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Cilomilast

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Identification
Molecular formula
C14H18N2O2S1
CAS number
153259-65-5
IUPAC name
5-(2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl)pentanamide
State
State
Cilomilast is a solid at room temperature, typically existing in a crystalline powder form.
Melting point (Celsius)
249.00
Melting point (Kelvin)
522.15
Boiling point (Celsius)
338.50
Boiling point (Kelvin)
611.65
General information
Molecular weight
349.43g/mol
Molar mass
349.4300g/mol
Density
1.4500g/cm3
Appearence

Cilomilast typically appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of 5-(2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl)pentanamide

The solubility of the compound C14H18N2O2S1, also known as 5-(2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl)pentanamide, is influenced by its unique chemical structure and functional groups. Several factors contribute to its solubility characteristics:

  • Polar vs. Non-Polar: The presence of polar functional groups such as amides and carbonyls typically enhances solubility in polar solvents like water.
  • Hydrogen Bonding: The ability of the compound to engage in hydrogen bonding can significantly affect its solubility, making it more soluble in solvent systems that can participate in similar interactions.
  • Aliphatic and Aromatic Structures: Aliphatic chains tend to be more soluble in non-polar solvents, while aromatic sections can influence the solubility profile in various solvents.

In general, one can expect this compound to have variable solubility characteristics but lean towards being soluble in polar solvents owing to its amide and carbonyl functionalities. However, exact solubility data should be obtained experimentally for practical applications. As the adage goes, "like dissolves like." Therefore, understanding the solubility behavior of such a compound is essential for its utilization in various chemical applications.

Interesting facts

Interesting Facts about 5-(2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl)pentanamide

This intriguing compound, 5-(2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl)pentanamide, is a notable member of the imidazole family, showcasing a blend of complex ring structures and functional amide groups. Here are some highlights regarding its properties and significance:

  • Pharmaceutical Potential: Many compounds containing imidazole rings have been studied for their pharmaceutical applications. They often exhibit biological activity and may play key roles in drug discovery, particularly for conditions like cancer and infections.
  • Unique Structure: The thieno[3,4-d]imidazole core is quite distinctive, featuring a fused ring system that could result in interesting electronic properties and interactions, making it a subject of interest in materials science.
  • Research Applications: Compounds related to this structure can be used to explore therapeutic avenues for various diseases, potentially acting as enzyme inhibitors or receptor modulators.
  • Synthetic Challenges: The synthesis of such complex organic molecules with multiple reactive centers provides fascinating challenges for chemists, exemplifying the importance of creativity and precision in modern organic synthesis.
  • Chemical Versatility: Its functional groups, including the amide moiety, offer reactive sites, allowing for further derivatization and functionalization. This versatility can be leveraged for designing more active pharmacophores.

As you delve into the world of organic chemistry, this compound stands as a testament to the intricate nature of molecular design and the myriad ways in which scientists can harness them for human benefit. It epitomizes the blend of structure and function that is central to effective medicinal chemistry.

In summary, the potential applications and exciting structural features of 5-(2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl)pentanamide make it a valuable target for ongoing research within the scientific community. The complex architecture hints at rich avenues for exploration, inviting chemists to unlock its secrets.

Synonyms
5-(2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide
SCHEMBL8932330
DTXSID10863961
5-(2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl)pentanamide
Z899154084