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Periplogenin

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Identification
Molecular formula
C19H22O
CAS number
569-62-8
IUPAC name
4b,8,8-trimethyl-5,6,7,8a,9,10-hexahydrophenanthren-3-ol
State
State
At room temperature, periplogenin is in a solid state, typically exhibiting its characteristic crystalline appearance.
Melting point (Celsius)
153.00
Melting point (Kelvin)
426.15
Boiling point (Celsius)
366.50
Boiling point (Kelvin)
639.70
General information
Molecular weight
286.39g/mol
Molar mass
286.3920g/mol
Density
1.0543g/cm3
Appearence

Periplogenin appears as a crystalline solid. It is typically white in color and has a standard crystalline structure common to many alcohols derived from phenanthrene.

Comment on solubility

Solubility of 4b,8,8-trimethyl-5,6,7,8a,9,10-hexahydrophenanthren-3-ol

The solubility of 4b,8,8-trimethyl-5,6,7,8a,9,10-hexahydrophenanthren-3-ol in various solvents can provide insight into its chemical behavior and potential applications. Typically, the solubility characteristics of such organic compounds are influenced by their molecular structure and hydrophobicity.

Key Solubility Insights:

  • Solvent Polarity: This compound is likely to have limited solubility in polar solvents such as water due to its large hydrocarbon structure, which contains multiple methyl groups and a phenanthrene backbone. Instead, it may exhibit higher solubility in non-polar solvents such as:
    • Hexane
    • Chloroform
    • Toluene
  • Hydrophobic Interactions: The presence of hydrophobic alkyl chains suggests that this compound will preferentially interact with non-polar environments.
  • Temperature Effects: As with many organic compounds, solubility may increase with temperature; however, specific empirical data would be needed to establish the extent of this effect.

In conclusion, while precise solubility data may not be readily available for 4b,8,8-trimethyl-5,6,7,8a,9,10-hexahydrophenanthren-3-ol, its chemical structure hints at a tendency towards >non-polar solubility<. Understanding these properties is crucial for applications in fields such as organic synthesis and materials science.

Interesting facts

Interesting Facts About 4b,8,8-trimethyl-5,6,7,8a,9,10-hexahydrophenanthren-3-ol

4b,8,8-trimethyl-5,6,7,8a,9,10-hexahydrophenanthren-3-ol is a fascinating compound with intricate molecular characteristics that make it a subject of interest in organic chemistry. Here are some noteworthy aspects:

  • Complex Structure: This compound features a polycyclic structure which includes six fused carbon rings. Such structures are often encountered in natural products and pharmaceuticals, providing intriguing avenues for exploration in synthesis and functional applications.
  • Biological Significance: Due to its specific hydroxyl group on the aromatic ring, this compound may possess unique biological activities, such as anti-inflammatory or antioxidant properties. Researchers are continually investigating its potential pharmaceutical applications.
  • Synthesis Challenges: The complexity of its molecular structure presents noteworthy challenges in synthetic chemistry. The multiple methyl groups and hexahydro configuration necessitate advanced synthetic techniques that can require a deep understanding of reaction mechanisms and stereochemistry.
  • Comparative Analysis: Compounds with similar structures, such as steroids and terpenoids, offer a rich comparative framework that advances our understanding of how minor structural changes can lead to significant variations in biological activity and chemical properties.
  • Natural Occurrence: Many compounds within this class can be derived from natural sources such as plants. Investigating natural analogs may lead to improved synthetic methods or inspire new bioactive drugs.

In summary, 4b,8,8-trimethyl-5,6,7,8a,9,10-hexahydrophenanthren-3-ol embodies the complexity and beauty of organic chemistry. Its intricate structure, potential biological activities, and the challenges associated with its synthesis make it a compelling subject of ongoing research and study.

Synonyms
PODOCARPA-8,11,13-TRIEN-12-OL
15340-76-8
DTXSID90934744
12-Methoxy-19-norpodocarpa-8,11,13-triene
3-Phenanthrenol, 4b,5,6,7,8,8a,9,10-octahydro-4b,8,8-trimethyl-, (4bS-trans)-
DTXCID201363386
DVRNZIIXOYTWET-UHFFFAOYSA-N
4b,8,8-trimethyl-5,6,7,8a,9,10-hexahydrophenanthren-3-ol
3-Phenanthrenol, 4b,5,6,7,8,8a,9,10-octahydro-4b,8,8-trimethyl-, (4bS,8aS)-