Skip to main content

Dichloralphenazone

ADVERTISEMENT
Identification
Molecular formula
C12H12Cl2N2O3
CAS number
480-30-8
IUPAC name
5-(3,4-dichlorophenyl)-5-ethyl-hexahydropyrimidine-2,4,6-trione
State
State
Dichloralphenazone is a solid at room temperature.
Melting point (Celsius)
178.00
Melting point (Kelvin)
451.15
Boiling point (Celsius)
314.00
Boiling point (Kelvin)
587.15
General information
Molecular weight
368.17g/mol
Molar mass
368.1650g/mol
Density
1.5400g/cm3
Appearence

Dichloralphenazone appears as a white or off-white crystalline powder. It is typically odorless and slightly soluble in water, more so in alcohol and chloroform.

Comment on solubility

Solubility of 5-(3,4-Dichlorophenyl)-5-ethyl-hexahydropyrimidine-2,4,6-trione

The solubility characteristics of 5-(3,4-dichlorophenyl)-5-ethyl-hexahydropyrimidine-2,4,6-trione are fascinating and reveal much about its chemical nature. This compound displays varying solubility depending on the solvent used, which is critical for its applications in various fields.

Key Points on Solubility:

  • Polar Solvents: This compound is expected to have low solubility in polar solvents such as water due to its relatively large and hydrophobic structure.
  • Non-Polar Solvents: It is likely to exhibit higher solubility in non-polar organic solvents like chloroform or hexane, reflecting the hydrophobic interactions of its aromatic and aliphatic groups.
  • Effect of Temperature: Solubility may increase with temperature, a common behavior for solid compounds, thus enhancing its dissolution in organic solvents at elevated temperatures.

As a general observation, the cyclic structure and the presence of electron-withdrawing groups like the dichlorophenyl moiety can significantly impact the solubility profile. Understanding these solubility dynamics is essential for optimizing the use of this compound in synthesis and formulation processes.

In conclusion, recognizing the solubility behavior in various solvents can lead to better applications and more efficient usage in chemical reactions.

Interesting facts

Interesting Facts about 5-(3,4-dichlorophenyl)-5-ethyl-hexahydropyrimidine-2,4,6-trione

This intriguing compound is part of the pyrimidine family, a structural class that is prevalent in various biological systems. Pyrimidines are key components of nucleic acids, such as DNA and RNA, which are essential for life as they hold the genetic blueprint in organisms. Here are some fascinating aspects of this compound:

  • Dichlorophenyl Influence: The presence of a 3,4-dichlorophenyl group can significantly alter the compound's reactivity and biological activity. Chlorine substituents are known for their electron-withdrawing properties, thereby affecting the compound's chemical behavior.
  • Biological Significance: Compounds like this one may exhibit pharmaceutical properties, making them important in medicinal chemistry. Research into their efficacy can lead to the development of new drugs.
  • Structural Complexity: The hexahydropyrimidine structure offers a unique framework, allowing for potential pharmacophoric interactions, which are crucial for binding to biological targets.
  • Synthetic Routes: The synthesis of such compounds often involves multi-step processes, showcasing the creativity and skill required in organic chemistry to manipulate molecular structures.

As with many organic compounds, the study of 5-(3,4-dichlorophenyl)-5-ethyl-hexahydropyrimidine-2,4,6-trione can potentially lead to breakthroughs in various fields, including drug discovery and materials science. The interplay of its unique structural features opens imaginative avenues for scientific exploration.

Synonyms
Dichlorophenobarbital
5-(3,4-Dichlorophenyl)-5-ethylbarbituric acid
23256-01-1
2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-(3,4-dichlorophenyl)-5-ethyl-
YSS6L99D7B
DTXSID00177827
RefChem:133087
DTXCID60100318
5-(3,4-dichlorophenyl)-5-ethyl-1,3-diazinane-2,4,6-trione
BRN 0689106
BARBITURIC ACID, 5-(3,4-DICHLOROPHENYL)-5-ETHYL-
5-(3,4-Dichlorophenyl)-5-ethyl barbituric acid
5-(3,4-Dichlorophenyl)-5-ethyl-2,4,6(1H,3H,5H)-pyrimidinetrione