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Erythromycin A

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Identification
Molecular formula
C37H67NO13
CAS number
114-07-8
IUPAC name
(4R,6R,7S,8S)-11-amino-8-(hydroxymethyl)-7-methoxy-12-methyl-2,5-diazatetracyclo[7.4.0.02,7.04,6]trideca-1(9),11-diene-10,13-dione
State
State
At room temperature, Erythromycin A is a solid.
Melting point (Celsius)
135.00
Melting point (Kelvin)
408.00
Boiling point (Celsius)
260.00
Boiling point (Kelvin)
533.00
General information
Molecular weight
733.94g/mol
Molar mass
733.9370g/mol
Density
1.3600g/cm3
Appearence

Erythromycin A appears as white or slightly yellow crystalline powder. It is known for its characteristic strong odor, often described as bitter. The powder can absorb moisture from the air, making it hygroscopic.

Comment on solubility

Solubility of (4R,6R,7S,8S)-11-amino-8-(hydroxymethyl)-7-methoxy-12-methyl-2,5-diazatetracyclo[7.4.0.02,7.04,6]trideca-1(9),11-diene-10,13-dione

The compound (4R,6R,7S,8S)-11-amino-8-(hydroxymethyl)-7-methoxy-12-methyl-2,5-diazatetracyclo[7.4.0.02,7.04,6]trideca-1(9),11-diene-10,13-dione exhibits unique solubility characteristics influenced by its complex structure. Understanding its solubility is crucial for applications in areas such as pharmacology and chemical synthesis.

Factors Affecting Solubility

Some important factors that influence the solubility of this compound include:

  • Polarity: The presence of multiple functional groups such as amino and hydroxymethyl affects its interaction with polar solvents.
  • Molecular Weight: Its relatively high molecular weight may decrease solubility in certain solvents.
  • Hydrogen Bonding: The ability to form hydrogen bonds can enhance solubility in water.
  • pH Levels: The solubility may vary significantly based on the pH, especially due to the presence of the amino group which can become protonated.

General Insights

In general, compounds with similar structural features often show solubility patterns such as:

  • Soluble in: Polar solvents (water, methanol) when hydrogen bonding is favorable.
  • Insoluble in: Non-polar solvents (hexane, benzene) due to lack of significant interactions.

As a result, the solubility of this tetracyclic compound can be regarded as moderate, with a tendency to be more soluble in polar environments. Further experimental evaluations would provide concrete insights into its solubility behavior across various solvents.


Interesting facts

Interesting Facts About (4R,6R,7S,8S)-11-amino-8-(hydroxymethyl)-7-methoxy-12-methyl-2,5-diazatetracyclo[7.4.0.02,7.04,6]trideca-1(9),11-diene-10,13-dione

This intriguing compound is a rich member of the diazatetracyclic family, showcasing a complex and fascinating molecular architecture. Below are some of the key highlights about this compound:

  • Unique Structural Arrangement: The presence of four distinct rings in its structure contributes to its significant biological activity. The tetracyclic structure allows for various conformations, which can influence its interactions with biological systems.
  • Biological Relevance: Compounds with similar structures are often investigated for their potential pharmacological activities. They might exhibit properties such as antimicrobial, anti-inflammatory, or even anticancer effects, making them of great interest in medicinal chemistry.
  • Functional Groups: This compound possesses crucial functional groups, namely the amino and hydroxymethyl groups. These groups can enhance its reactivity and enable it to engage in crucial biological interactions.
  • Chirality: With its specific stereochemistry indicated by the (4R,6R,7S,8S) configuration, chirality plays a vital role in the activity of this compound. In the realm of drug design, enantiomers can have drastically different biological effects.
  • Potential Applications: Researchers are exploring compounds with similar frameworks for applications in drug development. The exploration of structure-activity relationships (SAR) can lead to the discovery of novel therapeutics.

In summary, the compound's intricate design and potential biological implications make it a noteworthy subject of study in the field of chemistry. As you delve deeper into its properties and functions, one cannot help but appreciate the beauty and complexity of organic molecules in the realm of science!

Synonyms
SCHEMBL29367564
DTXSID80949701
6-Amino-8-(hydroxymethyl)-8a-methoxy-5-methyl-1,1a,2,8,8a,8b-hexahydroazireno[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione