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Codeine acetate

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Identification
Molecular formula
C19H24NO4
CAS number
41444-62-6
IUPAC name
(4S,4aR,7S,7aR,12bS)-3-methyl-1,2,3,4,4a,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-3-ium-7,9-diol;acetate
State
State

At room temperature, codeine acetate typically exists as a solid. Its crystalline structure makes it a stable and non-volatile compound under standard laboratory conditions.

Melting point (Celsius)
154.50
Melting point (Kelvin)
427.65
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.15
General information
Molecular weight
371.43g/mol
Molar mass
371.4300g/mol
Density
1.3400g/cm3
Appearence

Codeine acetate appears as a white or off-white crystalline powder. It is characterized by its fine, fluffy texture and is often seen as quite pure and bright in visual assessments.

Comment on solubility

Solubility of (4S,4aR,7S,7aR,12bS)-3-methyl-1,2,3,4,4a,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-3-ium-7,9-diol;acetate

The solubility of complex organic compounds like (4S,4aR,7S,7aR,12bS)-3-methyl-1,2,3,4,4a,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-3-ium-7,9-diol;acetate can vary significantly based on a variety of factors. Here are some key points to consider:

  • Polarity: The presence of hydroxyl (-OH) groups typically increases polarity, enhancing solubility in polar solvents such as water.
  • Hydrogen Bonding: Hydrogen bonding between the compound's functional groups and solvent molecules can play a crucial role in solubility.
  • Temperature: Solubility may increase with temperature, allowing for greater dissolution of the compound in a solvent.
  • Solvent Compatibility: The choice of solvent is critical; nonpolar solvents may not adequately dissolve polar compounds, while polar solvents can be more effective.
  • Complex Formation: The formation of complexes with solvent molecules can also affect solubility.

As a result, one might say that "the solubility of this compound is not just about what it is, but also about where it is placed." Understanding these interactions can lead to improved formulations and applications in various fields, including pharmaceuticals.

Interesting facts

Interesting Facts about the Compound (4S,4aR,7S,7aR,12bS)-3-methyl-1,2,3,4,4a,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-3-ium-7,9-diol;acetate

This intriguing compound belongs to a class of chemicals known for their complex structures and diverse properties. Its detailed stereochemistry, represented by a series of specific stereocenters, highlights the importance of chiral centers in determining the behavior and functionality of molecules in biological systems.

Key Aspects of This Compound:

  • Multifunctional Potential: With its numerous hydroxy and methoxy groups, this molecule exhibits potential for various biological activities, possibly acting as a pharmacophore in drug development.
  • Sustainable Chemistry: Being a naturally derived or synthetically altered compound, it opens avenues for research into green chemistry methods for synthesis and extraction, minimizing environmental impact.
  • Structure-Activity Relationship (SAR): The particular arrangement of atoms can lead to vastly different biological activities, emphasizing how slight modifications can have significant implications in medicinal chemistry.
  • Historical Context: Compounds of this complexity might be inspired by ancient medicinal practices, showcasing how traditional medicine can influence modern pharmacology.

Furthermore, this compound is indicative of a broader area of inquiry within organic chemistry, especially as scientists explore the process of total synthesis of complex natural products. As highlighted by many researchers, "The beauty of synthetic organic chemistry lies in the challenges of constructing complex molecules, teasing apart their intrinsic properties, and unlocking their potential." This compound is no exception, serving as a reminder of the intricate dance between structure and function in the realm of chemistry.

In conclusion, the study of such a complex compound not only enriches our understanding of molecular design but also encourages innovative applications in health, industry, and sustainability.