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Clonazepam

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Identification
Molecular formula
C16H13ClN2O
CAS number
1622-61-3
IUPAC name
5-[2-(dimethylamino)ethyl]-3,11-dimethyl-benzo[b][1,4]benzodiazepin-6-one
State
State

At room temperature, clonazepam exists as a solid compound. It is stable under standard conditions but should be stored in a cool, dry place to prevent decomposition or loss of effectiveness, which can occur due to exposure to environmental factors such as moisture or high temperatures.

Melting point (Celsius)
237.00
Melting point (Kelvin)
510.15
Boiling point (Celsius)
363.50
Boiling point (Kelvin)
636.70
General information
Molecular weight
315.72g/mol
Molar mass
353.7740g/mol
Density
1.4000g/cm3
Appearence

Clonazepam typically appears as a white or light yellow crystalline powder. It is a light-sensitive compound that should be stored in an environment protected from light to maintain its stability and effectiveness. It is not soluble in water but is soluble in alcohol or acetone, which is used in its formulation for medical purposes.

Comment on solubility

Solubility of 5-[2-(dimethylamino)ethyl]-3,11-dimethyl-benzo[b][1,4]benzodiazepin-6-one

The solubility of 5-[2-(dimethylamino)ethyl]-3,11-dimethyl-benzo[b][1,4]benzodiazepin-6-one, a complex organic compound, is influenced by various factors. Here are some key points to consider:

  • Polar vs. Non-Polar Characteristics: Due to its disposition of polar and non-polar segments, the solubility tends to be better in organic solvents such as ethanol or dimethyl sulfoxide (DMSO) rather than in water.
  • Functional Groups: The presence of the dimethylamino group enhances interactions with solvents capable of hydrogen bonding, which may increase solubility in certain environments.
  • Temperature Dependence: Solubility often increases with temperature; thus, elevated temperatures may help dissolve this benzodiazepine derivative more efficiently in suitable solvents.

In general, it is vital to conduct empirical studies to determine precise solubility data, as theoretical predictions may not always capture the compound's behavior accurately. As the compound's structure is intricate, its behavior in various environments might yield interesting results, echoing the complexity of its molecular architecture.

Ultimately, the solubility profile of this compound can be summarized by the quote: “Like dissolves like,” reinforcing the importance of matching polarities when selecting solvents for dissolution.

Interesting facts

Interesting Facts about 5-[2-(Dimethylamino)ethyl]-3,11-dimethyl-benzo[b][1,4]benzodiazepin-6-one

This compound is a fascinating member of the benzodiazepine family, known for its diverse pharmacological properties. Benzodiazepines are primarily recognized for their sedative, anxiolytic, and muscle-relaxant effects, making them important in the field of medicine.

Key Characteristics

  • Structural Complexity: This compound features a unique structure that includes a dimethylaminoethyl group, contributing to its distinct chemical behavior and potential effects.
  • Pharmacological Importance: Compounds like this are often studied for their potential in treating anxiety, insomnia, and other related disorders.
  • Research Applications: Due to its complex nature, it may be used in various research settings to explore new therapeutic approaches or to develop novel medicines.

Noteworthy Aspects

One of the intriguing aspects of this compound is its ability to interact with the central nervous system. Benzodiazepines work by enhancing the effect of the neurotransmitter gamma-aminobutyric acid (GABA), leading to increased sedation and decreased anxiety. As a scientist, observing the interactions this compound has on synaptic activity can unveil pathways for treating neurological conditions.

Interestingly, synthetic modifications, such as those found in this compound, can lead to variations in efficacy and side effect profiles, which are crucial for medicinal chemistry research. The ability to fine-tune such compounds highlights the art and science of drug discovery.

Overall, the exploration of 5-[2-(dimethylamino)ethyl]-3,11-dimethyl-benzo[b][1,4]benzodiazepin-6-one not only opens doors to understanding better therapeutics but also illustrates the intricate balance of chemistry and biology in developing effective treatments.