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NADP+

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Identification
Molecular formula
C21H29N7O17P3
CAS number
53-59-8
IUPAC name
[[5-(3-carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] [3-hydroxy-5-(6-oxo-3H-purin-9-yl)-4-phosphonooxy-tetrahydrofuran-2-yl]methyl hydrogen phosphate
State
State

At room temperature, NADP+ is typically found as a solid powder. It is stable and commonly used in biochemical studies and applications.

Melting point (Celsius)
140.00
Melting point (Kelvin)
413.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
745.42g/mol
Molar mass
745.4210g/mol
Density
2.4700g/cm3
Appearence

NADP+ appears as a white to off-white powder or crystalline solid when purified. Due to its biological source and method of preparation, it may appear slightly differently in laboratory preparations.

Comment on solubility

Solubility of [5-(3-carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] [3-hydroxy-5-(6-oxo-3H-purin-9-yl)-4-phosphonooxy-tetrahydrofuran-2-yl]methyl hydrogen phosphate

The compound with the chemical formula C21H29N7O17P3 exhibits interesting solubility properties that are characteristic of its intricate structure. Understanding its solubility is crucial for various applications, especially in pharmacology and biochemistry.

Solubility Insights

  • Aqueous Solubility: Due to the presence of multiple functional groups such as hydroxyl (-OH) and phosphate (PO4), this compound is likely to have considerable solubility in water. These polar groups facilitate hydrogen bonding with water molecules.
  • Solubility in Organic Solvents: Its complex structure may also allow solubility in organic solvents, albeit to a lesser extent, depending on the specific hydrophobic regions present.
  • pH Dependence: The solubility of such compounds can be significantly influenced by the pH of the surrounding medium. For instance, at lower pH levels (acidic conditions), certain groups may become protonated, enhancing solubility, while at higher pH (alkaline conditions), deprotonation may also occur, affecting its solubility profile.
  • Thermodynamics: The solubility can also be associated with the thermodynamic properties of the compound, where enthalpic and entropic factors play key roles. Enhanced solubility often correlates with favorable solvation enthalpies.

In conclusion, the solubility of this compound can be described as multifaceted and context-dependent, influenced by its structural characteristics and the surrounding chemical environment. Further studies are needed to explore its solubility dynamics in various solvents and conditions.

Interesting facts

Interesting Facts about [5-(3-carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] [3-hydroxy-5-(6-oxo-3H-purin-9-yl)-4-phosphonooxy-tetrahydrofuran-2-yl]methyl hydrogen phosphate

This complex compound represents a fascinating intersection of organic chemistry, biochemistry, and pharmacology. Its structure suggests a multifunctional role within biological systems, particularly as possible intermediates or active components in medicinal chemistry.

Key Highlights:

  • Molecular Diversity: The presence of multiple functional groups, including phosphoryl and carbamoylpyridin-1-ium, indicates its potential reactivity and versatility in various organic reactions.
  • Phosphoryl Group Impact: Phosphorylation plays a crucial role in biological processes such as energy transfer and signaling. This compound could be integral in these pathways.
  • Potential Medicinal Applications: The purinyl component may suggest a role in nucleic acid chemistry, making this compound of interest for drug design targeting nucleic acid interactions.
  • Synthetic Challenge: The synthesis of such complex molecules often requires sophisticated techniques, showcasing the incredible skill and ingenuity of chemists in navigating multistep synthesis strategies.

As noted by famous chemist Linus Pauling, “The best way to have a good idea is to have lots of ideas.” This compound exemplifies that notion, as its intricate design reflects extensive chemical knowledge and creativity, paving the way for innovative research in the realms of pharmaceuticals and biotechnology.

Continuing to explore compounds like this opens up new avenues for scientific understanding and the development of novel therapeutic agents, making it an exciting area for ongoing study in chemistry.