Interesting facts
Interesting Facts about (4R)-4-[(3R,5S,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
This remarkable compound belongs to the class of steroids and carries with it a wealth of intriguing characteristics:
- Structural Complexity: The structure of this compound features multiple chiral centers, which contributes to its unique three-dimensional configuration and biological activity.
- Biological Relevance: Due to its structural similarity to steroids, this compound may play a role in various biological processes, potentially influencing hormonal activity.
- Hydroxyl Groups: The presence of hydroxyl (–OH) groups in its structure can enhance both solubility and reactivity, making it an interesting candidate for biochemical studies.
- Potential Applications: Given its steroidal nature, this compound could have applications in pharmaceuticals, particularly in hormone replacement therapies or as anti-inflammatory agents.
In the realm of chemistry, understanding such compounds can lead to significant advancements:
- Drug Development: Research into compounds like this can aid in the development of targeted therapies for various diseases.
- Synthesis Techniques: The intricate synthesis of such a molecule presents challenges and opportunities in organic chemistry, pushing the boundaries of modern synthetic methods.
- Biological Impact Assessment: Studies focusing on its biological effects can unveil new insights into metabolic pathways and help in designing specific inhibitors.
As we continue exploring the intricacies of compounds like (4R)-4-[(3R,5S,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid, it's essential to appreciate their role in bridging the gap between organic chemistry and biological sciences.
Synonyms
chenodeoxycholic acid
Chenodiol
Chenic acid
Chenodesoxycholic acid
Cdca
Gallodesoxycholic acid
Chendol
Anthropodeoxycholic acid
Anthropodesoxycholic acid
Anthropododesoxycholic acid
Chenodesoxycholsaeure
Chenocol
Chenossil
Cholanorm
Xenbilox
Fluibil
Henohol
Chenique Acid
Chenocholic acid
3alpha,7alpha-Dihydroxy-5beta-cholan-24-oic acid
Acido chenodeoxicholico
Acide chenodeoxycholique
Acidum chenodeoxycholicum
7-alpha-Hydroxylithocholic acid
3alpha,7alpha-Dihydroxy-5beta-cholanic acid
7alpha-hydroxylithocholic acid
CCRIS 2195
3-alpha,7-alpha-Dihydroxycholanic acid
UNII-0GEI24LG0J
EINECS 207-481-8
0GEI24LG0J
3-alpha,7-alpha-Dihydroxycholansaeure
Acide chenodeoxycholique [INN-French]
Acido chenodeoxicholico [INN-Spanish]
Acidum chenodeoxycholicum [INN-Latin]
NSC 657949
acido quenodeoxicolico
DTXSID2020260
CHEBI:16755
Acid, Chenic
3-alpha,7-alpha-Dihydroxy-5-beta-cholan-24-oic acid
acide chenodesoxycholique
Cholan-24-oic acid, 3,7-dihydroxy-, (3alpha,5beta,7alpha)-
NSC-657949
NSC-757798
DTXCID40260
5-beta-Cholan-24-oic acid, 3-alpha,7-alpha-dihydroxy-
EC 207-481-8
Cholan-24-oic acid, 3,7-dihydroxy-, (3-alpha,5-beta,7-alpha)-
Leadiant (formerly Chenodeoxycholic acid sigma-tau)
Chenodal
CHENODEOXYCHOLIC ACID (MART.)
CHENODEOXYCHOLIC ACID [MART.]
Acid, Chenique
Acide chenodeoxycholique (INN-French)
Acido chenodeoxicholico (INN-Spanish)
Acidum chenodeoxycholicum (INN-Latin)
CHENODEOXYCHOLIC ACID (EP IMPURITY)
CHENODEOXYCHOLIC ACID [EP IMPURITY]
CHENODEOXYCHOLIC ACID (EP MONOGRAPH)
CHENODEOXYCHOLIC ACID [EP MONOGRAPH]
Acid, Chenodeoxycholic
Acid, Gallodesoxycholic
URSODEOXYCHOLIC ACID IMPURITY A (EP IMPURITY)
URSODEOXYCHOLIC ACID IMPURITY A [EP IMPURITY]
acido chenodesossicolico
chAnodAsoxycholique (acide)
A05AA01
3alpha,7alpha-Dihydroxycholanic acid
CHOLAN-24-OIC ACID, 3,7-DIHYDROXY-, (3alpha,5beta,7alpha)
207-481-8
474-25-9
Chenix
Chenodeoxycholate
Chenofalk
Chenodiol [USAN]
Chenodesoxycholsaeure [German]
(3alpha,5beta,7alpha)-3,7-dihydroxycholan-24-oic acid
CTEXLI
3-alpha,7-alpha-Dihydroxycholansaeure [German]
(4R)-4-[(3R,5S,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
Chenodeoxycholic acid [INN]
Chenodiol (USAN)
(3alpha,5beta,7alpha,8xi)-3,7-dihydroxycholan-24-oic acid
MFCD00064142
5beta-Cholanic acid-3alpha,7alpha-diol
Chenodeoxycholicacid
