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Carteolol

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Identification
Molecular formula
C16H24N2O3
CAS number
51781-21-6
IUPAC name
5-[3-(tert-butylamino)-2-hydroxy-propoxy]tetralin-1-one
State
State

Cateolol is typically found in a solid state at room temperature.

Melting point (Celsius)
99.00
Melting point (Kelvin)
372.15
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.15
General information
Molecular weight
292.38g/mol
Molar mass
292.3820g/mol
Density
1.1000g/cm3
Appearence

Cateolol appears as a white to off-white crystalline powder. It is odorless or may have a very slight odor. The compound is generally provided in its hydrochloride form for pharmaceutical uses.

Comment on solubility

Solubility of 5-[3-(tert-butylamino)-2-hydroxy-propoxy]tetralin-1-one (C16H24N2O3)

The solubility of 5-[3-(tert-butylamino)-2-hydroxy-propoxy]tetralin-1-one is of particular interest due to its unique structure and functional groups. Understanding its solubility can provide insights into its behavior in different environments and applications. Here are some key points to consider:

  • Apolar Character: The presence of the tert-butyl group adds significant hydrophobic character, potentially limiting solubility in polar solvents like water.
  • Functional Groups: The amino and hydroxy groups can enhance solubility in polar solvents due to their ability to form hydrogen bonds, meaning the compound may show better solubility in alcohols or other organic solvents with hydrogen bond-donating capabilities.
  • Temperature Dependency: Solubility can vary with temperature, and elevated temperatures may increase the solubility of the compound in suitable solvents by overcoming intermolecular interactions.

In summary, while the overall solubility of 5-[3-(tert-butylamino)-2-hydroxy-propoxy]tetralin-1-one in water is likely to be limited due to its hydrophobic character, the positive effects of its functional groups on solubility in organic solvents cannot be disregarded. This dual nature of solubility emphasizes the importance of testing under specific conditions to accurately characterize its behavior.

Interesting facts

Interesting Facts about 5-[3-(tert-butylamino)-2-hydroxy-propoxy]tetralin-1-one

This intriguing compound is primarily known for its diverse applications in medicinal chemistry. The structural features of 5-[3-(tert-butylamino)-2-hydroxy-propoxy]tetralin-1-one contribute to its potential as a therapeutic agent, particularly in the modulation of neurological pathways. Here are some engaging highlights about this compound:

  • Complex Structure: The presence of a tetralin ring system signifies a unique three-dimensional arrangement that may influence its interaction with biological targets.
  • Hydroxyl Group: The 2-hydroxy group attached to the propane chain enhances the compound's reactivity and solubility, which is critical for its biological activity.
  • Stability and Activity: The tert-butylamino moiety is known for providing steric hindrance, potentially stabilizing the compound during reactions and offering enhanced affinity towards specific receptors.
  • Research Interest: Ongoing studies are focused on understanding how this compound may play a role in treating conditions related to the central nervous system, showcasing its importance in neurological research.
  • Multifunctionality: The potential to modify the side chains of this compound offers a pathway to develop a variety of derivatives, each with unique properties and activities.

In essence, 5-[3-(tert-butylamino)-2-hydroxy-propoxy]tetralin-1-one serves as a fascinating example of how organic chemistry is intricately linked to pharmacology and therapeutic development. As stated by many researchers, "Understanding the nuances of synthetic compounds can lead to groundbreaking innovations in medicine."

Synonyms
Bunolol
27591-01-1
Bunolol [INN]
(+/-)-Bunolol
BRN 1887243
Racemic bunolol;dl-Bunolol
71QSY2UT3G
5-[3-(tert-butylamino)-2-hydroxypropoxy]-3,4-dihydro-2H-naphthalen-1-one
CHEBI:29110
5-[3-(tert-butylamino)-2-hydroxypropoxy]-3,4-dihydronaphthalen-1(2H)-one
1(2H)-NAPHTHALENONE, 3,4-DIHYDRO-5-(3-(tert-BUTYLAMINO)-2-HYDROXYPROPOXY)-
1(2H)-Naphthalenone, 5-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]-3,4-dihydro-
W-6421A
Bunololo [DCIT]
l-Bunolol
Bunololo
Bunololum
Bunololum [INN-Latin]
(+/-)-5-[(tert-Butylamino)-2'-hydroxypropoxy]-3,4-dihydro-1(2H)-naphthalenone
UNII-71QSY2UT3G
racemic bunolol
1(2H)-Naphthalenone, 5-(3-((1,1-dimethylethyl)amino)-2-hydroxypropoxy)-3,4-dihydro-
BUNOLOL [MART.]
3,4-Dihydro-5-(3-(tert-butylamino)-2-hydroxy)propoxy-1(2H)-naphthalenone
GTPL570
SCHEMBL828612
CHEMBL293030
DTXSID7022702
NCGC00263903-02
SBI-0206800.P001
DB-051429
NS00093645
C04883
AB01563321_01
L000824
BRD-A46876182-003-01-0
BRD-A46876182-003-02-8
Q27104064
(+-)-5-[3-(tert-butylamino)-2-hydroxypropoxy]-3,4-dihydronaphthalen-1(2H)-one
(+/-)-5-(3-(TERT-BUTYLAMINO)-2-HYDROXYPROPOXY)-3,4-DIHYDRO-1(2H)-NAPHTHALENONE
(+/-)-5-[(tert-butylaminol)-2'-hydroxypropoxy]-3,4-dihydro-1(2H)-naphthalenone
(-)-5-[3-(tert-Butylamino)-2-hydroxypropoxy]-3,4-dihydro-1(2H)- naphthalenone
1(2H)-Naphthalenone, 5-3-(1,1-dimethylethyl)amino-2-hydroxypropoxy-3,4-dihydro-
5-[3-(tert-Butylamino)-2-hydroxypropoxy]-3,4-dihydro-1(2H)-naphthalenone #
(?)-5-[3-(tert-Butylamino)-2-hydroxypropoxy]-3,4-dihydronaphthalene-1(2H)-one hydrochloride,(?)-Bunolol hydrochloride
1(2H)-NAPHTHALENONE, 5-(3-(1,1-DIMETHYLETHYL)AMINO)-2-HYDROXYPROPOXY)-3,4-DIHYDRO-, (+/-)-