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Benzoylisoquinoline derivative

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Identification
Molecular formula
C20H17NO4
CAS number
208738-92-1
IUPAC name
5-(1,3-benzodioxol-5-ylmethyl)-7-methyl-[1,3]dioxolo[4,5-g]isoquinoline
State
State

The compound is typically a crystalline solid at room temperature.

Melting point (Celsius)
180.00
Melting point (Kelvin)
453.15
Boiling point (Celsius)
460.00
Boiling point (Kelvin)
733.15
General information
Molecular weight
339.34g/mol
Molar mass
339.3440g/mol
Density
1.3400g/cm3
Appearence

This compound appears as a crystalline solid which can vary in color but often is off-white or beige.

Comment on solubility

Solubility of 5-(1,3-benzodioxol-5-ylmethyl)-7-methyl-[1,3]dioxolo[4,5-g]isoquinoline

The solubility of 5-(1,3-benzodioxol-5-ylmethyl)-7-methyl-[1,3]dioxolo[4,5-g]isoquinoline is a topic of significant interest in the field of chemical science. Understanding its solubility behavior can provide insights into its potential applications and interactions with biological systems. Here are a few key points regarding its solubility:

  • Solvent Dependence: The solubility of the compound may vary significantly in different solvents. Organic solvents such as dimethyl sulfoxide (DMSO), methanol, or ethanol might enhance solubility due to their polarity.
  • Temperature Impact: Generally, increasing temperature can increase solubility for many compounds. It is important to investigate the specific thermal properties associated with this compound.
  • Polarity Consideration: Given the presence of aromatic and dioxolane groups, solubility may favor polar environments, thus rendering non-polar solvents less effective.
  • pH Influence: Investigating solubility at different pH levels could be crucial, especially if the compound can ionize under acidic or basic conditions.
  • Crystallization Behaviors: Understanding how the compound crystallizes can help determine practical solubility parameters, as crystalline forms may exhibit different solubility profiles compared to their amorphous counterparts.

In summary, the solubility of 5-(1,3-benzodioxol-5-ylmethyl)-7-methyl-[1,3]dioxolo[4,5-g]isoquinoline is influenced by various factors including solvent type, temperature, polarity, pH, and crystallization behavior. Detailed studies are essential to elucidate its solubility characteristics fully.

Interesting facts

Interesting Facts about 5-(1,3-benzodioxol-5-ylmethyl)-7-methyl-[1,3]dioxolo[4,5-g]isoquinoline

This fascinating compound belongs to a class of organic molecules known for their complex structures and diverse biological activities. Here are some key highlights:

  • Structural Complexity: The compound features a unique polycyclic structure that includes multiple fused rings, contributing to its intriguing chemical properties and potential reactivity.
  • Natural Product Inspiration: This compound's structure is reminiscent of various natural products that exhibit pharmacological activities, making it a compelling subject for medicinal chemistry research.
  • Potential Applications: Compounds with similar structural motifs have been studied for their potential use as anti-cancer agents, anti-inflammatory drugs, and even as neuroprotective agents.
  • Research Interest: Due to its structural attributes, researchers are keen to explore its synthesis, mechanism of action, and interactions with biological targets, which could lead to the development of novel therapeutics.
  • Inspiration from Nature: The incorporation of benzodioxole functionality hints at a lineage from natural products like the well-known psychoactive substances, underscoring the compound's intriguing relationship with the natural world.

As we continue to uncover the intricate relationships between chemical structure and biological activity, 5-(1,3-benzodioxol-5-ylmethyl)-7-methyl-[1,3]dioxolo[4,5-g]isoquinoline stands as a promising candidate for further study, driven by the quest for innovative medicinal compounds. This highlights the beauty of chemistry in bridging the gap between synthetic exploration and the natural world.

Synonyms
Syntaverin
550-73-2
UNII-BQ4UIA304Y
3-Methyl-6,7-methylenedioxy-1-piperonylisoquinoline
BQ4UIA304Y
BRN 0323402
5-(1,3-Benzodioxol-5-ylmethyl)-7-methyl-1,3-dioxolo(4,5-g)isoquinoline
DTXSID30203542
4-27-00-06867 (Beilstein Handbook Reference)
1,3-Dioxolo(4,5-g)isoquinoline, 5-(1,3-benzodioxol-5-ylmethyl)-7-methyl-
1,3-Dioxolo(4,5-g)isoquinoline, 7-methyl-5-piperonyl-
ISOQUINOLINE, 3-METHYL-6,7-METHYLENEDIOXY-1-PIPERONYL-
3-METHYL-6,7-METHYLENEDIOXY-1-PIPERONYLISOQUINOLINE [MI]
DTXCID60126033
Q27274807