Skip to main content

Digitoxin

ADVERTISEMENT
Identification
Molecular formula
C41H64O13
CAS number
71-63-6
IUPAC name
5-[(3S,10R,12R,13S,14S,17R)-3-[(2S,3S,4R,5S,6S)-3,4-dihydroxy-6-(hydroxymethyl)-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-methyl-tetrahydropyran-2-yl]oxy-tetrahydropyran-2-yl]oxy-12,14-dihydroxy-10,13-dimethyl-1,2,3,6,7,8,9,11,12,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl]pyran-2-one
State
State
Digitoxin is a solid at room temperature. It is commonly used in pharmaceutical applications and must be handled with care due to its potency.
Melting point (Celsius)
255.50
Melting point (Kelvin)
528.65
Boiling point (Celsius)
797.20
Boiling point (Kelvin)
1 070.35
General information
Molecular weight
764.96g/mol
Molar mass
764.9640g/mol
Density
1.2700g/cm3
Appearence

Digitoxin typically appears as a white crystalline powder or white crystals. It is odorless and tastes bitter. The compound is quite sensitive to light and may degrade upon prolonged exposure.

Comment on solubility

Solubility of 5-[(3S,10R,12R,13S,14S,17R)-3-[(2S,3S,4R,5S,6S)-3,4-dihydroxy-6-(hydroxymethyl)-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-methyl-tetrahydropyran-2-yl]oxy-tetrahydropyran-2-yl]oxy-12,14-dihydroxy-10,13-dimethyl-1,2,3,6,7,8,9,11,12,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl]pyran-2-one

Solubility is a critical property in determining the behavior of complex organic compounds such as 5-[(3S,10R,12R,13S,14S,17R)-3-...-pyran-2-one. Here are some insights into the solubility characteristics of this compound:

  • Polar Groups: The presence of multiple hydroxyl (–OH) groups contributes to a higher affinity for polar solvents such as water. This suggests that the compound may exhibit some level of solubility in aqueous environments.

  • Hydrophobic Clusters: The intricate structure features hydrophobic regions due to the dodecahydrocyclopenta[a]phenanthren moiety, which can reduce overall solubility in polar solvents.

  • Solvent Dependence: Solubility can vary significantly depending on the solvent used. For instance, organic solvents like ethanol or methanol could potentially enhance solubility due to their ability to interact with both polar and non-polar components of the compound.

  • Temperature Influence: Increasing temperature typically improves solubility for many organic compounds, so one should consider temperature effects when assessing solubility.

  • Practical Implications: The unique solubility characteristics can affect the compound's applications in fields like pharmaceuticals, where solubility can influence bioavailability.

In conclusion, understanding the solubility dynamics of 5-[(3S,10R,12R,13S,14S,17R)-3-...-pyran-2-one is essential for its practical applications and formulations, necessitating further investigations to delineate its solubility profile under various conditions.

Interesting facts

Interesting Facts about 5-[(3S,10R,12R,13S,14S,17R)-3-[(2S,3S,4R,5S,6S)-3,4-dihydroxy-6-(hydroxymethyl)-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-methyl-tetrahydropyran-2-yl]oxy-tetrahydropyran-2-yl]oxy-12,14-dihydroxy-10,13-dimethyl-1,2,3,6,7,8,9,11,12,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl]pyran-2-one

The compound known as 5-[(3S,10R,12R,13S,14S,17R)-3-[[...]]-2-one is an intriguing example of a complex natural product that showcases the vast diversity of organic molecules found in nature. Here are some fascinating insights into this compound:

  • Structure and Chirality: This compound features multiple chiral centers, which means that it can exist in different stereochemical forms. This property is significant as each stereoisomer can exhibit distinct biological activities.
  • Natural Origins: Compounds like this are often derived from plants or fungi, and they play crucial roles in various biological processes. Their unique structures can contribute to their potential efficacy in medicinal chemistry.
  • Biological Activity: While specific studies may be limited, the complexity of this compound suggests potential interactions with biological systems. Many natural products inspire drug discovery due to their varied biochemical activities.
  • Medicinal Chemistry: The unique framework of multi-ring systems and functional groups in this compound may allow for innovative developments in pharmaceuticals, especially in targeting specific pathways within the human body.
  • Research Opportunities: Due to its complexity, this compound presents significant opportunities for research in organic synthesis and asymmetric synthesis techniques.

"The exploration of complex natural products can often reveal compounds with unique properties and profound implications for medicine and biotechnology."

Overall, 5-[(3S,10R,12R,13S,14S,17R)-3-[[...]]-2-one exemplifies the rich tapestry of organic chemistry and the potential it holds for advancements in science and health.

Synonyms
DTXSID50943812
3-{[4-O-(6-Deoxyhexopyranosyl)hexopyranosyl]oxy}-12,14-dihydroxybufa-4,20,22-trienolide