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Drospirenone

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Identification
Molecular formula
C24H30Cl2O3
CAS number
67392-87-4
IUPAC name
(4R,9'R)-9',11'-dichloro-2,2,10',13'-tetramethyl-spiro[1,3-dioxane-4,17'-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthrene]-3',5-dione
State
State
Drospirenone is a solid compound at room temperature. It is used widely in pharmaceuticals and is not easily volatile.
Melting point (Celsius)
196.00
Melting point (Kelvin)
469.15
Boiling point (Celsius)
465.40
Boiling point (Kelvin)
738.60
General information
Molecular weight
366.49g/mol
Molar mass
366.4930g/mol
Density
1.2906g/cm3
Appearence

Drospirenone appears as a white or almost white crystalline powder. It is commonly used in various pharmaceutical applications, such as oral contraceptives.

Comment on solubility

Solubility of (4R,9'R)-9',11'-dichloro-2,2,10',13'-tetramethyl-spiro[1,3-dioxane-4,17'-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthrene]-3',5-dione

The solubility of the compound (4R,9'R)-9',11'-dichloro-2,2,10',13'-tetramethyl-spiro[1,3-dioxane-4,17'-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthrene]-3',5-dione is a complex topic, primarily due to its intricate molecular structure and functional groups. Solubility can greatly depend on various factors, including:

  • Polarity: The presence of polar groups can facilitate solubility in polar solvents such as water.
  • Hydrophobic regions: If the compound has significant hydrophobic parts, it may exhibit higher solubility in organic solvents like chloroform or ethanol.
  • Temperature: Increasing temperature generally enhances solubility, particularly for solid compounds.
  • Interactions: Hydrogen bonding and van der Waals forces can influence solubility in different solvents.

As such, the solubility of this compound may be quite selective in nature. It is likely to be poorly soluble in water, but potentially more soluble in non-polar or less polar organic solvents. However, specific experimental data would be essential to confirm these predictions and determine the actual solubility characteristics of this compound.

Interesting facts

Interesting Facts about (4R,9'R)-9',11'-dichloro-2,2,10',13'-tetramethyl-spiro[1,3-dioxane-4,17'-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthrene]-3',5-dione

This compound, with its intricate structure, showcases the fascinating world of organic chemistry. Here are some interesting aspects of this unique molecule:

  • Complex Structure: The molecule features a spiro configuration, which is characterized by two rings that share a single common atom. This complexity allows for unique interactions and properties in organic reactions.
  • Dichloro Substituents: The presence of two chlorine atoms significantly influences the reactivity and properties of the compound, often enhancing its ability to participate in various chemical reactions, including nucleophilic substitutions.
  • Applications in Research: Due to its unique structure, compounds like this one are often analyzed for their potential applications in medicinal chemistry and materials science. Researchers are particularly interested in how modifications to such structures can lead to novel therapeutic agents.
  • Stability and Reactivity: The incorporation of multiple methyl groups in the structure contributes to the stability of the molecule. Such stability can be crucial for the development of new synthetic routes in organic synthesis.
  • Visualizing Complexity: The spiro compound structure exemplifies the diversity of molecular architecture that chemists encounter. Visualizing and understanding such complex 3D arrangements is essential for predicting chemical behavior and reactivity.

Incorporating such intricate structures into a chemistry curriculum not only enhances students' understanding of stereochemistry but also emphasizes the importance of structural nuances in determining molecular properties. As _Albert Einstein_ famously said, "Everything should be made as simple as possible, but no simpler." This compound stands as a reminder of the beauty found in complexity within the realm of chemistry.