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Tetrahydroberberine

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Identification
Molecular formula
C19H27NO3
CAS number
214212-68-3
IUPAC name
5-(1,1-dimethylpentyl)-7-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinoline
State
State

At room temperature, Tetrahydroberberine is in a solid state, typically presenting as a crystalline form or as a powder.

Melting point (Celsius)
160.00
Melting point (Kelvin)
433.00
Boiling point (Celsius)
382.00
Boiling point (Kelvin)
655.00
General information
Molecular weight
301.41g/mol
Molar mass
301.4090g/mol
Density
0.9876g/cm3
Appearence

Tetrahydroberberine typically appears as a crystalline solid or a powder. Its color may vary from white to pale yellow depending on purity and form.

Comment on solubility

Solubility Overview

The compound 5-(1,1-dimethylpentyl)-7-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinoline exhibits unique solubility characteristics owing to its complex molecular structure. Understanding its solubility is crucial for various applications, especially in pharmaceutical formulations and chemical processes.

Key Points on Solubility

  • Polar vs. Nonpolar: This compound's nonpolar characteristics suggest that it may have limited solubility in water but can dissolve well in organic solvents such as ethanol, chloroform, and dichloromethane.
  • Effect of Functional Groups: The presence of the dioxole ring can influence solubility by enhancing the compound's ability to interact with various solubilizing agents, potentially increasing its solubility in mixed solvent systems.
  • Temperature Dependence: Solubility may increase with temperature; thus, controlled heating can be beneficial in dissolving this compound for practical uses.
  • pH Dependency: Although primarily nonpolar, certain ionizable functional groups may exhibit changes in solubility under different pH conditions; however, the specific interplay for this compound requires further investigation.

In conclusion, assessing the solubility of 5-(1,1-dimethylpentyl)-7-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinoline involves considering its interaction with various solvents and conditions. As highlighted, understanding the solubility profile is pivotal for optimizing its application in scientific research and industrial processes.

Interesting facts

Interesting Facts about 5-(1,1-Dimethylpentyl)-7-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinoline

This fascinating compound, often explored in medicinal chemistry, has a structure that combines both isoquinoline and dioxole functionalities, which are interesting in their own right. Here are some intriguing points about this compound:

  • Structural Complexity: The compound contains a tetrahydro isoquinoline structure, which is known for its diverse biological activities. This feature enhances its potential as a therapeutic agent.
  • Biological Activity: Compounds with isoquinoline structures have been shown to exhibit a wide variety of biological activities, including antitumor, anti-inflammatory, and antibacterial properties, making this compound a subject of significant research interest.
  • Pharmacological Potential: Researchers are particularly interested in compounds like this one due to their potential role in drug development. The unique combination of functional groups could lead to novel pharmacological properties.
  • Synthetic Pathways: The synthesis of such a compound can be quite challenging. Chemists often utilize advanced synthetic techniques, including multi-step reactions, to achieve the desired structure efficiently.
  • Impact of Substituents: The presence of the 1,1-dimethylpentyl group can significantly affect the compound's lipophilicity and influence its interaction with biological targets, potentially impacting its pharmacokinetics and efficacy.

As you delve into the world of this compound, remember that its unique structure paves the way for exciting explorations in chemistry and pharmacology. Each element of its design holds clues to its functional behavior and application in medicine.