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Brotizolam

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Identification
Molecular formula
C15H18BrN2O2
CAS number
57801-81-7
IUPAC name
5-(2-bromoallyl)-5-isopropyl-hexahydropyrimidine-2,4,6-trione
State
State

Brotizolam is generally in a solid state at room temperature.

Melting point (Celsius)
232.00
Melting point (Kelvin)
505.15
Boiling point (Celsius)
400.00
Boiling point (Kelvin)
673.15
General information
Molecular weight
343.17g/mol
Molar mass
343.1720g/mol
Density
1.5200g/cm3
Appearence

Brotizolam typically appears as a white or almost white crystalline powder. It is not often visualized in daily contexts unless processed into medication form.

Comment on solubility

Solubility of 5-(2-bromoallyl)-5-isopropyl-hexahydropyrimidine-2,4,6-trione

The solubility of 5-(2-bromoallyl)-5-isopropyl-hexahydropyrimidine-2,4,6-trione can be influenced by several factors, including its molecular structure and the presence of polar or non-polar functional groups. Understanding its solubility is crucial for various chemical applications and processes.

Key Factors Affecting Solubility:

  • Polar Character: Compounds containing polar functional groups tend to dissolve well in polar solvents, such as water.
  • Hydrophobic Regions: The presence of hydrophobic (non-polar) regions can impair solubility in polar solvents.
  • Temperature: Generally, increasing the temperature of the solvent can increase solubility, especially for solid compounds.
  • pH Levels: For compounds sensitive to acidic or basic conditions, changes in pH can significantly affect solubility.

In the case of 5-(2-bromoallyl)-5-isopropyl-hexahydropyrimidine-2,4,6-trione, the presence of multiple carbon chains and aromatic systems may suggest limited solubility in water but potential solubility in organic solvents like ethanol or methanol. As noted, "the balance between polarity and hydrophobicity plays a pivotal role in the solubility behavior of organic molecules."

This compound's solubility profile could be crucial for experimental procedures or applications in pharmaceuticals and material science. Understanding its solubility will allow chemists to predict its behavior in different environments effectively.

Interesting facts

Interesting Facts About 5-(2-Bromoallyl)-5-Isopropyl-Hexahydropyrimidine-2,4,6-Trione

5-(2-Bromoallyl)-5-isopropyl-hexahydropyrimidine-2,4,6-trione is a fascinating compound with a complex structure and various interesting characteristics. Here are some notable facts:

  • Structural Complexity: This compound is a hexahydropyrimidine derivative, featuring multiple substituents that enrich its chemical behavior and reactivity. The presence of a bromoalkene group introduces opportunities for diverse chemical reactions, including nucleophilic substitution and elimination reactions.
  • Biological Relevance: Compounds of this class have shown intriguing biological activities. They may act as enzyme inhibitors or have potential applications in medicinal chemistry, contributing to the development of new pharmaceuticals.
  • Versatile Synthetic Routes: The synthesis of this compound is intriguing, as it may involve the use of bromoallyl derivatives, enabling chemists to explore various synthetic strategies that can yield different isomers and analogs.
  • Research Potential: With ongoing research in supramolecular chemistry and organic synthesis, compounds like this may hold the key to discovering new materials or catalysts that could revolutionize industrial processes.
  • Analogous Compounds: It belongs to a larger family of pyrimidine derivatives, which are known for their role in nucleic acids and as pharmaceuticals. This connection opens up avenues for exploring their functionality and applications in molecular biology.

As scientists continue to investigate the properties and possibilities of 5-(2-bromoallyl)-5-isopropyl-hexahydropyrimidine-2,4,6-trione, it stands at the intersection of organic synthesis, medicinal chemistry, and biological activity, making it an intriguing subject for further study.

Synonyms
Propallylonal
Propaldon
Ibomal
Bromoaprobarbital
Quietal
Noctal
Noctenal
Quietalum
Kwietal
Nostral
545-93-7
5-(2-Bromoallyl)-5-isopropylbarbituric acid
5-Isopropyl-5-bromallylbarbituric acid
5-Isopropyl-5-(2-bromoallyl)barbituate
BARBITURIC ACID, 5-(2-BROMOALLYL)-5-ISOPROPYL-
2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-(2-bromo-2-propenyl)-5-(1-methylethyl)-
5-(2'-Bromallyl)-5-isopropylbarbituric acid
1ER3Z9GUQH
5-(2-bromoprop-2-enyl)-5-propan-2-yl-1,3-diazinane-2,4,6-trione
5-(2-Bromo-2-propenyl)-5-(1-methylethyl)-2,4,6(1H,3H,5H)-pyrimidinetrione
5-Isopropyl-5-bromoallylbarbituric acid
5-Isopropyl-5-(2-bromoallyl)barbiturate
Ibomalum
5-(.beta.-Bromoallyl)-5-isopropylbarbituric acid
Isopropyl-bromallyl-barbitursaeure
EINECS 208-896-7
UNII-1ER3Z9GUQH
BRN 0219943
PROPALLYLONAL [MI]
4-24-00-01994 (Beilstein Handbook Reference)
SCHEMBL713682
PROPALLYLONAL [WHO-DD]
DTXSID00202906
CHEBI:135199
KTGWBBOJAGDSHN-UHFFFAOYSA-N
STL481976
AKOS003398682
NS00003752
5-Isopropyl-5-(2-bromoallyl)-barbituric acid
propallylonal, noctal, nostal, quietal, ibomal
Q7250078
5-(2-Bromo-2-propenyl)-5-isopropyl-2,4,6(1H,3H,5H)-pyrimidinetrione #
5-(2-bromoprop-2-en-1-yl)-5-isopropylpyrimidine-2,4,6(1H,3H,5H)-trione
pyrimidine-2,4,6(1H,3H,5H)-trione, 5-(2-bromoallyl)-5-isopropyl-
5-(2-BROMO-2-PROPEN-1-YL)-5-(1-METHYLETHYL)-2,4,6(1H,3H,5H)-PYRIMIDINETRIONE
5-(2-bromoprop-2-en-1-yl)-5-(propan-2-yl)pyrimidine-2,4,6(1H,3H,5H)-trione
2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-(2-bromo-2-propen-1-yl)-5-(1-methylethyl)-2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-(2-bromo-2-propenyl)-5-(1-methylethyl)- (9CI); Barbituric acid, 5-(2-bromoallyl)-5-isopropyl- (8CI); 5-(2-Bromoallyl)-5-isopropylbarbituric a