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Sanguinarine Nitrate

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Identification
Molecular formula
C20H14N2O4
CAS number
2447-54-3
IUPAC name
(4S,12bS)-7,9-dimethoxy-3-methyl-1,2,3,4,7a,13-hexahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-3-ium;(3,5-dinitro-4-oxo-cyclohexa-2,5-dien-1-ylidene)-dioxido-ammonium
State
State

At room temperature, sanguinarine nitrate is in a solid state, typically in the form of a dry crystalline powder.

Melting point (Celsius)
284.00
Melting point (Kelvin)
557.15
Boiling point (Celsius)
662.00
Boiling point (Kelvin)
935.15
General information
Molecular weight
334.33g/mol
Molar mass
334.3330g/mol
Density
1.4210g/cm3
Appearence

Sanguinarine appears as an orange crystalline powder. It is often used professionally in laboratories for various chemical applications and has a strong coloration.

Comment on solubility

Solubility of (4S,12bS)-7,9-dimethoxy-3-methyl-1,2,3,4,7a,13-hexahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-3-ium;(3,5-dinitro-4-oxo-cyclohexa-2,5-dien-1-ylidene)-dioxido-ammonium

The solubility of the compound (4S,12bS)-7,9-dimethoxy-3-methyl-1,2,3,4,7a,13-hexahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-3-ium;(3,5-dinitro-4-oxo-cyclohexa-2,5-dien-1-ylidene)-dioxido-ammonium can be influenced by several factors:

  • Polarity: As the compound contains both hydrophobic (non-polar) and hydrophilic (polar) regions, its solubility may vary greatly depending on the solvent used.
  • Temperature: Increased temperature generally enhances solubility for many solids. However, the specific behavior should be confirmed experimentally.
  • pH Levels: The presence of ionic functional groups may affect solubility in aqueous solutions, making it pH-dependent.

In water, the solubility could potentially be limited due to the compound's complex structure and hydrophobic portions. As a rule of thumb, compounds that have aromatic and alkyl groups often exhibit lower solubility in polar solvents like water, while they may become soluble in organic solvents such as ethanol or DMSO.

It is crucial to conduct solubility testing under various conditions to achieve a comprehensive understanding, as stated: "Solubility is often best assessed in the environment in which it is intended to function." This highlights the importance of context in determining a compound's solubility characteristics.

Interesting facts

Interesting Facts about (4S,12bS)-7,9-dimethoxy-3-methyl-1,2,3,4,7a,13-hexahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-3-ium; (3,5-dinitro-4-oxo-cyclohexa-2,5-dien-1-ylidene)-dioxido-ammonium

This remarkable compound is a fascinating example of chemical ingenuity, showcasing the intricate architecture and diverse functionalities present in organic chemistry. Here are some intriguing aspects:

  • Complex Structure: The combination of isoquinoline morphology and multiple functional groups illustrates the sophisticated design of this compound, which is crucial for its potential applications in medicinal chemistry.
  • Biological Significance: Compounds with this structure have been studied for their biological activity, which could range from anti-cancer properties to psychological effects, making them an interesting subject for pharmacological research.
  • Electron-Deficient Characteristics: The presence of dinitro and oxo groups imparts unique electron-withdrawing capabilities, which can significantly influence the reactivity and stability of the compound, opening up avenues for further synthetic modifications.
  • Application in Synthesis: Due to its structural elements, this compound may serve as a versatile precursor or building block in synthesizing more complex chemical entities, which is vital for developing novel drugs.

As noted by chemists engaged in studying such compounds, *“Understanding the nuanced behavior of complex organic molecules not only unravels their potential but also enriches our knowledge of chemical interactions.”*

In summary, this compound stands at the intersection of **synthetic creativity** and **biological innovation**, emphasizing the importance of continuous exploration in the realm of chemical sciences.