Interesting facts
Interesting Facts about 5-(2-fluorophenyl)-1-methyl-7-nitro-3H-1,4-benzodiazepin-2-one
The compound known as 5-(2-fluorophenyl)-1-methyl-7-nitro-3H-1,4-benzodiazepin-2-one is an intriguing member of the benzodiazepine family, which is well-regarded for its pharmacological significance. Here are some compelling aspects of this compound:
- Pharmacological Role: This compound exhibits potential activity as a central nervous system depressant, similar to other benzodiazepines. It plays a crucial role in the management of anxiety and seizure disorders.
- Research Implications: The presence of a fluorine atom, specifically in the 2-position of the phenyl ring, can impact the compound's biological properties, enhancing its potency and selectivity.
- Synthetic Pathways: The synthesis of this compound can involve multi-step organic reactions, providing a fascinating study of chemical transformations and reaction mechanisms.
- Chemical Structure: The unique structure of this molecule, characterized by its nitro group, offers diverse interaction capabilities with biological targets, making it a point of interest for medicinal chemists.
- Potential Applications: Beyond its anticipated medicinal uses, compounds like this are often leveraged in drug design to develop new therapies for neuropsychiatric disorders.
- Complementary Research: Ongoing studies may involve structural modification of the compound to enhance desired therapeutic effects while reducing side effects.
In conclusion, the exploration of 5-(2-fluorophenyl)-1-methyl-7-nitro-3H-1,4-benzodiazepin-2-one not only deepens our understanding of benzodiazepines but also prompts new inquiries into how slight modifications can lead to substantial changes in a compound's efficacy and safety profile. As Nobel laureate Richard Feynman aptly stated, "What I cannot create, I do not understand," reminding us of the potent interplay between chemistry and biology in drug development.
Synonyms
flunitrazepam
Rohypnol
1622-62-4
Narcozep
Roipnol
Fluninoc
Primun
flunipam
Flunitrazepamum
Fluridrazepam
Flunitrazepamum [INN-Latin]
Silece
Ro 5-4200
flunidazepam
RO-5-4200
[3H]flunitrazepam
Rohypnol (TN)
Flunitrazepam [USAN:INN:BAN:JAN]
2H-1,4-Benzodiazepin-2-one, 5-(2-fluorophenyl)-1,3-dihydro-1-methyl-7-nitro-
5-(o-Fluorophenyl)-1,3-dihydro-1-methyl-7-nitro-2H-1,4-benzodiazepin-2-one
Hipnosedon
CCRIS 5287
Flunita
Fluscand
Hypnodorm
Valsera
5-(2-fluorophenyl)-1-methyl-7-nitro-3H-1,4-benzodiazepin-2-one
Hypnor
Primum
RO54200
HSDB 6960
EINECS 216-597-8
Ro-54200
1-Methyl-7-nitro-5-(2-fluorophenyl)-3H-1,4-benzodiazepin-2(1H)-one
1,3-Dihydro-5-(o-fluorophenyl)-1-methyl-7-nitro-2H-1,4-benzodiazepin-2-one
BRN 0702691
DEA No. 2763
UNII-620X0222FQ
N05CD03
FLUNITRAZEPAM [MI]
620X0222FQ
FLUNITRAZEPAM [INN]
FLUNITRAZEPAM [JAN]
FLUNITRAZEPAM [HSDB]
FLUNITRAZEPAM [USAN]
CHEMBL13280
FLUNITRAZEPAM [MART.]
2H-1,4-BENZODIAZEPIN-2-ONE, 1,3-DIHYDRO-5-(2-FLUOROPHENYL)-1-METHYL-7-NITRO-
FLUNITRAZEPAM [WHO-DD]
DTXSID7023065
CHEBI:31622
5-24-04-00350 (Beilstein Handbook Reference)
FLUNITRAZEPAM [EP MONOGRAPH]
5-(2-Fluorophenyl)-1-methyl-7-nitro-1,3-dihydro-2H-1,4-benzodiazepin-2-one
5-(2-fluorophenyl)-1-methyl-7-nitro-2,3-dihydro-1H-1,4-benzodiazepin-2-one
Flunitrazepamum (INN-Latin)
FLUNITRAZEPAM (MART.)
Flunitrazepan
FLUNITRAZEPAM (EP MONOGRAPH)
5-(2-Fluorophenyl)-1-methyl-7-nitro-1,3-dihydrobenzo[e][1,4]diazepin-2-one
Flunitrazepam (1.0 mg/mL in Methanol)
Flunitrazepam (1.0mg/ml in Acetonitrile)
Roofies
5-(2-Fluorophenyl)-1-methyl-7-nitro-1,3-dihydrobenzo(e)(1,4)diazepin-2-one
[3H]Rohypnol
Flunitrazepamum (Latin)
5-(2-Fluorophenyl)-1-methyl-7-nitro-1H-benzo[e][1,4]diazepin-2(3H)-one
SCHEMBL44169
MLS003899224
DivK1c_000981
DTXCID103065
GTPL4193
GTPL4360
BDBM25878
HMS503E03
KBio1_000981
NINDS_000981
Flunitrazepam (JP17/USAN/INN)
Flunitrazepam, 1mg/ml in Methanol
LBC44808
UIA53364
NSC708829
Flunitrazepam 0.1 mg/ml in Methanol
Flunitrazepam 1.0 mg/ml in Methanol
AKOS005066009
DB01544
NSC-708829
IDI1_000981
SMR000058981
DB-043520
NS00007996
D01230
Q62947
A810363
Flunitrazepam, European Pharmacopoeia (EP) Reference Standard
Flunitrazepam-13C6, 100 mug/mL in methanol, certified reference material
(E)-5-(2-fluorophenyl)-1-methyl-7-nitro-1H-benzo[e][1,4]diazepin-2(3H)-one
1,3-dihydro-5-(2-fluorophenyl)-1-methyl-7-nitro-2H-1,4-benzodiazepin-2-one
5-(2-Fluorophenyl)-1-methyl-7-nitro-1,3-dihydro-2H-1,4-benzodiazepin-2-one #
216-597-8
Circles, Forget Me Pill, La Rocha, Lunch Money Drug, Mexican Valium, Pingus, R2, Roach 2, Ruffies, Rophies, Wolfies
Solubility of 5-(2-fluorophenyl)-1-methyl-7-nitro-3H-1,4-benzodiazepin-2-one
The solubility of 5-(2-fluorophenyl)-1-methyl-7-nitro-3H-1,4-benzodiazepin-2-one (C16H12FN3O3) can be considered through the following aspects:
Therefore, understanding the solubility characteristics of this compound is crucial for its applications in various chemical and pharmaceutical contexts, especially in formulations where optimal bioavailability is required. As a general remark, “The solubility of a compound is key to unlocking its potential in biomolecular interactions.”