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Berberine

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Identification
Molecular formula
C20H18NO4
CAS number
2086-83-1
IUPAC name
5-(2,2-dimethylpropyl)-7-methyl-[1,3]dioxolo[4,5-g]isoquinoline
State
State

At room temperature, berberine is typically in a solid state, forming fine yellow crystalline powder.

Melting point (Celsius)
145.00
Melting point (Kelvin)
418.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
336.36g/mol
Molar mass
335.3650g/mol
Density
1.3600g/cm3
Appearence

Berberine typically appears as a yellow crystalline powder. It is often used as an indicator dye owing to its vibrant yellow color. Under microscopic observation, it forms needle-like crystals.

Comment on solubility

Solubility of 5-(2,2-dimethylpropyl)-7-methyl-[1,3]dioxolo[4,5-g]isoquinoline

The solubility of 5-(2,2-dimethylpropyl)-7-methyl-[1,3]dioxolo[4,5-g]isoquinoline in various solvents can offer valuable insights into its potential applications and utility in chemical processes. This compound, characterized by its unique structure, exhibits the following solubility traits:

  • Polar Solvents: Generally, compounds with an isoquinoline structure tend to show moderate solubility in polar solvents such as ethanol and methanol.
  • Non-Polar Solvents: The presence of bulky aliphatic groups, like 2,2-dimethylpropyl, may enhance its solubility in non-polar solvents, such as hexane or toluene.
  • Aqueous Solubility: Due to its complex structure, this compound may exhibit low aqueous solubility, making it less favorable for applications in strictly aqueous environments.

It is important to note that the actual solubility can significantly vary based on factors such as temperature, pH, and the presence of other chemical species. As a reminder, in the words of chemist Linus Pauling, "The properties of a substance are determined by structure." Thus, understanding the solubility behavior is critical for the effective utilization of this compound in various chemical reactions and formulations.

Interesting facts

Exploring 5-(2,2-dimethylpropyl)-7-methyl-[1,3]dioxolo[4,5-g]isoquinoline

5-(2,2-dimethylpropyl)-7-methyl-[1,3]dioxolo[4,5-g]isoquinoline is a fascinating compound that offers intriguing insights into the world of organic chemistry. Known for its complex structure, this compound is part of a larger family of isoquinoline derivatives, which play significant roles in medicinal chemistry and pharmacology.

Key Features and Applications

  • Structure: The unique arrangement of dioxole and isoquinoline moieties contributes to its distinctive chemical properties.
  • Biological Relevance: Isoquinoline derivatives are often explored for their potential as pharmacologically active agents, indicating that this compound may possess interesting biological activities.
  • Synthetic Chemistry: The synthesis of such compounds can be quite challenging, often requiring advanced techniques in organic synthesis, making it a valuable topic for research and study.

Its significant structure allows for a variety of functionalizations, making it a subject of interest for organic chemists. As a versatile compound, it can potentially lead to new discoveries in drug development, especially in areas targeting neurological and cardiovascular diseases.

Research Insights

Researchers are particularly interested in compounds like 5-(2,2-dimethylpropyl)-7-methyl-[1,3]dioxolo[4,5-g]isoquinoline due to their:

  1. Potential to serve as precursors in the synthesis of more complex molecules.
  2. Ability to interact with biological systems in unique ways, which could pave the way for novel therapeutic agents.
  3. Role in studying structure-activity relationships (SAR) that help in understanding how variations in chemical structures can affect biological effects.

In conclusion, 5-(2,2-dimethylpropyl)-7-methyl-[1,3]dioxolo[4,5-g]isoquinoline is more than just a compound—it's a gateway to understanding intricate chemical interactions and developing potential new medicines. Its complex structure and potential applications make it an exciting area of study for both chemistry students and seasoned researchers alike.