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4,7-Dibromo-2-(trifluoromethyl)-1H-benzimidazole

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Identification
Molecular formula
C8H3Br2F3N2
CAS number
75147-34-5
IUPAC name
4,7-dibromo-2-(trifluoromethyl)-1H-benzimidazole
State
State

At room temperature, 4,7-Dibromo-2-(trifluoromethyl)-1H-benzimidazole is a solid.

Melting point (Celsius)
236.00
Melting point (Kelvin)
509.15
Boiling point (Celsius)
584.00
Boiling point (Kelvin)
857.15
General information
Molecular weight
359.92g/mol
Molar mass
359.8920g/mol
Density
2.2732g/cm3
Appearence

4,7-Dibromo-2-(trifluoromethyl)-1H-benzimidazole appears as a pale yellow crystalline solid. It is typically characterized by its molecular structure which includes bromine atoms and trifluoromethyl group substitutions, providing unique coloring and solid form.

Comment on solubility

Solubility of 4,7-Dibromo-2-(trifluoromethyl)-1H-benzimidazole

The solubility of 4,7-dibromo-2-(trifluoromethyl)-1H-benzimidazole is a topic of interest due to its unique structural properties. This compound, characterized by the presence of halogen substituents and a benzimidazole core, exhibits notable interactions with solvents. Here are some key points regarding its solubility:

  • Polarity: The trifluoromethyl group contributes to a certain level of polarity, which can affect how the compound interacts with various solvents.
  • Solvent Compatibility: Generally, such halogenated and nitrogen-containing compounds show better solubility in polar organic solvents, such as dimethyl sulfoxide (DMSO) and methanol.
  • Water Solubility: Due to its relatively bulky structure and multiple bromine atoms, 4,7-dibromo-2-(trifluoromethyl)-1H-benzimidazole is expected to have low solubility in water.
  • Influence of Substituents: The presence of electron-withdrawing groups can significantly influence solubility and should be considered when assessing the compound’s behavior in various media.

Overall, while precise solubility values may require experimental determination, the predictions based on the molecular structure indicate that 4,7-dibromo-2-(trifluoromethyl)-1H-benzimidazole will favor solubility in organic solvents rather than water.

Interesting facts

Interesting Facts about 4,7-Dibromo-2-(trifluoromethyl)-1H-benzimidazole

4,7-Dibromo-2-(trifluoromethyl)-1H-benzimidazole is a fascinating chemical compound that has sparked the interest of chemists and researchers in various fields. Here are some intriguing aspects of this compound:

  • Biomedical Potential: The unique structure of this compound suggests its potential as a pharmaceutical intermediate, particularly in drug development. Compounds with benzimidazole structures have been explored for their antimicrobial and antifungal properties.
  • Fluorine Chemistry: The presence of trifluoromethyl groups enhances the biological activity and metabolic stability of the compound. Compounds with fluorinated substituents often exhibit altered pharmacokinetic profiles, making them of great interest in medicinal chemistry.
  • Structural Versatility: The bromine atoms in the molecule contribute to its reactivity and can be useful in further synthetic transformations, allowing for the design of diverse derivatives.
  • Environmental Impact: Studying the environmental effects and degradation of this compound can provide insights into the impact of halogenated compounds on ecosystems, as halogens can influence the persistence of compounds in nature.
  • Research Applications: Due to its complex structure, 4,7-dibromo-2-(trifluoromethyl)-1H-benzimidazole serves as a useful reference compound in materials science, particularly in the development of new organic semiconductors.

In conclusion, the exploration of 4,7-dibromo-2-(trifluoromethyl)-1H-benzimidazole could lead to significant advancements in various scientific fields, offering numerous avenues for research and application. Its intriguing combination of features and properties makes it an essential subject for ongoing studies.

Synonyms
4228-97-1
BENZIMIDAZOLE, 4,7-DIBROMO-2-(TRIFLUOROMETHYL)-
BRN 0960436
4,7-Dibromo-2-(trifluoromethyl)benzimidazole
DTXSID30195110
5-23-06-00362 (Beilstein Handbook Reference)
DTXCID40117601
4,7-Dibromo-2-(trifluoromethyl)-1H-benzo[d]imidazole
DYLHVMDRWJVLSN-UHFFFAOYSA-N
AKOS003232046