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Medazepam

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Identification
Molecular formula
C16H15ClN2O
CAS number
2898-12-6
IUPAC name
5-[2-(diethylamino)ethyl]-11H-benzo[b][1,4]benzodiazepin-6-one
State
State

Medazepam is in a solid state at room temperature.

Melting point (Celsius)
134.00
Melting point (Kelvin)
407.15
Boiling point (Celsius)
425.00
Boiling point (Kelvin)
698.15
General information
Molecular weight
355.45g/mol
Molar mass
355.4510g/mol
Density
1.1620g/cm3
Appearence

Medazepam is typically found in its solid form as a white to yellowish crystalline powder.

Comment on solubility

Solubility of 5-[2-(diethylamino)ethyl]-11H-benzo[b][1,4]benzodiazepin-6-one

The solubility of 5-[2-(diethylamino)ethyl]-11H-benzo[b][1,4]benzodiazepin-6-one in various solvents can be quite intricate due to its structural characteristics. Generally, the solubility is influenced by:

  • Polarity: This compound possesses a significant degree of polarity, primarily due to the presence of the diethylamino group. This characteristic often enhances solubility in polar solvents.
  • Solvent Type: The compound is expected to be soluble in organic solvents such as ethanol, methanol, and dimethyl sulfoxide (DMSO), while its solubility in water may be limited.
  • Functional Groups: The existence of multiple functional groups can lead to hydrogen bonding, which can either enhance or limit solubility based on the solvent.

In practical applications, it is crucial to consider factors like temperature and pH, as these can greatly influence solubility. For instance, as temperature increases, solubility may also increase for many organic compounds.

In summary, while 5-[2-(diethylamino)ethyl]-11H-benzo[b][1,4]benzodiazepin-6-one exhibits notable solubility characteristics, it is essential to evaluate the specific conditions and solvents to determine its effective solubility.

Interesting facts

Interesting Facts about 5-[2-(diethylamino)ethyl]-11H-benzo[b][1,4]benzodiazepin-6-one

The compound 5-[2-(diethylamino)ethyl]-11H-benzo[b][1,4]benzodiazepin-6-one is part of the benzodiazepine family, which is renowned for its psychological and pharmacological significance. This chemical structure showcases a unique combination of elements that contribute to its biological activity, making it a subject of extensive research.

Key Characteristics

  • Neuropharmacological Potential: This compound exhibits properties that can modulate the central nervous system, often leading to anxiolytic, sedative, and muscle relaxant effects.
  • Structure-Activity Relationship: Its structure allows for various substitutions that can significantly alter potency, efficacy, and side effects, making each derivative unique.
  • Medicinal Use: Compounds in the benzodiazepine class have been extensively used in clinical settings to treat conditions such as anxiety disorders, insomnia, and seizures.

Research Insights

Studies have demonstrated that the diethylamino group significantly influences the drug's lipophilicity and receptor binding affinity, resulting in enhanced pharmacological profiles.

As noted by researchers, "Compounds like 5-[2-(diethylamino)ethyl]-11H-benzo[b][1,4]benzodiazepin-6-one highlight the intricate dance between chemical structure and biological effect." This emphasizes the importance of synthetic chemistry in designing effective therapeutic agents.

Future Directions

With ongoing research into its effects and potential, there is a promising future for compounds such as this in the realm of psychiatric medicine. New developments could pave the way for safer and more effective treatments for mental health conditions.

The continued exploration of compounds like this one reveals the vast potential that lies in the world of chemistry, offering hope for innovative treatments and enhancing our understanding of complex biochemical processes.

Synonyms
BRN 0692247
4343-43-5
11H-DIBENZO(b,e)(1,4)DIAZEPIN-11-ONE, 5,10-DIHYDRO-10-(2-(DIETHYLAMINO)ETHYL)-
DTXSID40195848
10-(2-(Diethylamino)ethyl)-5,10-dihydro-11H-dibenzo(b,e)(1,4)diazepin-11-one
DTXCID80118339
5-24-04-00111 (beilstein handbook reference)