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5-(1-piperidylmethyl)benzofuran-2-carboxamide

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Identification
Molecular formula
C16H18N2O2
CAS number
172026-03-6
IUPAC name
5-(1-piperidylmethyl)benzofuran-2-carboxamide
State
State

At room temperature, the compound is in a solid state, typically seen as a crystalline powder.

Melting point (Celsius)
181.00
Melting point (Kelvin)
454.15
Boiling point (Celsius)
453.00
Boiling point (Kelvin)
726.15
General information
Molecular weight
270.33g/mol
Molar mass
270.3350g/mol
Density
1.2405g/cm3
Appearence

5-(1-piperidylmethyl)benzofuran-2-carboxamide is typically a white to off-white crystalline solid. The compound is often found in powdered form.

Comment on solubility

Solubility of 5-(1-piperidylmethyl)benzofuran-2-carboxamide

The solubility of 5-(1-piperidylmethyl)benzofuran-2-carboxamide can be influenced by various factors, including its molecular structure and the solvents in which it is dissolved. This compound, characterized by its complex structure, often exhibits moderate solubility in organic solvents. Here are some key points to consider regarding its solubility:

  • Polar solvents: The presence of polar functional groups may provide some degree of solubility in polar solvents such as water, albeit often at low concentrations.
  • Non-polar solvents: It is likely to be more soluble in non-polar organic solvents like dichloromethane or ethyl acetate due to its aromatic system.
  • Temperature effect: As with many organic compounds, increasing the temperature can enhance solubility, allowing for greater solubility in various solvents.
  • pH influence: The solubility may also vary with the pH of the solution, especially if ionizable groups are present, leading to better solubility in basic or acidic conditions.

Overall, solubility is a crucial factor to consider when studying the behavior of 5-(1-piperidylmethyl)benzofuran-2-carboxamide in various chemical and biological systems. Determining the ideal solvent for dissolution can significantly impact its applications and interactions in research and industry.

Interesting facts

Interesting Facts about 5-(1-Piperidylmethyl)benzofuran-2-carboxamide

5-(1-Piperidylmethyl)benzofuran-2-carboxamide is an intriguing chemical compound that attracts considerable interest within the realms of medicinal chemistry and pharmacology. Here are some notable facts:

  • Pharmacological Potential: This compound has shown promise in various studies for its potential use in treating neurological disorders and could act as a *novel therapeutic agent*.
  • Structure-Activity Relationship: The presence of the piperidine ring significantly influences the biological activity of the molecule, allowing chemists to explore modifications that improve efficacy.
  • Analog Synthesis: This compound serves as a vital scaffold for synthesizing analogs, which can be tailored to enhance selectivity and minimize side effects for targeted therapies.
  • Multi-faceted Applications: Beyond its potential in drug development, 5-(1-Piperidylmethyl)benzofuran-2-carboxamide may also have applications in materials science or as a starting point for the synthesis of complex molecules.

The exploration of 5-(1-piperidylmethyl)benzofuran-2-carboxamide demonstrates the importance of structural diversity in medicinal chemistry, leading to enriched knowledge about pharmacodynamics and the pursuit of effective therapies. In the words of renowned chemist Linus Pauling, "The best way to have a good idea is to have a lot of ideas." This principle rings true as researchers continue to innovate and develop compounds like this one.

In summary, the compounds such as 5-(1-piperidylmethyl)benzofuran-2-carboxamide exemplify how small molecular modifications can open up a wide array of biological functions and therapeutic avenues.

Synonyms
5-(N-Piperidinomethyl)coumarylamide
6115-97-5
2-BENZOFURANCARBOXAMIDE, 5-(PIPERIDINOMETHYL)-
L 4035
2-Benzofurancarboxamide, 5-(1-piperidinylmethyl)-
NSC 85432
BRN 1623317
NCIOpen2_005002
5-20-03-00423 (Beilstein Handbook Reference)
DTXSID80210044
NSC85432
NSC-85432
WLN: T56 BOJ CVZ G1- AT6NTJ