5-[(2-chlorophenyl)methylene]-3-(p-tolyl)-2-sulfanyl-imidazol-4-one

Identification

Molecular formula

C₁₇H₁₃ClN₂OS

CAS number

141676-07-9

IUPAC name

5-[(2-chlorophenyl)methylene]-3-(p-tolyl)-2-sulfanyl-imidazol-4-one

State

At room temperature, this compound is in a solid state, typically forming a crystalline powder.

Melting point (Celsius)

195.00

Melting point (Kelvin)

468.15

Boiling point (Celsius)

502.00

Boiling point (Kelvin)

775.15

General information

Molecular weight

361.81g/mol

Molar mass

361.8500g/mol

Density

1.3000g/cm³

Appearence

The compound 5-[(2-chlorophenyl)methylene]-3-(p-tolyl)-2-sulfanyl-imidazol-4-one typically appears as a crystalline solid. Its exact color and form can vary, but it is often encountered as a pale yellow to off-white powder.

Comment on solubility

Solubility Characteristics

The compound 5-[(2-chlorophenyl)methylene]-3-(p-tolyl)-2-sulfanyl-imidazol-4-one is a complex organic molecule that poses unique solubility challenges.

Key factors influencing the solubility of this compound include:

Polarity: The presence of the nitrogen and sulfur atoms in the imidazole ring suggests potential polar interactions, which can enhance solubility in polar solvents.
Substituents: The bulky p-tolyl and 2-chlorophenyl groups may impede solubility in aqueous solutions due to steric hindrance, leading to increased hydrophobic character.
Hydrogen Bonding: The compound may engage in hydrogen bonding, especially with protic solvents, affecting its solubility favorably in specific organic solvents.

Overall, while the polar character derived from the imidazole and the possible hydrogen bonding interactions suggest that the compound might have better solubility in polar organic solvents, the considerable hydrophobic groups could limit solubility in water. As such, it is likely to exhibit:

Good solubility in dimethyl sulfoxide (DMSO)
Moderate solubility in ethanol and methanol
Poor solubility in water

In conclusion, the solubility profile of 5-[(2-chlorophenyl)methylene]-3-(p-tolyl)-2-sulfanyl-imidazol-4-one is influenced by a balance of polar and non-polar characteristics, making it essential to consider solvent choice carefully for practical applications.

Interesting facts

Interesting Facts about 5-[(2-chlorophenyl)methylene]-3-(p-tolyl)-2-sulfanyl-imidazol-4-one

This fascinating compound possesses several intriguing features that highlight its importance in the field of chemistry and potential applications:

Versatile Structure: The compound exhibits a unique imidazole core, a common motif in various biological molecules, which is known for its involvement in crucial physiological processes.
Biological Relevance: Compounds containing the imidazole ring are frequently studied for their biological activities, including antimicrobial and antifungal properties. This particular compound has garnered interest in pharmaceutical research.
Halogen Substituent Effects: The presence of the chlorine atom on the phenyl ring can significantly influence the reactivity and biological activity of the compound. Halogens often enhance lipophilicity, impacting the absorption and distribution of drugs.
Sulfanyl Group Influence: The sulfanyl (thioether) moiety is notable for imparting distinctive chemical properties. Sulfur-containing compounds often exhibit improved bioactivity, making them valuable in drug design.
Potential Applications: This compound could serve as a lead structure for the development of new therapeutic agents. Its unique arrangement of functional groups may pave the way for novel treatments in various medical fields.

As scientists delve into the complexities of such compounds, it becomes increasingly clear that in the world of organic chemistry, intricate structures often lead to fascinating discoveries.