Chendeoxycholic Acid
24404-86-2
Chenocedon
Chendal
Chenodex
Chenorm
Hekbilin
Kebilis
Chenodeoxycholic acid; 3a,7a-dihydroxy-5ss-cholan-24-oic acid
NSC657949
NCGC00016387-02
CAS-474-25-9
JN3
chenodeoxycholic-acid
Cholan-24-oic acid, 3,7-dihydroxy-, (3a,5b,7a)-
(+)-chenodeoxycholate
CHENODIOL [MI]
Prestwick0_000285
Prestwick1_000285
Prestwick2_000285
Prestwick3_000285
Spectrum5_002009
CHENIX (TN)
CHENODIOL [VANDF]
(+)-chenodeoxycholic acid
bmse000908
7a-Hydroxy-desoxycholsaeure
BIDD:PXR0056
SCHEMBL25055
BSPBio_000190
GTPL608
MLS002154253
(3|A,5|A,7|A)-3,7-Dihydroxycholan-24-oic Acid
3a,7a-dihydroxy-5b-cholanate
SPBio_002409
BPBio1_000210
CHEMBL240597
Chenodeoxycholic acid, >=97%
CHENODIOL [ORANGE BOOK]
7.alpha.-Hydroxylithocholic acid
BDBM21674
Chenodeoxycholic Acid, Free Acid
3a,7a-dihydroxy-5b-cholanic acid
HMS1568J12
HMS2095J12
HMS2234I22
HMS3712J12
Chenodeoxycholic acid (JP16/INN)
Chenodeoxycholic acid (JP17/INN)
CHENODEOXYCHOLIC ACID [JAN]
Tox21_110412
Tox21_200491
US10208081, CDCA
(3beta,7beta,8xi,9xi,14xi,17alpha)-3,7-dihydroxycholan-24-oic acid
3a,7a-dihydroxy-5b-cholan-24-oate
Cholan-24-oic acid, 3,7-dihydroxy-, (3.alpha.,5.beta.,7.alpha.)-
HSCI1_000210
LMST04010032
AKOS024280614
CHENODEOXYCHOLIC ACID [WHO-DD]
CCG-220285
CS-0834
DB06777
FC09675
SMP1_000064
3.alpha.,7.alpha.-Dihydroxycholansaeure
3a,7a-dihydroxy-5b,14a,17b-cholanate
3a,7a-dihydroxy-5b-cholan-24-oic acid
NCGC00142400-03
NCGC00142400-04
NCGC00142400-08
NCGC00258045-01
(4R)-4-((1S,2S,7S,11S,5R,9R,10R,14R,15R)-5,9-dihydroxy-2,15-dimethyltetracyclo [8.7.0.0<2,7>.0<11,15>]heptadec-14-yl)pentanoic acid
3.alpha.,7.alpha.-Dihydroxycholanic acid
AS-13636
HY-76847
SMR000857194
3a,7a-dihydroxy-5b,14a,17b-cholanic acid
AB00513822
NS00069558
S1843
(3a,5b,7a)-3,7-dihydroxy-cholan-24-oate
3alpha, 7alpha-dihydroxy-5beta-cholanoic acid
EN300-75328
3a,7a-Dihydroxy-5b-cholan-24-oic acid;CDCA
3alpha, 7alpha,-dihydroxy-5beta-cholanic acid
C02528
D00163
(3a,5b,7a)-3,7-dihydroxy-cholan-24-oic acid
AB00513822-06
AB00513822_07
Q419028
3.alpha.,7.alpha.-Dihydroxy-5.beta.-cholanic acid
Dihydroxy-3.alpha.,7.alpha.(5.beta.)Cholanic acid
3.alpha.,7.alpha.-Dihydroxy-5.beta.-cholanoic acid
BRD-K18135438-001-14-2
BRD-K18135438-001-16-7
0DBBBC66-0CFA-4DB9-97F4-5B1492756A02
Z1172235745
3.alpha.,7.alpha.-Dihydroxy-5.beta.-cholan-24-oic acid
5.beta.-Cholan-24-oic acid, 3.alpha.,7.alpha.-dihydroxy-
(3alpha,5alpha,7beta,8alpha,17alpha)-3,7-dihydroxycholan-24-oic acid
3,7-Dihydroxycholan-24-oic acid, (3.alpha.,5.beta.,7.alpha.)- #
Chenodeoxycholic acid, 500 mug/mL in methanol, certified reference material
Chenodeoxycholic acid, European Pharmacopoeia (EP) Reference Standard
Cholan-24-oic acid, 3,7-dihydroxy-, (3-.alpha., 5-.beta., 7-.alpha.)-
Cholan-24-oic acid, 3,7-dihydroxy-, (3-alpha,5-beta,7-alpha)- (9CI)
CHOLAN-24-OIC ACID, 3,7-DIHYDROXY-, (3.ALPHA.,5.BETA.,7.ALPHA.)
(4R)-4-[(1R,3aS,3bR,4R,5aS,7R,9aS,9bS,11aR)-4,7-dihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]pentanoic acid
(4R)-4-[(1S,2S,5R,7S,9R,10R,11S,14R,15R)-5,9-dihydroxy-2,15-dimethyltetracyclo[8.7.0.0?,?.0??,??]heptadecan-14-yl]pentanoic acid
(4R)-4-[(1S,2S,5R,7S,9R,10R,11S,14R,15R)-5,9-dihydroxy-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecan-14-yl]pentanoic acid
(4R)-4-[(3R,5S,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoicacid
Solubility of (4R)-4-[(3R,5S,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
The solubility of organic compounds can vary significantly depending on their structure and functional groups present. In the case of (4R)-4-[(3R,5S,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid, it exhibits certain characteristics that are of interest:
In summary, while the compound may exhibit some degree of solubility due to its polar hydroxyl groups, the pronounced hydrophobic characteristics from the hydrocarbon composition could significantly limit its overall solubility in aqueous environments. Understanding the delicate balance between these factors is crucial for predicting the solubility behavior of such complex organic molecules.