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5-(3-Fluorophenyl)-2,4-dimethyl-1,2,4-triazole-3-thione

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Identification
Molecular formula
C10H9FN3S
CAS number
3142-87-4
IUPAC name
5-(3-fluorophenyl)-2,4-dimethyl-1,2,4-triazole-3-thione
State
State

At room temperature, 5-(3-fluorophenyl)-2,4-dimethyl-1,2,4-triazole-3-thione is in a solid state. It is typically stored in powdered form.

Melting point (Celsius)
174.00
Melting point (Kelvin)
447.15
Boiling point (Celsius)
262.00
Boiling point (Kelvin)
535.15
General information
Molecular weight
209.27g/mol
Molar mass
209.2270g/mol
Density
1.3400g/cm3
Appearence

5-(3-Fluorophenyl)-2,4-dimethyl-1,2,4-triazole-3-thione typically appears as a crystalline solid. The color is often white or off-white, depending on the purity and specific formulation of the sample.

Comment on solubility

Solubility of 5-(3-fluorophenyl)-2,4-dimethyl-1,2,4-triazole-3-thione

The solubility of 5-(3-fluorophenyl)-2,4-dimethyl-1,2,4-triazole-3-thione can be influenced by several factors. Below are some key considerations regarding its solubility:

  • Solvent Type: This compound is typically more soluble in organic solvents such as ethanol and methanol compared to water. Its hydrophobic nature due to the aromatic fluorophenyl ring affects its interaction with polar solvents.
  • Temperature: As with many organic compounds, increasing the temperature generally enhances solubility. Therefore, warming a solution may lead to better dissolution.
  • Concentration: The solubility limit can vary with concentration, and saturation may occur, leading to undissolved residues if the concentration exceeds the solubility threshold.

In practical applications, it is essential to determine the solubility of this compound in the specific solvent system intended for use. One might say that "the right solvent can unlock a compound's potential," emphasizing the need to choose solvents carefully for optimal solubility and reactivity.

Overall, while exact solubility data may vary, understanding the factors that influence the solubility of 5-(3-fluorophenyl)-2,4-dimethyl-1,2,4-triazole-3-thione is critical for effective use in chemical and pharmaceutical processes.

Interesting facts

Interesting Facts About 5-(3-Fluorophenyl)-2,4-dimethyl-1,2,4-triazole-3-thione

The compound 5-(3-fluorophenyl)-2,4-dimethyl-1,2,4-triazole-3-thione belongs to a class of organic compounds known as triazoles. These compounds are notable for their unique 5-membered ring structure that contains three nitrogen atoms.

Key Points of Interest

  • Biological Activity: Triazole derivatives, including this compound, are frequently investigated for their potential as fungicides and pharmaceuticals. Their ability to inhibit fungal cytochrome P450 enzymes makes them crucial in agricultural and medicinal chemistry.
  • Fluoro-substitution Effects: The presence of a fluorine atom in the phenyl ring can lead to enhanced biological activity and stability. This makes the compound of particular interest in drug design due to the fluorine's electronegative nature, influencing the overall reactivity of the triazole ring.
  • Applications: This compound could be explored for its therapeutic applications, particularly in treating infections caused by fungi or as a lead compound for developing new antifungal agents.

As researchers continue to explore the properties and applications of triazole compounds, 5-(3-fluorophenyl)-2,4-dimethyl-1,2,4-triazole-3-thione stands out as a promising candidate in the quest for effective new medications. Understanding the intricacies of its structure and reactivity can pave the way for innovative applications in medicinal chemistry.

Overall, the study of triazoles highlights the beauty and complexity of organic chemistry and exemplifies how slight modifications at the molecular level can lead to significant changes in behavior and utility.

Synonyms
Suritozole
110623-33-1
MDL-26479
MDL 26,479
2,4-Dihydro-2,4-dimethyl-5-(3-fluorophenyl)-3H-1,2,4-triazole-3-thione
5-(3-fluorophenyl)-2,4-dimethyl-1,2,4-triazole-3-thione
3H-1,2,4-Triazole-3-thione, 5-(3-fluorophenyl)-2,4-dihydro-2,4-dimethyl-
3-(3-fluorophenyl)-1,4-dimethyl-4,5-dihydro-1H-1,2,4-triazole-5-thione
3H7H68317X
Suritozole [USAN:INN]
BRN 6725971
Suritozol
UNII-3H7H68317X
SURITOZOLE [INN]
Suritozole (USAN/INN)
SURITOZOLE [USAN]
3-(m-Fluorophenyl)-1,4-dimethyl-delta(sup 2)-1,2,4-triazoline-5-thione
SURITOZOLE [WHO-DD]
SCHEMBL121081
CHEMBL278764
DTXSID10149333
CHEBI:177573
IWDUZEHNLHFBRZ-UHFFFAOYSA-N
3-(m-Fluorophenyl-1,4-dimethyl-delta(sup 2)-1,2,4-triazoline-5-thione
3H-1,2,4-Triazole-3-thione, 2,4-dihydro-2,4-dimethyl-5-(3-fluorophenyl)-
AKOS027201111
TS-09827
HY-114706
CS-0064137
NS00122394
D05980
EN300-253548
Q7646369
BRD-K98557884-001-01-6
Z1509672221
5-(3-luorophenyl)-2,4-dimethyl-1,2,4-triazole-3-thione
5-(3-FLUOROPHENYL)-2,4-DIHYDRO-2,4-DIMETHYL-3H-1,2,4-TRIAZOLE-3-THIONE