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Identification
Molecular formula
C10H11N3O2
CAS number
141532-71-2
IUPAC name
5-[(3-methylphenoxy)methyl]-1,3,4-oxadiazol-2-amine
State
State

At room temperature, the compound is in a solid state.

Melting point (Celsius)
182.30
Melting point (Kelvin)
455.45
Boiling point (Celsius)
401.50
Boiling point (Kelvin)
674.65
General information
Molecular weight
191.21g/mol
Molar mass
191.2070g/mol
Density
1.2400g/cm3
Appearence

The compound is typically a white to off-white solid. In its pure form, it may appear as crystalline powder.

Comment on solubility

Solubility of 5-[(3-methylphenoxy)methyl]-1,3,4-oxadiazol-2-amine

The solubility of 5-[(3-methylphenoxy)methyl]-1,3,4-oxadiazol-2-amine is influenced by several factors, given its complex structure. Understanding its solubility profile is essential for applications in pharmaceuticals, agrochemicals, and materials science. Below are key points detailing its solubility characteristics:

  • Solvent Dependence: The solubility of this compound is expected to vary significantly between polar and non-polar solvents. Typically, oxadiazoles exhibit better solubility in polar organic solvents.
  • Hydrophobic Interactions: The presence of the 3-methylphenoxy group contributes to hydrophobic interactions, which may limit solubility in water.
  • Temperature Effects: Like many organic compounds, solubility may increase with temperature. Conducting solubility tests at different temperatures can provide insight into its behavior in various environments.
  • pH Influence: The amine functional group may undergo protonation depending on the pH of the solution, which could enhance solubility under acidic conditions.
  • Potential Applications: Understanding the solubility is crucial as it directly impacts the bioavailability of the compound in drug development, where high solubility often correlates with better absorption.

In conclusion, the solubility of 5-[(3-methylphenoxy)methyl]-1,3,4-oxadiazol-2-amine is multifaceted, dictated by interactions with solvents, temperature, and pH. Conducting detailed experimental evaluations will provide a comprehensive solubility profile, which is vital for its practical applications.

Interesting facts

Interesting Facts about 5-[(3-methylphenoxy)methyl]-1,3,4-oxadiazol-2-amine

This intriguing compound, 5-[(3-methylphenoxy)methyl]-1,3,4-oxadiazol-2-amine, is a member of the oxadiazole family, a class of compounds known for their diverse biological activity. Here are some noteworthy points about this remarkable molecule:

  • Structure and Functionality: The presence of the oxadiazole ring in its structure gives the compound unique properties that can influence its chemical reactivity and interaction with biological targets.
  • Biological Significance: Compounds like this one have potential applications in pharmacology, particularly as antimicrobial or antitumor agents. This is largely due to their ability to disrupt cellular processes.
  • Versatile Synthesis: The synthesis of 5-[(3-methylphenoxy)methyl]-1,3,4-oxadiazol-2-amine can be achieved through various methods, demonstrating the versatility and adaptability researchers have in designing compounds in this class.
  • Research Interest: Ongoing investigations into the properties of oxadiazoles have garnered significant interest in medicinal chemistry, encouraging the development of new derivatives with enhanced efficacy and reduced toxicity.

As a compound that bridges organic chemistry and pharmacology, 5-[(3-methylphenoxy)methyl]-1,3,4-oxadiazol-2-amine illustrates the power of molecular design in creating substances that could potentially lead to groundbreaking therapeutic advancements. As stated by many chemists, "The future of medicine lies in the intricacies of molecular structures and their biological implications."

Synonyms
21520-92-3
1,3,4-OXADIAZOLE, 2-AMINO-5-(m-TOLYLOXYMETHYL)-
DTXSID90175857
2-Amino-5-(m-tolyloxymethyl)-1,3,4-oxadiazole
RefChem:1052508
DTXCID0098348
NIOSH/RO0548500
AKOS022212545
RO05485000
5-((3-Methylphenoxy)methyl)-1,3,4-oxadiazol-2-amine
1,3,4-Oxadiazol-2-amine, 5-((3-methylphenoxy)methyl)-