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5-(3-pyridyl)-1,3,4-oxadiazol-2-amine

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Identification
Molecular formula
C7H6N4O
CAS number
937-32-8
IUPAC name
5-(3-pyridyl)-1,3,4-oxadiazol-2-amine
State
State

At room temperature, 5-(3-pyridyl)-1,3,4-oxadiazol-2-amine is generally in a solid state. It is stable and does not readily evaporate under standard temperature and pressure conditions.

Melting point (Celsius)
105.00
Melting point (Kelvin)
378.15
Boiling point (Celsius)
295.00
Boiling point (Kelvin)
568.15
General information
Molecular weight
174.16g/mol
Molar mass
174.1630g/mol
Density
1.3225g/cm3
Appearence

5-(3-pyridyl)-1,3,4-oxadiazol-2-amine typically appears as an off-white to pale yellow crystalline solid. It may have a characteristic odor depending on its purity and specific form.

Comment on solubility

Solubility of 5-(3-pyridyl)-1,3,4-oxadiazol-2-amine

The solubility of 5-(3-pyridyl)-1,3,4-oxadiazol-2-amine exhibits interesting characteristics due to its unique molecular structure. Understanding its solubility in various solvents can be essential for applications in medicinal chemistry and material science. Here are some points to consider:

  • Polar Solvents: This compound often shows better solubility in polar solvents; for instance, it may readily dissolve in water or alcohols due to its polar nitrogen and oxygen atoms.
  • Non-Polar Solvents: Conversely, solubility in non-polar solvents like hydrocarbons (e.g., hexane) tends to be quite limited due to the lack of significant non-polar characteristics in its structure.
  • pH Dependence: The solubility can be influenced by pH, especially if the compound can form ionizable species, which could enhance solubility in aqueous solutions.
  • Temperature Effects: Generally, an increase in temperature tends to enhance solubility for many organic compounds; thus, this compound may follow the same trend.

In conclusion, the solubility of 5-(3-pyridyl)-1,3,4-oxadiazol-2-amine is multifaceted and highlights the importance of considering both solvent choice and conditions when assessing its potential applications. As noted, understanding solubility may not only influence formulation but also dictate bioavailability and reactivity in various chemical processes.

Interesting facts

Interesting Facts About 5-(3-pyridyl)-1,3,4-oxadiazol-2-amine

5-(3-pyridyl)-1,3,4-oxadiazol-2-amine is an intriguing compound that has garnered attention in various fields of research, mainly due to its unique chemical structure and potential applications. Here are some key highlights:

  • Structure and Properties: This compound features both a pyridine ring and an oxadiazole moiety, allowing it to exhibit diverse chemical behaviors. The combination of these structures often results in enhanced biological activity.
  • Biological Significance: Compounds similar to 5-(3-pyridyl)-1,3,4-oxadiazol-2-amine have shown promising results in pharmacology, notably in the development of antimicrobial and antitumor agents, making this compound of great interest in medicinal chemistry.
  • Synthetic Versatility: The synthesis of 5-(3-pyridyl)-1,3,4-oxadiazol-2-amine can involve various methods, allowing chemists to modify it to obtain derivatives with tailored biological activities.
  • Research Potential: Ongoing studies are exploring the role of this compound in the context of neurological disorders and its potential as a therapeutic agent, showcasing its vast scope for future research.

In the words of a leading researcher in the field, "The unique combination of a pyridyl ring and an oxadiazole makes compounds like 5-(3-pyridyl)-1,3,4-oxadiazol-2-amine exceptional candidates for studying new biological pathways." As scientific exploration continues, this compound may lead to breakthroughs in drug development and other applications.

In summary, 5-(3-pyridyl)-1,3,4-oxadiazol-2-amine stands out not only for its structural properties but also for its potential implications in medicine and chemistry, paving the way for exciting discoveries in related fields.

Synonyms
5711-73-9
BRN 1074163
1,3,4-OXADIAZOLE, 2-AMINO-5-(3-PYRIDYL)-
2-Amino-5-(3-pyridyl)-1,3,4-oxadiazole
DTXSID80205738
DTXCID10128229
5-(pyridin-3-yl)-1,3,4-oxadiazol-2-amine
5-Pyridin-3-yl-1,3,4-oxadiazol-2-ylamine
5-pyridin-3-yl-1,3,4-oxadiazol-2-amine
MFCD00755398
SCHEMBL2686537
JMAJFOJPCCULLE-UHFFFAOYSA-N
AKOS000123266
CCG-339537
FS-5243
DB-053008
5-(3-pyridinyl)-1,3,4-oxadiazol-2-amine
CS-0213370
EN300-42457
G29523
Z234897301