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Dapoxetine

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Identification
Molecular formula
C21H23N3O4
CAS number
119356-77-3
IUPAC name
5-[3-[2,6-dimethyl-4-(2-methyltetrazol-5-yl)phenoxy]propyl]-3-methyl-isoxazole
State
State

At room temperature, Dapoxetine is a solid.

Melting point (Celsius)
175.00
Melting point (Kelvin)
448.15
Boiling point (Celsius)
577.90
Boiling point (Kelvin)
851.05
General information
Molecular weight
341.43g/mol
Molar mass
341.8790g/mol
Density
1.2508g/cm3
Appearence

Dapoxetine is a white to off-white crystalline powder.

Comment on solubility

Solubility of 5-[3-[2,6-dimethyl-4-(2-methyltetrazol-5-yl)phenoxy]propyl]-3-methyl-isoxazole

The solubility of a compound plays a crucial role in its application and effectiveness, especially in pharmaceutical and chemical contexts. For the compound 5-[3-[2,6-dimethyl-4-(2-methyltetrazol-5-yl)phenoxy]propyl]-3-methyl-isoxazole (C21H23N3O4), understanding its solubility characteristics can provide insight into its potential uses. Here are some key considerations:

  • Polarity: The presence of multiple functional groups suggests that the molecule could exhibit a range of polar and non-polar characteristics, potentially influencing solubility in various solvents.
  • Solvent Compatibility: Compounds with intricate structures, such as this one, may have better solubility in polar solvents like water or alcohols, but may also dissolve in organic solvents due to hydrophobic regions.
  • Concentration Effects: As with many compounds, solubility can vary significantly with changes in concentration, temperature, and pH, making it essential to consider these factors during practical applications.
  • Crystallinity: The physical form of the compound—whether it is crystalline or amorphous—may also impact its solubility; amorphous forms tend to be more soluble.

As such, understanding the solubility of this compound is vital for its effective use in formulations. Careful experimentation can help determine the best conditions for its solubility, optimizing its performance in various applications.

Interesting facts

Interesting Facts about 5-[3-[2,6-Dimethyl-4-(2-methyltetrazol-5-yl)phenoxy]propyl]-3-methyl-isoxazole

This compound represents a fascinating exploration into the world of organic chemistry and drug development. As a member of the isoxazole family, it plays a significant role in medicinal chemistry due to its unique structure and functional properties. Here are some intriguing aspects:

  • Complex Structure: The compound features a triad of functional groups, contributing to its biological activity. The isoxazole ring, together with a phenolic component and a side chain, creates potential for diverse interactions with biological targets.
  • Biological Activity: Compounds with similar structures are often investigated for anti-inflammatory and analgesic properties. Their ability to interact with different biological pathways opens avenues for drug development.
  • Drug Design: The incorporation of dimethyl and tetrazole groups showcases the significance of substituents in modulating bioactivity. The presence of such groups can enhance solubility and selectivity for specific biological targets.
  • Research Applications: Scientists have shown interest in this compound as a potential lead in the development of therapies. Its unique combination of properties makes it a candidate for a variety of pharmacological studies.
  • Synthetic Challenges: The synthesis of this compound might present challenges, particularly in maintaining the integrity of sensitive functional groups during reaction processes. This invites innovative synthetic approaches and methodologies.

As one delves into the nuances of this compound, it not only serves as a valuable tool in the realm of medicinal chemistry, but also highlights the importance of molecular design in developing effective therapies. The art of crafting such molecules continues to be a multidimensional puzzle that chemists passionately engage with, affirming the significance of creativity and science working hand-in-hand.

Synonyms
2,6-dimethyl-1-(3-[3-methyl-5-isoxazolyl]-propanyl)-4-[2n-methyl-2h-tetrazol-5-yl]-phenol
2,6-Dimethyl-1-(3-(3-methyl-5-isoxazolyl)-propanyl)-4-(2N-methyl-2H-tetrazol-5-YL)-phenol
5-(3,5-dimethyl-4-(3-(3-methyl-1,2-oxazol-5-yl)propoxy)phenyl)-2-methyl-2H-1,2,3,4-tetrazole
5-{3,5-dimethyl-4-[3-(3-methyl-1,2-oxazol-5-yl)propoxy]phenyl}-2-methyl-2h-1,2,3,4-tetrazole
WIN61209
CHEMBL82304
SCHEMBL9089893
WIN 61209
DB08713
5-[3-[2,6-dimethyl-4-(2-methyltetrazol-5-yl)phenoxy]propyl]-3-methyl-1,2-oxazole
Isoxazole, 5-[3-[2,6-dimethyl-4-(2-methyl-2H-tetrazol-5-yl)phenoxy]propyl]-3-methyl-
PD004188
W01
NS00069132
Q27097899
5-[3-[2,6-dimethyl-4-(2-methyltetrazol-5-yl)phenoxy]propyl]-3-methyl-isoxazole
5-{3,5-dimethyl-4-[3-(3-methylisoxazol-5-yl)propoxy]phenyl}-2-methyl-2H-tetrazole