Flavokawain B | Solubility of Things

Identification

Molecular formula

C₂₀H₂₁NO₄

CAS number

3420-72-2

IUPAC name

4,7-dihydroxy-8-(1-methyl-2-piperidyl)-2-phenyl-chromen-5-one

State

At room temperature, Flavokawain B is in a solid state. It is typically encountered in powdered form.

Melting point (Celsius)

230.00

Melting point (Kelvin)

503.15

Boiling point (Celsius)

548.20

Boiling point (Kelvin)

821.30

General information

Molecular weight

349.41g/mol

Molar mass

349.4090g/mol

Density

1.2380g/cm³

Appearence

Flavokawain B is a yellow crystalline solid. It is often observed as a powder with yellowish hues and has a distinct appearance under visible light.

Comment on solubility

Solubility of 4,7-Dihydroxy-8-(1-methyl-2-piperidyl)-2-phenyl-chromen-5-one

The solubility of the compound 4,7-dihydroxy-8-(1-methyl-2-piperidyl)-2-phenyl-chromen-5-one (C₂₀H₂₁NO₄) can be influenced by several factors. Understanding these influences is crucial for applications in pharmaceuticals, as solubility often affects bioavailability and efficacy. Here are some key considerations:

Polarity: The presence of hydroxyl groups (-OH) in the structure typically increases polarity, suggesting that this compound may have improved solubility in polar solvents such as water or alcohols.
Hydrogen Bonding: The ability of the hydroxyl groups to form hydrogen bonds with water molecules enhances the solubility of the compound in aqueous solutions.
Amine Group Interaction: The piperidyl moiety may also contribute to solubility through hydrogen bonding and dipole-dipole interactions with solvents.

However, it's essential to note that the overall solubility is likely dependent on the specific solvation environment. As a rule of thumb, "like dissolves like," meaning that:

If the solvent is polar, the solubility of this compound will likely be higher.
In non-polar solvents, the solubility may be significantly reduced due to lack of favorable interactions.

In conclusion, the solubility of this compound is expected to be moderate to high in polar solvents due to its functional groups, yet further empirical data would be beneficial for precise solubility assessments in specific conditions.

Interesting facts

Interesting Facts About 4,7-Dihydroxy-8-(1-methyl-2-piperidyl)-2-phenyl-chromen-5-one

This fascinating compound, known as 4,7-dihydroxy-8-(1-methyl-2-piperidyl)-2-phenyl-chromen-5-one, belongs to the class of flavonoids, which are renowned for their diverse biological activities. Here are some intriguing aspects of this compound:

Biological Activities: Compounds that contain the chromen-5-one structure have been studied for their anti-inflammatory, antioxidant, and anti-cancer properties. Research suggests that flavonoids play a crucial role in promoting health by modulating various cellular processes.
Pharmacological Potential: The presence of the piperidine ring enhances the potential for this compound to interact with biological targets. Studies have indicated that related piperidine derivatives may exhibit neuroprotective effects, which could be significant in the field of neuroscience.
Natural Sources: Flavonoids are commonly found in fruits, vegetables, and beverages like tea and red wine. These sources are often linked to reduced risks of chronic diseases, making it essential to explore the health benefits of compounds like this one.
Synthesis Versatility: The synthetic pathways leading to the formation of such compounds are of great interest. Organic chemists often develop novel methods to create flavonoid derivatives, which can lead to improved therapeutic agents.

The study of 4,7-dihydroxy-8-(1-methyl-2-piperidyl)-2-phenyl-chromen-5-one opens avenues to understanding the intricate connections between structure and function in pharmacology. As scientists continue to unravel the mechanisms of action of flavonoids, this compound exemplifies the fascinating intersection of chemistry and biology.