-7-one is generally more soluble in polar solvents such as water and methanol, as these solvents can interact favorably with the hydroxyl groups.
  • Hydrogen Bonding: The presence of hydroxyl (-OH) groups allows for significant hydrogen bonding with solvent molecules, further enhancing solubility in polar environments.
  • Organic Solvents: In juxtaposition, the compound's solubility in non-polar solvents like hexane is considerably lower, reflecting its hydrophilic nature.

It's noteworthy that, as with many polyhydroxylated compounds, the solubility may vary with temperature. Increasing temperature typically increases the solubility of solids in liquids, thus allowing for better dissolution of 4,5,8-trihydroxy-2-phenyl-chromen-7-one under heated conditions. Therefore, understanding the solubility profile of this compound is essential for its application in various chemical and pharmaceutical contexts.

Interesting facts

Interesting Facts about 4,5,8-Trihydroxy-2-phenyl-chromen-7-one

4,5,8-Trihydroxy-2-phenyl-chromen-7-one, often referred to as a type of flavonoid, is a fascinating compound that is a part of a larger family of polyphenolic compounds known for their wide array of biological activities. Here are some intriguing facts about this compound:

  • Bioactive Properties: This compound is celebrated for its significant antioxidant properties. Antioxidants are vital in combating oxidative stress, which is linked to various chronic diseases.
  • Medicinal Potential: Research indicates that flavonoids, including this compound, may have anti-inflammatory, antimicrobial, and even anticancer properties. Its potential application in pharmaceuticals opens exciting avenues for drug development.
  • Synthesis: The synthesis of 4,5,8-trihydroxy-2-phenyl-chromen-7-one can often be achieved through various pathways, including herbal extraction methods or synthetic organic chemistry techniques, illustrating the compound's versatility.
  • Natural Occurrence: This compound can be found in various plants, particularly in fruits and vegetables, which explains the health benefits commonly attributed to a diet rich in these foods.
  • Flavor and Fragrance: In addition to its medicinal properties, flavonoids can also contribute to the flavor and color of many fruits, enhancing their appeal and nutritional value.

With its diverse applications and promising health benefits, 4,5,8-trihydroxy-2-phenyl-chromen-7-one exemplifies the fascinating world of phytochemistry. Whether studied for its biological roles or incorporated into health products, this compound is an important element in the ongoing exploration of natural compounds in science.