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Furamidine

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Identification
Molecular formula
C8H4N4O4
CAS number
15289-49-3
IUPAC name
5-[2-(5-nitro-2-furyl)vinyl]-3H-1,3,4-oxadiazol-2-one
State
State
Furamidine is typically a solid at room temperature, and it is not very volatile under normal conditions.
Melting point (Celsius)
254.00
Melting point (Kelvin)
527.15
Boiling point (Celsius)
386.00
Boiling point (Kelvin)
659.15
General information
Molecular weight
236.14g/mol
Molar mass
236.1670g/mol
Density
1.6100g/cm3
Appearence

Furamidine is typically a yellow crystalline solid. It may appear as needles or plates and is primarily characterized by its bright yellow color due to the nitrofuryl group.

Comment on solubility

Solubility of 5-[2-(5-nitro-2-furyl)vinyl]-3H-1,3,4-oxadiazol-2-one

The solubility of 5-[2-(5-nitro-2-furyl)vinyl]-3H-1,3,4-oxadiazol-2-one is an intriguing topic, given the unique structure of this compound. With its complex molecular framework, factors influencing its solubility include:

  • Polarity: The presence of functional groups such as the nitro and oxadiazole moiety can impact the overall polarity.
  • Hydrogen bonding: Potential for hydrogen bonding interactions may enhance solubility in polar solvents.
  • Solvent choice: It tends to dissolve more effectively in organic solvents compared to water, making organic solvents like dimethyl sulfoxide (DMSO) a preferable medium.

Data suggests that the compound exhibits limited solubility in water, primarily due to its aromatic structure and the presence of bulky groups, which hinder interactions with water molecules. In general, this compound can be classified as:

  • Low solubility: In polar solvents (e.g., water).
  • Moderate to high solubility: In non-polar solvents (e.g., hexane).

Overall, understanding the solubility of this compound is crucial for its application in various chemical environments. As a final note, solubility plays a critical role in determining the bioavailability and reactivity of this compound in different settings, thus influencing its practical uses in the field of chemistry.

Interesting facts

Interesting Facts about 5-[2-(5-nitro-2-furyl)vinyl]-3H-1,3,4-oxadiazol-2-one

The compound 5-[2-(5-nitro-2-furyl)vinyl]-3H-1,3,4-oxadiazol-2-one is a fascinating compound that showcases the rich chemistry of both heterocycles and nitro compounds. Here are some engaging facts about it:

  • Heterocyclic Chemistry: This compound belongs to the oxadiazole family, which is a well-known class of heterocycles that incorporate nitrogen atoms in their ring structures. Heterocycles play crucial roles in medicinal chemistry, as many pharmaceuticals contain these ring structures.
  • Potential Biological Activity: Compounds like this one, featuring the nitro group, are often explored for their antitumor and antimicrobial properties. The presence of the nitro group can influence the reactivity and mechanism of action in biological systems.
  • Chemical Versatility: The vinyl group suggests potential for further reactions, such as polymerization or cross-coupling, making it an interesting target for synthetic chemists looking to develop new materials.
  • Applications: Researchers are actively investigating compounds with similar structures for applications in the fields of agriculture, where they may serve as pesticides, and in material science, for creating novel polymers.
  • Intriguing Synthesis: The synthetic pathways to create this compound can involve various strategies, including condensation reactions and functional group transformations, highlighting the ingenuity of synthetic organic chemistry.

In studying this compound, one might reflect on the interconnectedness of chemical properties and biological functions, illustrating why compounds like 5-[2-(5-nitro-2-furyl)vinyl]-3H-1,3,4-oxadiazol-2-one remain significant in the realm of chemical research. It exemplifies how even a modest change in structure can lead to profound effects in chemical behavior and potential applications.