Skip to main content

Morphine sulfate

ADVERTISEMENT
Identification
Molecular formula
C17H19NO3H2SO4
CAS number
64-31-3
IUPAC name
(4R,4aS,7R,12bR)-3-methyl-1,2,3,4,4a,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-3-ium-7,9-diol;sulfate
State
State

At room temperature, morphine sulfate is typically in the form of a solid crystalline structure or as a fine powder, depending on its preparation. It is commonly used in both oral and injectable pharmaceutical forms.

Melting point (Celsius)
254.00
Melting point (Kelvin)
527.15
Boiling point (Celsius)
197.00
Boiling point (Kelvin)
470.15
General information
Molecular weight
758.83g/mol
Molar mass
758.8330g/mol
Density
1.4900g/cm3
Appearence

Morphine sulfate is typically encountered as a white to off-white crystalline powder. It is often available in a form designed for pharmaceutical use, which may be compressed into tablets or dissolved for injection. The powder is odorless and has a bitter taste.

Comment on solubility

Solubility of (4R,4aS,7R,12bR)-3-methyl-1,2,3,4,4a,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-3-ium-7,9-diol; sulfate

The solubility of the compound (4R,4aS,7R,12bR)-3-methyl-1,2,3,4,4a,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-3-ium-7,9-diol sulfate (C17H19NO3H2SO4) can be characterized by several essential factors:

  • Polarity: The presence of charged sulfate groups typically enhances solubility in polar solvents, particularly water.
  • Hydrogen Bonding: The hydroxyl (OH) groups may participate in hydrogen bonding, further increasing solubility in aqueous environments.
  • Temperature Dependency: Solubility can vary with temperature; some compounds become more soluble as temperature increases.
  • pH Sensitivity: The solubility may also be influenced by the pH of the solution, as variations in acidity or basicity can affect ionization.

It is noteworthy that the compound's complex structure may lead to specific solubility characteristics, such as:

  • Higher solubility in polar solvents compared to non-polar solvents.
  • The potential for targeted delivery in pharmaceutical applications due to its unique interactions.

In summary, while the solubility of this compound in various solvents can provide significant insight into its utilization, the specific interactions and behaviors in solution warrant further investigation to understand its practical applications fully.

Interesting facts

Interesting Facts about (4R,4aS,7R,12bR)-3-methyl-1,2,3,4,4a,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-3-ium-7,9-diol; sulfate

This complex compound exhibits a fascinating structure and unique properties that make it a subject of interest in both organic chemistry and pharmacology. Here are some key points that highlight its significance:

  • Structural Complexity: The compound features a multi-fused ring system, typical of many natural products, which can lead to diverse biological activities.
  • Sulfate Group: The presence of a sulfate moiety suggests that the compound may interact with biological systems in specific ways, possibly through modulation of signaling pathways.
  • Potential Bioactivity: Compounds with such intricate structures are often bioactive, potentially serving as precursors for medicinal agents or standing as active pharmaceutical ingredients (APIs).
  • Nature-Inspired Design: The design and synthesis of compounds like this often draw inspiration from natural sources, reflecting the importance of bioactive compounds in drug development.
  • Aim for Therapeutic Use: It is intriguing to investigate how such compounds can be manipulated to enhance therapeutic efficacy or reduce side effects in medicinal chemistry.

Applications and Future Research

Given its structural features, future research might explore various applications, such as:

  1. Development of new pharmacological agents targeting specific health conditions.
  2. Investigations into antimicrobial or anticancer properties, considering the diverse functional groups that could interact with biological targets.
  3. Structure-Activity Relationship (SAR) studies to optimize activity based on the unique configuration of the compound.

In summary, the compound represents a vibrant intersection of chemistry and biology, inviting ongoing exploration into its potential effects and applications that could advance our understanding of medicinal chemistry.