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Identification
Molecular formula
C15H21N4
CAS number
not available
IUPAC name
5-[(2-methylpyridin-1-ium-1-yl)methyl]-2-propyl-pyrimidin-4-amine
State
State

This compound is typically a solid at room temperature. It is often handled in powder form, allowing ease of use in varied chemical processes or for analytical study.

Melting point (Celsius)
152.50
Melting point (Kelvin)
425.65
Boiling point (Celsius)
315.00
Boiling point (Kelvin)
588.15
General information
Molecular weight
256.32g/mol
Molar mass
256.3240g/mol
Density
1.2300g/cm3
Appearence

The compound appears as a crystalline solid. It is characterized by a whitish or pale yellow color depending on its purity and form. The solid is often finely divided and may form slightly more yellowish hue when impure or older due to potential oxidation or contamination.

Comment on solubility

Solubility of 5-[(2-methylpyridin-1-ium-1-yl)methyl]-2-propyl-pyrimidin-4-amine

The solubility of 5-[(2-methylpyridin-1-ium-1-yl)methyl]-2-propyl-pyrimidin-4-amine, with the chemical formula C15H21N4, presents an intriguing consideration due to its unique structural characteristics. Understanding its solubility can aid in predicting its behavior in various chemical environments.

Factors affecting the solubility of this compound include:

  • Polarity: The presence of polar regions due to the amino and pyridinic groups suggests that this compound may exhibit moderate solubility in polar solvents such as water.
  • Hydrogen bonding: The amine functional group can participate in hydrogen bonding, enhancing solubility in polar environments.
  • Alkyl groups: The propyl chain contributes hydrophobic characteristics, which may decrease solubility in aqueous solutions.

As a result, one might expect the compound to be:

  • Soluble in: Polar solvents (e.g., water, alcohols)
  • Partially soluble in: Organic solvents that have moderate polarity
  • Insoluble in: Non-polar solvents

In summary, while the solubility of 5-[(2-methylpyridin-1-ium-1-yl)methyl]-2-propyl-pyrimidin-4-amine in specific solvents may vary, it can generally be anticipated to possess enhanced solubility in polar media due to its structural functionality. This balance between hydrophobic and hydrophilic characteristics allows for a diverse range of applications within chemical processes.

Interesting facts

Interesting Facts About 5-[(2-methylpyridin-1-ium-1-yl)methyl]-2-propyl-pyrimidin-4-amine

This compound belongs to a fascinating class known as pyrimidines, which are aromatic rings featuring nitrogen atoms in their structure. Here are some intriguing aspects of this compound:

  • Diverse Applications: The presence of both pyrimidine and pyridine rings makes this compound relevant in medicinal chemistry. Compounds with similar structures are often explored for their potential as therapeutic agents.
  • Ionizable Moiety: The 2-methylpyridin-1-ium group contributes to the compound's ability to interact with biological molecules, enhancing its potential to function as a drug candidate.
  • Biological Significance: Pyrimidines are key components of nucleic acids such as DNA and RNA. Therefore, compounds derived from or related to pyrimidines are crucial in studies of genetics and biochemistry.

As a student or researcher, it’s exciting to consider how modifying certain substituents on the pyrimidine or pyridine rings can lead to vastly different biological activities. This showcases the power of structural chemistry in drug development. As the famous chemist Linus Pauling once said, "The best way to have a good idea is to have a lot of ideas." This is particularly relevant in organic synthesis, where creativity and variations lead to novel compounds with desirable properties.

Furthermore, understanding the synthesis pathways and reactivity of such compounds allows chemists to tailor them effectively for specific roles in various applications, from pharmaceuticals to agricultural chemistry.

Synonyms
amprolium
Amprolium ion
13082-85-4
UNII-H2T307KMZR
H2T307KMZR
5-[(2-methylpyridin-1-ium-1-yl)methyl]-2-propylpyrimidin-4-amine
CHEBI:85266
Picolinium, 1-((4-amino-2-propyl-5-pyrimidinyl)methyl)-2-
Pyridinium, 1-((4-amino-2-propyl-5-pyrimidinyl)methyl)-2-methyl-
A1H5C
CHEMBL97350
DTXSID9048140
1-[(4-amino-2-propylpyrimidin-5-yl)methyl]-2-methylpyridinium
amprolium cation
amprolium(1+)
Spectrum_000052
Prestwick0_000008
Prestwick1_000008
Prestwick2_000008
Prestwick3_000008
Spectrum2_000122
Spectrum3_000302
Spectrum4_000150
Spectrum5_000816
BSPBio_000015
BSPBio_001864
KBioGR_000600
KBioSS_000432
DivK1c_000149
SCHEMBL363586
SPBio_000164
SPBio_001936
1-<(2-Propyl-4-amino-5-pyrimidinyl)methyl>pyridinium
BPBio1_000017
CHEMBL1179735
KBio1_000149
KBio2_000432
KBio2_003000
KBio2_005568
KBio3_001364
NINDS_000149
1-(4-amino-2-propyl-pyrimidin-5-ylmethyl)-2-methyl-pyridinium
5-[(2-methylpyridin-1-ium-1-yl)methyl]-2-propyl-pyrimidin-4-amine
BDBM50027794
STL018669
ZINC00000934
AKOS005657179
IDI1_000149
NCGC00017020-06
SBI-0051284.P003
NS00008141
BRD-K90027121-003-01-7
BRD-K90027121-300-08-2
BRD-K90027121-300-13-2
Q27158445
1-[(4-Amino-2-propyl-5-pyrimidinyl)methyl]-2-methylpyridinium
1-[(4-amino-2-propylpyrimidin-5-yl)methyl]-2-methylpyridin-1-ium
1-(4-Amino-2-propyl-pyrimidin-5-ylmethyl)-2-methyl-pyridinium; chloride
1-(4-Amino-2-propyl-pyrimidin-5-ylmethyl)-2-methyl-pyridinium chloride; Hydrochloride(Amprolium)