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Chelidonine

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Identification
Molecular formula
C20H23NO5
CAS number
476-32-4
IUPAC name
(4S,4aS,7aS,12bS)-3-methyl-7-methylene-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,9-diol
State
State

At room temperature, Chelidonine is in a solid state. It is typically found as a crystalline powder.

Melting point (Celsius)
135.50
Melting point (Kelvin)
408.65
Boiling point (Celsius)
394.00
Boiling point (Kelvin)
667.15
General information
Molecular weight
353.43g/mol
Molar mass
353.4260g/mol
Density
1.2968g/cm3
Appearence

Chelidonine is typically a colorless crystalline solid. However, it may also appear in various shades ranging from pale yellow to white, depending on purity and form. Its crystalline nature is evident under a microscope, with clear and well-defined crystal structures.

Comment on solubility

Solubility of (4S,4aS,7aS,12bS)-3-methyl-7-methylene-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,9-diol

The *solubility* of a compound can significantly impact its practical applications, pharmacological behavior, and environmental fate. In the case of (4S,4aS,7aS,12bS)-3-methyl-7-methylene-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,9-diol, the nature and structure of the compound suggest several key points regarding its solubility:

  • Polarity: The presence of hydroxyl (-OH) groups in the structure indicates potential for hydrogen bonding, which typically enhances solubility in polar solvents, such as water.
  • Hydrocarbon Chains: The methylene and methyl groups may contribute a hydrophobic character, which could diminish solubility in highly polar solvents but may result in better solubility in organic solvents.
  • Structural Complexity: The intricate structure could lead to unique solubility characteristics, possibly affecting bioavailability in pharmaceutical contexts.
  • Experimental Validation: As always, empirical testing is crucial since theoretical predictions can be limited by various factors including molecular interactions and crystallinity.

In summary, while the combination of polar and non-polar functionalities in the compound suggests an intriguing solubility profile, determining the exact solubility requires experimental data to draw definitive conclusions. It is imperative to test solubility in various solvents to better understand the behavior of this complex molecule.

Interesting facts

Interesting Facts About (4S,4aS,7aS,12bS)-3-methyl-7-methylene-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,9-diol

This fascinating compound belongs to the class of alkaloids, which are naturally occurring organic compounds that mostly contain basic nitrogen atoms. Alkaloids are renowned for their significant effects on living organisms and are often used in medicine.

  • Structural Complexity: The structure of this compound is intricate, featuring multiple chiral centers. The stereochemistry is critical as it influences the biological activity and pharmacokinetics of the compound.
  • Potential Applications: Compounds of this nature have shown potential in medicinal chemistry due to their ability to interact with various biological receptors, making them of interest for drug development.
  • Natural Sources: Many alkaloids are derived from plants, and the inspiration for synthetic versions often comes from traditional herbal remedies. This specific compound may find its parallels in the study of natural products.
  • Chemical Reactivity: The presence of methylene and hydro groups adds to its chemical reactivity, providing various pathways for further functionalization in synthetic chemistry.

As scientists continue to investigate the properties and applications of such compounds, we can expect exciting developments in fields such as pharmacology and organic synthesis. As commented by one renowned chemist, "Nature often holds the keys to innovation in drug discovery." This compound exemplifies such synergy of nature and science.