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5-[(3-chlorophenyl)sulfanyl-methyl]-2H-tetrazole

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Identification
Molecular formula
C8H6ClN4S
CAS number
34233-71-5
IUPAC name
5-[(3-chlorophenyl)sulfanylmethyl]-2H-tetrazole
State
State

At room temperature, 5-[(3-chlorophenyl)sulfanylmethyl]-2H-tetrazole is typically a solid.

Melting point (Celsius)
143.00
Melting point (Kelvin)
416.00
Boiling point (Celsius)
290.00
Boiling point (Kelvin)
563.00
General information
Molecular weight
214.67g/mol
Molar mass
214.6700g/mol
Density
1.4500g/cm3
Appearence

The compound typically appears as a crystalline solid. Its color can range from white to off-white or slightly yellow, depending on purity and the presence of any impurities or degradation products.

Comment on solubility

Solubility of 5-[(3-chlorophenyl)sulfanylmethyl]-2H-tetrazole

The solubility of 5-[(3-chlorophenyl)sulfanylmethyl]-2H-tetrazole is an intriguing aspect worth exploring. This compound, due to its unique structural features, exhibits a moderate degree of solubility in various solvents.

Key points regarding its solubility include:

  • Polar Solvents: The presence of polar functional groups typically enhances solubility in polar solvents such as water and methanol.
  • Organic Solvents: It is also soluble in many organic solvents, including dimethyl sulfoxide (DMSO) and acetone, which can facilitate its application in organic synthesis.
  • Temperature Effects: Generally, the solubility of organic compounds can increase with temperature, making it important to consider the conditions under which the solubility is measured.

In summary, the solubility behavior of 5-[(3-chlorophenyl)sulfanylmethyl]-2H-tetrazole highlights the importance of both the solvent characteristics and the structural attributes of the compound itself. As such, the phrase "like dissolves like" is especially pertinent, illustrating that the solubility interactions are critical in determining the compound's utility in both research and practical applications.

Interesting facts

Interesting Facts about 5-[(3-Chlorophenyl)sulfanylmethyl]-2H-tetrazole

The compound 5-[(3-chlorophenyl)sulfanylmethyl]-2H-tetrazole is notable for several reasons, particularly in the fields of medicinal chemistry and material science. Here are some fascinating insights:

  • Diverse Applications: This compound belongs to the class of tetrazoles, which have shown significant potential in pharmaceutical applications. Tetrazoles are known for their role as bioisosteres of carboxylic acids and have been explored as anti-inflammatory, analgesic, and antimicrobial agents.
  • Structural Versatility: The presence of the sulfoxide functional group and the chlorophenyl moiety in its structure introduces unique properties. These substitutions can enhance the compound's reactivity and solubility, making it versatile for various chemical reactions.
  • Mechanisms of Action: Compounds like 5-[(3-chlorophenyl)sulfanylmethyl]-2H-tetrazole can interact with biological targets, influencing enzyme activities or receptor interactions. This interference can lead to therapeutic effects, showcasing the significance of detailed mechanistic studies.
  • Research Interest: Ongoing research is focused on understanding the pharmacodynamics and pharmacokinetics of tetrazole derivatives. Scientists are optimistic about discovering more applications in drug design and development.
  • Safety and Toxicology: Like many chemical compounds, rigorous evaluations are necessary to determine the safety profile of 5-[(3-chlorophenyl)sulfanylmethyl]-2H-tetrazole. Research typically investigates toxicity, bioavailability, and metabolic pathways to ensure safe usage in potential therapeutic applications.

The study of compounds such as 5-[(3-chlorophenyl)sulfanylmethyl]-2H-tetrazole reinforces the importance of interdisciplinary approaches in modern chemistry. Understanding their potential impacts on health and industry requires collaboration between chemists, biologists, and medical professionals.

As Albert Einstein once said, “Scientists investigate that which already is; engineers create that which has never been.” The exploration of complex compounds continues to bridge the gap between existing knowledge and innovative solutions in science.

Synonyms
1H-Tetrazole, 5-(((m-chlorophenyl)thio)methyl)-
18527-35-0
BL-J 433
BRN 1119365
5-(3-Chlorophenylthiomethyl)tetrazole
HK774HL6E5
DTXSID40171763
5-(M-CHLOROPHENYLTHIOMETHYL) TETRAZOLE
5-(((3-CHLOROPHENYL)THIO)METHYL)-2H-TETRAZOLE
1H-TETRAZOLE, 5-(((3-CHLOROPHENYL)THIO)METHYL)-
2H-TETRAZOLE, 5-(((3-CHLOROPHENYL)THIO)METHYL)-
DTXCID3094254
5-[(3-chlorophenyl)sulfanylmethyl]-2H-tetrazole
UNII-HK774HL6E5
AKOS015490419