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Trimethoxyamphetamine

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Identification
Molecular formula
C16H19ClNO4
CAS number
83285-64-3
IUPAC name
5-(3,4,5-trimethoxyphenyl)-7,8-dihydro-[1,3]dioxolo[4,5-g]isoquinolin-6-ium;chloride
State
State

Solid at room temperature, typically appearing as a white crystalline powder.

Melting point (Celsius)
145.00
Melting point (Kelvin)
418.15
Boiling point (Celsius)
265.40
Boiling point (Kelvin)
538.55
General information
Molecular weight
317.82g/mol
Molar mass
317.8200g/mol
Density
1.2000g/cm3
Appearence

The compound appears as a white crystalline solid.

Comment on solubility

Solubility of 5-(3,4,5-trimethoxyphenyl)-7,8-dihydro-[1,3]dioxolo[4,5-g]isoquinolin-6-ium;chloride

The solubility of the compound 5-(3,4,5-trimethoxyphenyl)-7,8-dihydro-[1,3]dioxolo[4,5-g]isoquinolin-6-ium;chloride can be intriguing due to its unique structural characteristics. Generally, the solubility of a compound in a solvent can be influenced by various factors, including:

  • Polarity: The presence of polar functional groups can increase solubility in polar solvents.
  • Interactions: Ionic compounds often exhibit good solubility in polar solvents due to ion-dipole interactions.
  • Hydrogen bonding: Compounds capable of hydrogen bonding typically show enhanced solubility in solvents able to participate in such bonding.

In the case of this compound, which contains both ionic and polar characteristics due to its quaternary ammonium structure and multiple methoxy groups, it may demonstrate:

  • Good solubility in water: The chloride ion enhances solubilization due to its ionic nature.
  • Increased solubility in organic solvents: Such as alcohols and acetone due to the methoxy groups.
  • Variable solubility in non-polar solvents: Likely lower due to the compound's polar attributes.

In conclusion, the solubility of 5-(3,4,5-trimethoxyphenyl)-7,8-dihydro-[1,3]dioxolo[4,5-g]isoquinolin-6-ium;chloride is expected to be influenced by its ionic and polar characteristics, making it more soluble in polar solvents while potentially less soluble in non-polar environments. As always, empirical testing is essential for precise solubility determination.

Interesting facts

Interesting Facts about 5-(3,4,5-trimethoxyphenyl)-7,8-dihydro-[1,3]dioxolo[4,5-g]isoquinolin-6-ium;chloride

This compound, commonly referred to as a member of the isoquinoline family, exhibits some remarkable properties that intrigue both scientists and researchers in the field of medicinal chemistry. Here are some interesting facts:

  • Pharmacological Potential: Isoquinolines, including this compound, have been investigated for their potential as therapeutic agents, particularly in the treatment of cancer and neurological disorders due to their unique chemical structure.
  • Natural Inspirations: Many compounds in the isoquinoline series are found in nature, particularly in plants, where they contribute to various biological activities. This compound's structural design is reminiscent of several natural alkaloids.
  • Multifunctionality: The presence of multiple methoxy groups in its structure suggests that this compound could engage in a variety of interactions, making it versatile for different applications in drug development.
  • Complex Structure: The incorporation of the dioxole ring into the isoquinoline backbone adds to its structural complexity, which can influence both its reactivity and interaction with biological targets.
  • Research Focus: This compound is of particular interest in ongoing research focusing on its synthesis and modification to explore its use as a lead compound in new drug development.

As noted by one of the prominent chemists in the field, "The intricate balance between structure and function in such compounds is what drives innovation in medicinal chemistry." This highlights the importance of exploring compounds like this one, which could lead to breakthroughs in treatment strategies.

The study of this chloride salt form further enhances its relevance, as salts often exhibit different solubility and stability profiles that are crucial for pharmaceutical applications.
In summary, 5-(3,4,5-trimethoxyphenyl)-7,8-dihydro-[1,3]dioxolo[4,5-g]isoquinolin-6-ium;chloride is a fascinating compound with a rich potential that invites further exploration.

Synonyms
1,3-Dioxolo(4,5-g)isoquinoline, 7,8-dihydro-5-(3,4,5-trimethoxyphenyl)-, hydrochloride
6271-07-4
NSC 36794
7,8-Dihydro-5-(3,4,5-trimethoxyphenyl)-1,3-dioxolo(g)isoquinoline hydrochloride