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Dexamethasone Acetate

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Identification
Molecular formula
C24H31FO6
CAS number
1177-87-3
IUPAC name
[(4R,8S,19S)-8-acetyl-19-fluoro-11-hydroxy-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icos-17-en-16-yl] acetate
State
State

At room temperature, dexamethasone acetate is in a solid state, specifically a crystalline powder.

Melting point (Celsius)
240.00
Melting point (Kelvin)
513.00
Boiling point (Celsius)
392.80
Boiling point (Kelvin)
666.00
General information
Molecular weight
434.50g/mol
Molar mass
462.5180g/mol
Density
1.3100g/cm3
Appearence
Dexamethasone acetate presents as a white to practically white crystalline powder.
Comment on solubility

Solubility Characteristics

The solubility of [(4R,8S,19S)-8-acetyl-19-fluoro-11-hydroxy-6,6,9,13-tetramethyl-5,7-dioxapentacyclo10.8.0.02,9.04,8.013,18]icos-17-en-16-yl] acetate can be quite complex due to its unique structure and functional groups.

This compound exhibits a range of solubility behaviors based on several factors:

  • Polarity: The presence of polar functional groups, such as hydroxyl and acetate, suggests potential for solubility in polar solvents like water.
  • Hydrophobic Regions: The sizable hydrophobic parts of the molecule may limit solubility in water but enhance solubility in organic solvents such as ethanol or dichloromethane.
  • Temperature Dependency: Solubility can also be temperature-dependent, often increasing with rising temperatures in many solvents.
  • Interactions: The compound's interaction with specific solvents can lead to varied solubility profiles, which can be influenced by solvent characteristics such as dielectric constant and ability to form hydrogen bonds.

Overall, while one might find it difficult to generalize the solubility of this compound, laboratory tests in varied solvents are essential for determining its precise solubility profile. Thus, researchers are encouraged to explore various solvent systems to fully understand the solubility of this intricate molecular structure.

Interesting facts

Interesting Facts About [(4R,8S,19S)-8-acetyl-19-fluoro-11-hydroxy-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icos-17-en-16-yl] Acetate

This intricate compound, known for its unique structure, reveals a fascinating intersection of chemistry, biology, and medicinal applications. Here are some intriguing aspects:

  • Complex Molecular Structure: The compound features a pentacyclic framework, showcasing how nature often employs complex architectures to create bioactive molecules.
  • Stereochemistry: With specific stereocenters denoted by the (4R, 8S, 19S) configuration, this compound serves as an example of the importance of stereochemistry in drug design, influencing biological activity and therapeutic efficacy.
  • Fluorine Incorporation: The inclusion of fluorine in the structure is noteworthy. Fluorine can enhance metabolic stability and influence lipophilicity, making it a valuable element in pharmaceutical chemistry.
  • Potential Applications: Due to its structural characteristics, compounds like this one are often investigated for their potential as therapeutic agents in treating various diseases, including cancer and infectious diseases.
  • Natural Products Inspiration: Many compounds of this complexity are inspired by natural products, highlighting the collaborative relationship between chemistry and biology. The research into similar biosynthetic pathways can lead to the discovery of novel drug candidates.

In summary, the compound represents not only a fascinating chemical entity but also signifies the broader implications of structural chemistry in the development of new therapeutic agents. As researchers delve deeper into its properties and potential, this compound exemplifies the continuous exploration within the field of medicinal chemistry.