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morphine

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Identification
Molecular formula
C17H19NO3
CAS number
57-27-2
IUPAC name
(4S,4aS,12bS)-4a-hydroxy-9-methoxy-3-methyl-2,4,7a,13-tetrahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one
State
State

At room temperature, morphine is typically found as a solid, often in crystalline or powdered form.

Melting point (Celsius)
254.00
Melting point (Kelvin)
527.15
Boiling point (Celsius)
200.00
Boiling point (Kelvin)
473.15
General information
Molecular weight
285.34g/mol
Molar mass
285.3380g/mol
Density
1.3400g/cm3
Appearence

Morphine is generally in the form of colorless crystals or a white crystalline powder. It may have a glossy appearance when in crystal form.

Comment on solubility

Solubility of (4S,4aS,12bS)-4a-hydroxy-9-methoxy-3-methyl-2,4,7a,13-tetrahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one

The solubility of (4S,4aS,12bS)-4a-hydroxy-9-methoxy-3-methyl-2,4,7a,13-tetrahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one can be influenced by several factors, making it an interesting compound to explore in terms of its interactions with solvents.

Key Factors Affecting Solubility:

  • Polarity of the Solvent: This compound's complex structure suggests varying levels of polarity which may affect solubility in polar versus non-polar solvents.
  • Hydrogen Bonding: The presence of hydroxyl groups may facilitate hydrogen bonding, potentially enhancing solubility in polar solvents such as water.
  • Temperature: Elevated temperatures often increase solubility for many organic compounds, a factor to consider in practical applications.
  • pH Levels: As the compound contains functional groups sensitive to changes in pH, this can also significantly affect solubility due to ionization.

In general, hydrophobic compounds typically display low solubility in water but can be more soluble in organic solvents. Conversely, hydrophilic compounds tend to be more soluble in aqueous environments. The solubility profile of (4S,4aS,12bS)-4a-hydroxy-9-methoxy-3-methyl-2,4,7a,13-tetrahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one may thus depend heavily on the choice of solvent and the specific conditions under which solubility is assessed.

Ultimately, understanding the solubility characteristics of this compound is crucial for its effective application in various fields, including pharmaceuticals and organic chemistry.

Interesting facts

Interesting Facts about (4S,4aS,12bS)-4a-hydroxy-9-methoxy-3-methyl-2,4,7a,13-tetrahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one

This compound is a fascinating member of the alkaloid family, specifically known for its complex structure and potential biological activities. Alkaloids, in general, are notorious for their pharmacological effects and have been the subject of extensive research in medicinal chemistry.

Here are some intriguing aspects of this compound:

  • Structural Complexity: The intricate arrangement of functional groups in this molecule suggests rich stereochemistry, which can play a significant role in its biological interactions.
  • Potential Therapeutic Uses: Compounds with similar structures are often investigated for their effects in treating various diseases, including cancer and neurological disorders. The presence of the hydroxyl and methoxy groups is often linked to enhanced bioactivity.
  • Natural Product Chemistry: This compound could be derived from natural sources, indicating a need for studies focusing on its biosynthesis and ecological roles within particular organisms.
  • Research Interest: The scientific community is highly interested in understanding how structural modifications can enhance or alter the pharmacological profiles of such complex molecules.

As a chemistry student or researcher, delving into compounds like this offers a myriad of opportunities for discovery and innovation. The balance between structure and function in organic molecules is crucial, and studying such compounds helps unravel the complicated puzzle of their biological activities. Indeed, the exploration of (4S,4aS,12bS)-4a-hydroxy-9-methoxy-3-methyl-2,4,7a,13-tetrahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one could lead to significant advancements in both chemistry and pharmacology.