Skip to main content

Salvinorin A

ADVERTISEMENT
Identification
Molecular formula
C23H28O8
CAS number
83729-01-5
IUPAC name
(4S,12bS)-9-methoxy-1,2,3,4,4a,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-ol
State
State
Salvinorin A is typically found as a solid at room temperature, often in a crystalline form that is stable under normal conditions.
Melting point (Celsius)
238.00
Melting point (Kelvin)
511.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
432.47g/mol
Molar mass
432.4710g/mol
Density
1.2500g/cm3
Appearence
Salvinorin A appears as a fine crystalline powder. It is usually white to off-white in color, although impurities might impart a slight beige appearance.
Comment on solubility

Solubility of (4S,12bS)-9-methoxy-1,2,3,4,4a,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-ol

The solubility of (4S,12bS)-9-methoxy-1,2,3,4,4a,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-ol is an intriguing topic due to its complex structure. Understanding its solubility characteristics can provide insights into its potential applications and behavior in various environments.

In general, the solubility of compounds such as this can be influenced by several factors:

  • Polarity: The presence of methoxy (-OCH3) and hydroxyl (-OH) groups suggests that the compound may exhibit some level of polarity, potentially increasing solubility in polar solvents like water.
  • Hydrophobic regions: Conversely, the larger hydrophobic portions of the molecule might hinder solubility in purely polar solvents, leading to a preferential solubility in less polar organic solvents.
  • Temperature: Temperature changes can greatly affect solubility, with many compounds becoming more soluble at elevated temperatures.
  • pH levels: The pH of the solvent can influence the protonation state of the hydroxyl group, which could either enhance or reduce solubility in solutions.

As a general note, “solubility can be viewed as a balance between attractive and repulsive forces between the solute and solvent molecules.” Therefore, for (4S,12bS)-9-methoxy-1,2,3,4,4a,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-ol, empirical testing will be crucial for determining its actual solubility in various environments.

In summary, the solubility of this compound is likely to vary significantly based on its chemical structure and the conditions under which it is analyzed. Understanding these nuances is essential for further research and applications.

Interesting facts

Interesting Facts about (4S,12bS)-9-methoxy-1,2,3,4,4a,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-ol

This compound is a fascinating member of the class of natural alkaloids, often recognized for its complex structure and potential biological activity. It belongs to a unique category of isoquinoline derivatives, which are known for their diverse range of pharmacological effects.

1. Structure and Chemistry

The intricate structure of this compound features:

  • Multiple Rings: Comprising several interconnected rings, the molecular architecture is a hallmark of many bioactive compounds.
  • Stereochemistry: The specification of (4S,12bS) indicates a high level of stereochemical complexity, which plays a crucial role in its interaction with biological systems.
  • Functional Groups: The presence of a methoxy group enhances its lipophilicity, potentially influencing its pharmacokinetics.

2. Biological Significance

Compounds like this one have been studied for their potential therapeutic roles:

  • Antimicrobial Properties: Isoquinoline derivatives are often associated with antimicrobial activity, making them candidates for further exploration in drug development.
  • Neurological Effects: Research suggests some compounds in this family may exhibit neuroprotective effects, thus offering possibilities in treating neurodegenerative diseases.

3. Research and Applications

The exploration into compounds such as (4S,12bS)-9-methoxy-1,2,3,4,4a,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-ol is ongoing, and scientists are excited about:

  • Drug Development: Its novel structure may lead to the synthesis of new drugs with enhanced efficacy and specificity.
  • Natural Product Chemistry: The compound serves as an inspiration in the field of natural product synthesis, where chemists seek to replicate or modify its structure to create derivatives with improved properties.

In conclusion, (4S,12bS)-9-methoxy-1,2,3,4,4a,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-ol embodies a rich field of study, bridging chemistry with biology and medicine, and highlighting the importance of complex molecules in the pursuit of new therapeutic agents.