Skip to main content

Piperine

ADVERTISEMENT
Identification
Molecular formula
C17H19NO3
CAS number
94-62-2
IUPAC name
5-(1,3-benzodioxol-5-yl)-1-(1-piperidyl)penta-2,4-dien-1-one
State
State

At room temperature, piperine is a solid.

Melting point (Celsius)
130.00
Melting point (Kelvin)
403.15
Boiling point (Celsius)
515.00
Boiling point (Kelvin)
788.15
General information
Molecular weight
285.34g/mol
Molar mass
285.3430g/mol
Density
1.1930g/cm3
Appearence

Piperine is a yellow to off-white crystalline solid. It often appears as a powder or irregular crystalline pieces that may clump together. It is known for its slightly spicy, sharp taste, contributing to the characteristic heat of black pepper.

Comment on solubility

Solubility of 5-(1,3-benzodioxol-5-yl)-1-(1-piperidyl)penta-2,4-dien-1-one

The solubility of 5-(1,3-benzodioxol-5-yl)-1-(1-piperidyl)penta-2,4-dien-1-one, with the chemical formula C17H19NO3, can be quite intriguing. Understanding solubility properties is crucial for various applications in pharmaceuticals and organic chemistry. Here are some key points to consider:

  • Solvent Interaction: This compound is likely to display different solubility patterns in polar versus non-polar solvents due to the presence of different functional groups.
  • Polar Solvents: It may exhibit moderate to low solubility in water owing to its sizeable hydrocarbon structure.
  • Non-Polar Solvents: Conversely, enhanced solubility is expected in organic solvents like ethanol or dichloromethane, aligning with its hydrophobic characteristics.
  • Temperature Effects: Increasing temperature typically enhances solubility, so solubility tests at various temperatures could yield insightful results.
  • pH Dependence: The protonation state of the amine group may also influence its solubility profile, particularly in varying pH environments.

In conclusion, investigating the solubility of this compound reveals a complex interplay of its structural attributes and environmental conditions. As highlighted, both the choice of solvent and the condition of the solution can significantly impact its solubility behavior.

Interesting facts

Interesting Facts about 5-(1,3-benzodioxol-5-yl)-1-(1-piperidyl)penta-2,4-dien-1-one

This compound is part of a fascinating class of organic compounds known for their diverse physiological activities and potential therapeutic applications. Here are some interesting facts:

  • Structural Diversity: The presence of both the 1,3-benzodioxole and piperidine moieties in its structure gives it unique chemical properties. These functional groups are commonly found in various natural products and synthetic drugs.
  • Pharmacological Significance: Compounds with similar structures have been studied for their potential in treating a range of conditions, including neurodegenerative disorders and mood-related illnesses. Research indicates that they may interact with neurotransmitter systems in the brain.
  • Research Potential: Given its interesting scaffold, scientists are exploring this compound for its potential use as a ligand in medicinal chemistry and drug discovery, focusing on its ability to modulate biological targets.
  • Environmental Considerations: Many compounds containing the benzodioxole and piperidine units have been highlighted for their eco-compatibility and ability to degrade in the environment, making them interesting candidates in green chemistry initiatives.
  • Analytical Techniques: The study of this compound often involves advanced analytical techniques such as NMR, FTIR, and mass spectrometry to elucidate its structure and confirm its purity, which are essential for any further pharmacological studies.
  • Interdisciplinary Approach: The research and development of this compound often necessitate collaboration between chemists, biologists, and pharmacologists, underscoring the interdisciplinary nature of modern scientific inquiry.

In summary, 5-(1,3-benzodioxol-5-yl)-1-(1-piperidyl)penta-2,4-dien-1-one exemplifies how organic chemistry is linked to valuable applications in medicine and environmental science. As research continues, it holds the promise of unveiling new therapeutic pathways and solutions.

Synonyms
5-(1,3-benzodioxol-5-yl)-1-piperidin-1-ylpenta-2,4-dien-1-one
Piperidine, 1-(5-(1,3-benzodioxol-5-yl)-1-oxo-2,4-pentadienyl)-
1-[5-(1,3-benzodioxol-5-yl)-1-oxo-2,4-pentadienyl]piperidine
2,4-Pentadien-1-one, 5-(1,3-benzodioxol-5-yl)-1-(1-piperidinyl)-, (2E,4E)-
Bioperine;1-Piperoylpiperidine
Spectrum_000323
Prestwick0_000474
Prestwick1_000474
Spectrum2_000049
Spectrum3_000868
Spectrum4_000708
KBioGR_001235
KBioSS_000803
MLS006011979
DivK1c_000954
SPBio_000177
SPBio_002547
CHEMBL3188765
KBio1_000954
KBio2_000803
KBio2_003371
KBio2_005939
KBio3_002015
DTXSID50859166
NINDS_000954
HMS3656M07
SB41065
NCGC00094872-08
SMR001548271
SY048497
NS00076855
5-(3,4-methylenedioxyphenyl)-2,4-pentadienoylpiperidine
(E,E)-1-[5-(1,3-Benzodioxol-5-yl)-1-oxo-2,4-pentadienyl]-piperidine
5-(2H-1,3-benzodioxol-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one