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Fluvoxamine

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Identification
Molecular formula
C15H21F3NO3
CAS number
54739-18-3
IUPAC name
5-[2-(4-phenylpiperazin-1-yl)ethyl]oxazolidin-2-one
State
State

Fluvoxamine is typically in a solid state at room temperature. Its crystalline nature allows it to be processed into tablet or capsule form for pharmaceutical use.

Melting point (Celsius)
126.00
Melting point (Kelvin)
399.15
Boiling point (Celsius)
475.15
Boiling point (Kelvin)
748.15
General information
Molecular weight
318.35g/mol
Molar mass
318.3520g/mol
Density
1.3597g/cm3
Appearence

Fluvoxamine appears as an off-white to pale yellow crystalline powder. It is practically insoluble in water, which necessitates careful formulation for pharmaceutical applications.

Comment on solubility

Solubility of 5-[2-(4-phenylpiperazin-1-yl)ethyl]oxazolidin-2-one

The solubility of the compound 5-[2-(4-phenylpiperazin-1-yl)ethyl]oxazolidin-2-one can be influenced by various factors, including its molecular structure and the nature of solvents used. Typically, this compound exhibits:

  • Moderate solubility in polar organic solvents: Compounds featuring an oxazolidinone structure tend to be more soluble in solvents like methanol, ethanol, and dimethyl sulfoxide (DMSO).
  • Limited solubility in non-polar solvents: Its solubility drops significantly in non-polar solvents such as hexane or toluene due to the presence of polar functional groups.
  • pH sensitivity: The solubility might be affected by pH variations, particularly if the compound can exist as a cation or anion depending on the ionic environment.

In conclusion, for practical applications such as drug formulation, it is pivotal to consider the solubility profile thoroughly. As solubility plays a crucial role in bioavailability and efficacy, ensuring compatibility with particular solvents or biological systems is essential. Researchers must perform empirical tests to substantiate the theoretical solubility assumptions.

Interesting facts

Interesting Facts About 5-[2-(4-phenylpiperazin-1-yl)ethyl]oxazolidin-2-one

5-[2-(4-phenylpiperazin-1-yl)ethyl]oxazolidin-2-one is an intriguing chemical compound primarily known for its pharmacological properties. This molecule is notable due to its unique:

  • Structure: The compound features an oxazolidinone ring, which is known for its presence in various biologically active molecules.
  • Functionality: It has demonstrated potential as a therapeutic agent, particularly in the realm of neurological disorders and mental health.
  • Diversity: With the presence of a phenylpiperazine moiety, this compound exhibits interactions with the central nervous system, making it a subject of interest in drug development.

Researchers are particularly captivated by the compound due to:

  1. The potential to influence neurotransmitter systems, such as serotonin and dopamine pathways.
  2. Its resemblance to existing medications, which can aid in modifying current treatments for efficacy and safety.
  3. The ability to serve as a lead compound for synthesizing derivatives that can optimize desired pharmacological effects.

In the field of medicinal chemistry, the exploration of compounds like 5-[2-(4-phenylpiperazin-1-yl)ethyl]oxazolidin-2-one can lead to significant advancements. As noted by researchers in the field, “Connected structural motifs can result in remarkably different biological outcomes.” Understanding the intricate balance between structure and function is key to unraveling new therapeutic avenues.

Overall, this compound stands as a beacon of potential, embodying the creativity and innovation inherent in chemical research.

Synonyms
SCHEMBL9742158