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4,6-diiodo-2-(trifluoromethyl)-1H-benzimidazole

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Identification
Molecular formula
C8H3F3I2N2
CAS number
154268-41-4
IUPAC name
4,6-diiodo-2-(trifluoromethyl)-1H-benzimidazole
State
State

4,6-diiodo-2-(trifluoromethyl)-1H-benzimidazole is typically a solid at room temperature. It exists as a crystalline powder, stable and suitable for storage under usual laboratory conditions.

Melting point (Celsius)
252.00
Melting point (Kelvin)
525.15
Boiling point (Celsius)
337.00
Boiling point (Kelvin)
610.15
General information
Molecular weight
409.93g/mol
Molar mass
409.9310g/mol
Density
2.7000g/cm3
Appearence

The compound appears as a crystalline solid. Its color can range from off-white to a pale yellow, indicating the presence of iodine atoms within the structure. The solid nature allows it to be handled in standard laboratory conditions.

Comment on solubility

Solubility of 4,6-Diiodo-2-(trifluoromethyl)-1H-benzimidazole

The solubility of 4,6-diiodo-2-(trifluoromethyl)-1H-benzimidazole, often abbreviated as DITFB, presents unique characteristics worthy of exploration. Understanding its solubility is essential for applications in pharmaceuticals and materials science. Here are some key aspects:

  • Polarity: The presence of both iodine and trifluoromethyl groups in the structure contributes to its overall nonpolar character, which typically leads to lower solubility in polar solvents like water.
  • Solvent Compatibility: DITFB tends to be more soluble in organic solvents such as dimethyl sulfoxide (DMSO), acetone, and chloroform, where it can interact favorably due to similar polarities.
  • Temperature Effects: Solubility may increase with temperature, making higher temperatures potentially beneficial for dissolving this compound in appropriate solvents.
  • Applications: Due to its solubility profile, DITFB is often used in niche applications where solubility plays a crucial role, such as in developing specialized coatings or pharmaceuticals.

In conclusion, the solubility of 4,6-diiodo-2-(trifluoromethyl)-1H-benzimidazole is significantly dependent on the nature of the solvent and environmental conditions. Understanding these factors is vital for effectively utilizing this compound in various scientific fields.

Interesting facts

Interesting Facts about 4,6-Diiodo-2-(trifluoromethyl)-1H-benzimidazole

4,6-Diiodo-2-(trifluoromethyl)-1H-benzimidazole is a fascinating compound with unique properties and applications that intrigue both chemists and those in the pharmaceutical industry. Here are some key points that highlight its significance:

  • Structural Features: This compound features a benzimidazole core, which is an important scaffold in medicinal chemistry. The presence of two iodine atoms and a trifluoromethyl group enhances its reactivity and biological activity.
  • Biological Relevance: Compounds containing benzimidazole derivatives are known for their antimicrobial, antiviral, and anticancer properties. This makes them of high interest in drug development.
  • Halogen Effects: The introduction of halogen atoms, like iodine and fluorine, can significantly alter the electronic properties of the compound, affecting its interaction with biological targets and solvents.
  • Synthetic Pathways: The synthesis of this compound can involve diverse pathways, often requiring careful control of reaction conditions to ensure desired outcomes. This makes it a subject of study in synthetic organic chemistry.
  • Environmentally Friendly Applications: Due to its structure, this compound may be explored for its potential in environmentally friendly applications, such as being a part of agrochemicals or materials science.

As a chemist, the exploration of compounds like 4,6-diiodo-2-(trifluoromethyl)-1H-benzimidazole opens doors to discovering new therapeutic agents. With the ongoing research into its properties and potential applications, it remains a compound of interest in various scientific fields. “The future of chemistry lies in understanding the small nuances of compounds like these,” as many researchers claim.

Synonyms
BENZIMIDAZOLE, 4,6-DIIODO-2-(TRIFLUOROMETHYL)-
4,6-Diodo-2-(trifluoromethyl)benzimidazole
14689-57-7
DTXSID10163534
DTXCID3086025
FRJLBIMJFWZACZ-UHFFFAOYSA-N