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Pyrimethanil

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Identification
Molecular formula
C12H13N3O2
CAS number
53112-28-0
IUPAC name
5-[(3,4-dimethoxyphenyl)methyl]pyrimidine-2,4-diamine
State
State

Pyrimethanil is a solid at room temperature. It is typically processed in particulate or powder form for agricultural and chemical applications.

Melting point (Celsius)
96.00
Melting point (Kelvin)
369.00
Boiling point (Celsius)
366.00
Boiling point (Kelvin)
639.00
General information
Molecular weight
199.24g/mol
Molar mass
199.2390g/mol
Density
1.1870g/cm3
Appearence

Pyrimethanil appears as a white to off-white powder. It is commonly provided in a crystalline form and is known for its relatively stable appearance, without pronounced odors. The substance is not hygroscopic and remains stable under normal conditions, though it should be handled with care to prevent dispersion into the environment.

Comment on solubility

Solubility of 5-[(3,4-dimethoxyphenyl)methyl]pyrimidine-2,4-diamine

The solubility of 5-[(3,4-dimethoxyphenyl)methyl]pyrimidine-2,4-diamine can be influenced by several factors that are important to consider:

  • Polarity: The presence of methoxy groups in the structure tends to increase the polarity of the compound, which may enhance its solubility in polar solvents such as water and alcohols.
  • Solvent Interactions: Solubility is often best in solvents that can form hydrogen bonds with the solute. Therefore, 5-[(3,4-dimethoxyphenyl)methyl]pyrimidine-2,4-diamine might show good solubility in organic solvents, particularly those with similar functional groups.
  • pH Dependence: The solubility can also be pH-dependent due to the presence of amino groups which can be protonated, thereby potentially increasing solubility in acidic conditions.

In general, it is essential to explore the following when discussing the solubility of this compound:

  1. Concentration of solute and solvent.
  2. Temperature, as increasing it typically enhances solubility.
  3. Specific interactions with the solvent molecules that can lead to dissolution.

Ultimately, while solubility may vary depending on environmental conditions, understanding these factors can help in predicting how 5-[(3,4-dimethoxyphenyl)methyl]pyrimidine-2,4-diamine will behave in different solvent systems. As a general rule, **"like dissolves like"**, so consider solvents with similar polarities for optimal solubility.

Interesting facts

Interesting Facts about 5-[(3,4-Dimethoxyphenyl)methyl]pyrimidine-2,4-diamine

This compound, known as 5-[(3,4-dimethoxyphenyl)methyl]pyrimidine-2,4-diamine, belongs to a fascinating class of organic molecules that exhibit a variety of biological activities. Here are some intriguing aspects to explore:

  • Biological Significance: Compounds like this one are often studied for their potential therapeutic effects. They may act as inhibitors or modulators in biochemical pathways, which makes them valuable in the field of medicinal chemistry.
  • Structural Features: The presence of a pyrimidine ring, a common motif in pharmaceuticals, contributes to the compound's reactivity and interaction with biological targets.
  • Molecular Diversity: The incorporation of the 3,4-dimethoxyphenyl group enhances the compound's chemical properties and influences its biological activity, showcasing the importance of structural modifications in drug design.
  • Research Applications: Researchers are continually exploring its applications in various fields, such as cancer treatment and neurobiology, emphasizing the compound's importance in ongoing scientific advancements.
  • Quote from the Literature: As one study noted, *"The modulation of pyrimidine derivatives presents promising avenues in drug discovery and development,"* highlighting the ongoing relevance of such compounds in pharmaceutical research.

Overall, 5-[(3,4-dimethoxyphenyl)methyl]pyrimidine-2,4-diamine exemplifies the intricate relationship between structure and function in chemical compounds and underscores the exciting potential of organic chemistry in developing future therapeutics.

Synonyms
DIAVERIDINE
5355-16-8
Diaveridin
Diaveridina
Diaveridinum
2,4-Diamino-5-veratrylpyrimidine
5-(3,4-dimethoxybenzyl)pyrimidine-2,4-diamine
BW 49-210
2,4-Diamino-5-(3,4-dimethoxybenzyl)pyrimidine
EGIS-5645
Diaveridinum [INN-Latin]
Diaveridina [INN-Spanish]
5-((3,4-Dimethoxyphenyl)methyl)-2,4-pyrimidinediamine
Diaveridine [USAN:INN:BAN]
CCRIS 3784
Pyrimidine, 2,4-diamino-5-veratryl-
NSC-408735
EGIS 5645
CHEBI:123115
AI3-23935
EINECS 226-333-3
2,4-Pyrimidinediamine, 5-[(3,4-dimethoxyphenyl)methyl]-
NSC 408735
BRN 0258464
7KVX81XA87
DTXSID2046200
DIAVERIDINE [MI]
DIAVERIDINE [INN]
DIAVERIDINE [USAN]
DIAVERIDINE [MART.]
BW-49210
DIAVERIDINE [USP-RS]
BW-49-210
2,4-Pyrimidinediamine, 5-((3,4-dimethoxyphenyl)methyl)-
DTXCID0026200
5-25-13-00391 (Beilstein Handbook Reference)
Diaveridinum (INN-Latin)
Diaveridina (INN-Spanish)
DIAVERIDINE (MART.)
DIAVERIDINE (USP-RS)
Pyrimidine, 2,4-diamino-5-veratryl-(8CI)
226-333-3
5-[(3,4-dimethoxyphenyl)methyl]pyrimidine-2,4-diamine
5-(3,4-Dimethoxy-benzyl)-pyrimidine-2,4-diamine
CHEMBL19633
MFCD00057349
NSC408735
NCGC00160517-01
Diaveridine 10 microg/mL in Acetonitrile
CAS-5355-16-8
UNII-7KVX81XA87
Diverdine
Diaveridine (Standard)
Diaveridine (USAN/INN)
Epitope ID:119685
5-(3,4-Dimethoxybenzyl)-2,4-pyrimidinediamine
SCHEMBL93896
2,4-Diamino-5-(3',4'-dimethoxybenzyl)pyrimidine
MLS004712092
2,4-dimethoxybenzyl)pyrimidine
HY-B1902R
Pyrimidine,4-diamino-5-veratryl-
HMS3264I16
Pharmakon1600-01502300
HY-B1902
Tox21_111866
BBL009897
BDBM50138691
NSC759634
s5200
STK711076
AKOS005530708
Tox21_111866_1
CCG-213021
FD66116
NSC-759634
2, 5-[(3,4-dimethoxyphenyl)methyl]-
NCGC00160517-02
NCGC00160517-03
AC-12110
AS-56306
BW 49210
SMR002529995
CS-0013961
NS00000684
210U49
D03771
D81857
AB01562957_01
Diaveridine, VETRANAL(TM), analytical standard
EN300-7440332
5-(3,4-Dimethoxybenzyl)-2,4-pyrimidinediamine #
A829660
SR-01000939849
2,4-diamino-5-(3',4'-dimethoxybenzyl) pyrimidine
2,4-diamino-5-(3',4'-dimethoxybenzyl)-pyrimidine
Diaveridine, analytical standard, >=99.0% (TLC)
SR-01000939849-2
BRD-K97464279-001-03-5
Q27212503
Z2681892420
Diaveridine, United States Pharmacopeia (USP) Reference Standard
KUP